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적외선, 생물광자 및 GDV 측정의 한의학적 비교 소개
이승호 ( Seung Ho YI ),이혜정 ( Hyu Jung Lee ) 대한경락경혈학회 2010 Korean Journal of Acupuncture Vol.27 No.2
Objectives: The purpose of this study is to introduce and examine the possibilities of infrared (IR) imaging, biophoton detection and gas discharge visualization(GDV) as diagnostic tools in Korean Medicine. Methods: To review the basic mechanism and measurement methods of three modalities, concepts in physics were introduced. Physical backgrounds of IR, biophoton and GDV were briefly explained based on recent research papers. Simple electronics was employed for relevant detectors. In order to find the relation between Korean Medicine and these methods, papers on their applications were reviewed. Opinions from the experts on each modality were obtained from their papers and private communications. Results and Conclusions: IR imaging has been used as an auxiliary diagnostic tool but there are some rooms for the improvement for clinical applications. Experimental confirmation of the meridian activation by a moxa cigar is necessary for its verification. Biophoton is not correlated with human skin temperature but it has a circadian rhythm. Biophoton and GDV have a negligible relation if any. Therefore there are no correlations among three modalities in terms of basic mechanisms. But their clinical relations are yet to be scrutinized. Biophoton and GDV need more rigorous clinical tests before they can be used as diagnostic tools.
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과산화수소로 유발된 사람 신경아세포종의 아폽토시스에서 호도 약침액의 신경보호효과
김재학 ( Hak Jae Kim ),원혜진 ( Hyu Jin Won ),박해정 ( Hae Jeong Park ),라제현 ( Je Hyun Ra ),박히준 ( Hi Joon Park ),홍미숙 ( Mee Suk Hong ),임성빈 ( Sung Vin Yim ),이혜정 ( Hyu Jung Lee ),정주호 ( Joo Ho Chung ) 대한경락경혈학회 2006 Korean Journal of Acupuncture Vol.23 No.3
목적: 과산화수소는 산화적 스트레스를 통해 아폽토시스를 유도하는 것으로 알려져 있다. 본 논문에서는 과산화수소로 유발된 신경아세포종 아폽토시스 과정에서 호도약침액의 효과를 관찰하였다. 방법: 과산화수소로 인한 신경아세포종의 아폽토시스에서 호도약침액 의 효과를 알아보기 위해 배양중인 신경아세포종에 과산화수소를 처리하고, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) 분석법, 4,6-diamidino-2-phenylindole (DAPI) 염색법, reverse transcription-polymerase chain reaction (RT-PCR), western blotting의 방법으로 확인하였다. 결과: 과산화수소로 인한 신경아세포종의 아폽토시스에서 호도약침액을 처리한 결과, 약침액을 처리한 세포의 생존이 약 30% 정도 증가하고, 핵 응축과 단편화를 막아주며, CASP3와 BAX단백질의 발현이 감소되었다. 결론: 이러한 결과로 호도약침액이 과산화수소로 인한 신경아세포종의 아폽토시스과정에서 보호효과를 나타내는 것으로 사료된다.
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최소 침(Minimal Acupuncture)이 침 임상연구에서 적절한 대조군인가?
채윤병 ( Youn Byoung Chae ),김송이 ( Song Yi Kim ),이혜정 ( Hyu Jung Lee ),박히준 ( Hi Joon Park ) 대한경락경혈학회 2008 Korean Journal of Acupuncture Vol.25 No.2
Objective: Acupuncture, one of the Oriental medical treatment techniques in East Asia, is growing in popularity all over the world. Based on bibliographical and clinical data, the depth of needling, i.e. superficial or deep needling, has been considered to be a variable as potential modifiers of needling effects, such as Localization, manipulation of the needle, or elicitation of DeQi . The purpose of this review is to summarize clinical trials using minimal acupuncture and to evaluate its appropriateness as a control. Methods: A survey of computerized Literature searches for randomized controlled trials using minimal acupuncture revealed that a total of 10 studies were published until April 2008. Results: Results obtained from clinical trials showed that acupuncture were more effective than minimal acupuncture in 3 out of 10 trials, while others were no more effective than control. However, minimal acupuncture might neither be a inert placebo nor be indiscriminable. Conclusion: Minimal acupuncture as `placebo` controls seems misleading and scientifically unacceptable.
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채윤병 ( Youn Byoung Chae ),김윤주 ( Yun Ju Kim ),최일환 ( Il Hwan Choe ),임사비나 ( Sabina Lim ),이상재 ( Sang Jae Lee ),이혜정 ( Hyu Jung Lee ),박히준 ( Hi Joon Park ) 대한경락경혈학회 2006 Korean Journal of Acupuncture Vol.23 No.4
Objectives: Proper acupuncture stimulation is associated with a characteristic set of sensation usually referred to as "De-Qi". In order to develop the appropriate sham acupuncture, various sensations to each stimulation should be considered through analysis of the profiles of acupuncture sensation. It was therefore investigated to compare the acupuncture sensation scale (ASS) of two types of sham acupuncture to that of the real acupuncture. Methods: Ninety-four participants (mean age 26.4, range 22-49) were asked to complete five point-Likert scale ASS developed by Vincent et al. after real or two-kinds of sham acupuncture stimulation: blunted tip sham acupuncture (BT) and round tip sham acupuncture (RT). Needling was done at LI4 acupoint on non-dominant hand and stimulated for 30 seconds with real or two-kinds of sham needle. Finger withdrawal Latency (FWL) of each group was also measured to evaluate the pain sensitivity to noxious heat stimuli. Results: BT acupuncture significantly Less produced penetrating, numb, intense, hurting, pulling, shock, tingling, throbbing sensation than real acupuncture stimulation. RT acupuncture significantly Less produced penetrating, burning, electric, numb, intense, hurting, pulling, aching, sharp, shock, stinging, tingling, throbbing sensation than real acupuncture. Each group did not demonstrate the differences of pain sensitivity to noxious stimuli. Conclusions: These results indicated that types of tip of acupuncture produced different kinds of acupuncture sensation. Our finding provides a general information of sensations to two kinds of sham acupuncture for development of ideal placebo sham needle.
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