http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
천마 유기용매 추출물의 in vitro 항비만 및 항바이러스 활성에 관한 연구
이재우; 강병태 ; 최원경 김천대학교 2006 김천대학교 논문집 Vol.27 No.-
In order to provide the physiological activity of crude extracts of Gastrodia elata Blume, we carried out in vitro anti-obesity and anti-viral assay. Activity of anti-obesity was represent as Peroxisome proliferative activated receptory2 (PPARY2) binding capacity, which are ligand-activated transcription factors that modulate the expression of genes involved in adipocyte differentiation and lipid metabolism. Ethylacetate extract (CM/EA) and Methanol extract (CM/Me) were significantly increased the binding activity, in a dose responsive manner. against Indomethacin was utilized as PPARy agonist. We suggest that EA extract have candidate material can be used as a modulator of PPARY. Cytopathogenic effect(CPE) reduction of crude extracts were detected from porcine epidemic diarrhea virus (PEDV) -Vero cell infection system. The CM/Me showed the effect of 50% CPE reduction but CM/Me exhibited the toxic effect to Vero cell at the concentration of 100ug/ml. These results suggested that Gastrodia elata Blume may be used as functional food materials.