수부손상으로 인한 접합 환자의 외상 후 스트레스 관련 요인

이산휘,한미아,박종,류소연 대한임상건강증진학회 2016 Korean Journal of Health Promotion Vol.16 No.1

Background: The risk for a hand injury was increased according to industrial structure and lifestyle change. This study investigated the post traumatic stress (PTS) and related factors in some hand replantation patients. Methods: Total 150 hand replantation patients in one hospital were selected using convenience sampling methods. General characteristics of patients, characteristics of injured hand, self-esteem and PTS were collected using self-reported questionnaires. And clinical characteristics of injured hand were obtained from a review of medical records. Descriptive analysis, t-test, ANOVA and multiple regression analysis were performed to determine the associated factors with the score of PTS. Results: Among 150 patients, 80% were male and 94% had a job. The mean score of PTS was 22.2±16.9. In simple analysis, PTS score were associated with smoking status, injury day of the week, pain score and self-esteem. Finally, the subjects who injured in weekdays had significantly higher PTS score compared to subjects who injured in weekend (β=0.185, P=0.021) and pain score was positively associated with PTS score (β =0.181, P=0.027) in multiple regression analysis. Conclusions: Injury day of the week and pain score were associated with PTS score in some hand replantation patients. Considering these results will help to management and improve quality of life of hand replantation patients. 연구배경: 산업구조와 생활방식의 변화에 따라 수부손상의 위험요소가 다양하게 증가되었다. 이에 본 연구는 수부손상으로 수술한 환자들을 대상으로 외상 후 스트레스 및관련 요인을 파악하고자 하였다. 방법: 광주광역시 소재 일개 수부 전문병원에서 수술 후 4주 이상 지난 환자 150명을 대상으로 2014년 12월 1일부터 2015년 3월 31일까지 자료를 수집하였고 SPSS Win 18.0 을 사용하여 분석하였다. 외상 후 스트레스 관련 요인을 파악하기 위해 t 검정, 분산분석, 상관분석, 다중선형회귀분석을 실시하였다. 결과: 대상자 중 남자가 80%, 직업을 가지고 있는 경우가94%였다. 외상 후 스트레스 점수는 22.2±16.9점이었으며, 외상 후 스트레스 장애군은 34%였다. 단순분석에서 스트레스 점수는 흡연, 손상 발생 요일, 통증, 자아존중감과 관련이 있었다. 최종적으로 다중회귀분석에서 손상 발생 요일에서 주말에 손상된 경우보다 평일 손상의 경우(β=0.185, P=0.021), 통증이 증가할수록(β=0.181, P=0.027) 스트레스 점수가 유의하게 높았다. 결론: 수부접합 환자의 외상 후 스트레스는 손상 발생 요일 및 통증과 유의한 관련성이 있었다. 이러한 결과를 수부손상 환자의 치료 및 외상 후 스트레스 관리를 위한 자료로활용할 수 있을 것이다.

The Relationship of Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio with Bone Mineral Density in Korean Postmenopausal Women

이산휘,류소연,박종,신민호,한미아,최성우 전남대학교 의과학연구소 2019 전남의대학술지 Vol.55 No.3

The neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are known to be markers of the systemic inflammatory response. However, the few studies that have been done on the relationship between the NLR and PLR and osteoporosis have yielded inconsistent results. Therefore, we assessed the relationship between the NLR and PLR and bone mineral density (BMD). This study was conducted with postmenopausal patients admitted to an orthopaedic hospital. Data including BMD, NLR, PLR and covariates were obtained from the subjects’ medical records. In total, 407 postmenopausal patients were enrolled in this study. Analysis of covariance was performed to identify significant differences in BMD according to NLR and PLR. After adjusting for other covariates, a quartile of NLR was negatively associated with the mean value of lumbar BMD (p=0.040, p for trend=0.005) but not with the mean value of femur neck BMD. However, there were no significant associations among the PLR, the BMD of the lumbar and the femur neck. In conclusion, the quartile of NLR was negatively associated with the mean value of lumbar BMD in Korean postmenopausal patients.

