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- 저자 : 이유시 ( You Si Lee ) (검색결과 1 건)
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논문 : 오디추출액 급여가 일부 류머티즘 환자의 혈액성상 및 심혈관계 지표에 미친 영향
김애정 ( Ae Jung Kim ),허종일 ( Jong Il Hur ),이종국 ( Jong Kug Lee ),이유시 ( You Si Lee ),배윤정 ( Yun Jung Bae ),성미경 ( Mi Kyung Sung ),승정자 ( Chung Ja Chung ) 국제통합대체의학협회 2005 국제통합대체의학회지 Vol.1 No.1
Rheumatoid arthritis(RA) is a chronic syndrome of unknown etiology and characterizod by non-specific inflammation of the peripheral joints. Recent studies have indicated that pathogenesis of RA related tissues damages and inflammation are induced by excess production of reactive oxygen species and/or reduced ability to decrease oxidative stresses. The antocyanin pigments composed of red colored fruits such as mulberry fruits have the anti-inflammatory and anti-oxidantive effects. So this study was done to investigate the anti-inflammatory and anti-oxidantive effects of mulberry fruit extract(MFE) on the serum biochemical indices especially inflammatory indices in seven rheumatoid patients visited Health Center in Taeangun area Anthropometry measurement, serum biochemical parameters including lipid profiles, cardiovascular disease indices, inflammatory factors and serum oxidative stress makers were compared before and after administration of MFE for 2 weeks. After administration of MFE, there were no significant differences, but appeared a tendency to decrease in anthropometry measurements(BMI: body mass index, % of body fat and body fat), serum biochemical indices(serum total cholesterol, triglyceride, LDL-cholesterol, uric acid, carbon-reactive protein, rheumatoid factor, ASP: aspartate transaminase and ALT alanine transaminase) and cardiovascular disease indices(CRF: cardiac risk factor, LHR: low density lipoprotein cholesterol and Al: atherogenic index). On the other hand, there was tendency to increase in lean body mass, serum HDL-cholesterol and HTR(high density lipoprotein cholesterol and total cholesterol ratio). These results suggested careful monitoring of MFE intakes is required for these patients.
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