Knowledge of HPV and Surgery among Women Who Underwent Cervical Conization: A Korean Multi-Center Study

임명철,전소연,김세익,이정윤,이산휘,송용중,천경철,김재원,박상윤 연세대학교의과대학 2016 Yonsei medical journal Vol.57 No.5

Purpose: Human papillomavirus (HPV) infection is a well-known cause of cervical cancer, which, along with its precursors, can be diagnosed and treated with cervical conization (CC). This study aimed to assess HPV- and procedure-related knowledge among women who had undergone CC. Materials and Methods: Between February and May 2014, consecutive women who had undergone CC at five different educationalhospitals were recruited. All patients had undergone a loop electrosurgical excision procedure as the method of CC. A surveywas conducted with a self-developed, 29-item questionnaire, measuring knowledge related to HPV and CC. We analyzed the responses of 160 patients who completed the questionnaire. Results: Mean total knowledge scores (±standard deviation) for HPV and CC were 5.2±3.0 of a possible 13.0 and 8.3±4.2 of a possible16.0, respectively. While 73% of the patients knew that HPV is the main cause of cervical cancer, only 44% knew that HPV is sexually transmitted. The purpose of CC was correctly identified by 71% of the patients. However, 35% failed to indicate the anatomicalarea resected at the time of CC in the schematic diagram. Women who were younger (p<0.001), had higher education level (p<0.001), and higher family income (p=0.008) had higher knowledge scores. In contrast, neither interval from CC to survey nor disease severity were associated with total knowledge score. Conclusion: The level of knowledge related to HPV and CC was unexpectedly low in women who had undergone CC. Intuitive educational resources may improve this knowledge, and further cohort studies are warranted.

한국 20대의 비타민 D 결핍 관련요인 분석

주미현(Mi-Hyun Joo),이산휘(San-Hui Lee),이윤경(Yun-Kyung Lee),류소연(So-Yeon Ryu) 한국산학기술학회 2018 한국산학기술학회논문지 Vol.19 No.5

본 연구의 목적은 ‘국민건강영양조사 제 5기(2010-2012)’ 자료를 이용하여 만 20-29세 연령의 한국인에서의 비타민 D 수준과 비타민 D 결핍관련요인을 알아보고자 하였다. ‘국민건강영양조사 제 5기(2010년-2012년) 완료자중에서 비타민 D 결측치가 없는 만 20세 이상 만 29세 미만 1,837명을 대상으로 분석하였다. 사용된 데이터는 가중치가 적용된 복합표본분석을 이용하여 카이제곱검정 및 다중로지스틱 회귀분석으로 분석하였다. 20대의 84.2%가 비타민 D 결핍으로 조사되었으며 여성이 88.6%로 남성 79.4%보다 높은 결핍률을 보였다. 다중 로지스틱 회귀분석 결과, 비타민 D 결핍에 대한 위험도가 여성인 경우(OR 1.84; 95% CI 1.31-2.56), 미혼인 경우(OR 2.12; 95% CI 1.41-3.19), 주관적 건강상태가 나쁨인 경우(OR 1.94; 95% CI 1.16-3.25) 그리고 중등도 이상 신체활동을 하지 않는 경우(OR 3.38; 95% CI 1.85-6.16)에 높았다. 불확실한 미래를 위해 다양한 노력과 활동을 하는 20대의 비타민 D 결핍은 개인적으로나 사회적으로 매우 중요한 건강문제로 영향을 주기때문에 이 시기의 비타민 D 수준에 대한 지속적인 연구가 필요할 것이다. 또한 비타민 D는 햇빛에 노출되는 시간과 신체활동여부와 밀접한 관련이 있는 것으로 나타나 20대의 야외활동 및 중등도 이상의 신체활동을 할 수 있는 학교 및 직장 내 기반시설을 조성하는 등 국가차원에서의 장기적이고 계획적인 노력이 필요하리라고 생각된다. The aim of this study was to investigate vitamin D status and factors associated with vitamin D deficiency among Koreans in their using Korean National Health and Nutrition Examination Survey (KNHANES) V. The subjects were 1,837 people who were 20-29 years old. The data were analyzed by χ² test and multiple logistic regression analysis using weighted composite sample analysis. Vitamin D deficiency was reveled in 84.2% of subjects; 88.6% of women and 79.4% of men showed deficiency. In the multiple logistic regression analysis, the risk for vitamin D deficiency was higher in women (OR 1.84; 95% CI 1.31-2.56), non-married (OR 2.12; 95% CI 1.41-3.19), poor subjective health status (OR 1.94; 95% CI 1.16-3.25), and in the absence of moderate to vigorous physical activity (OR 3.38; 95% CI 1.85-6.16). Continued research on vitamin D levels at this time is needed since vitamin D deficiency among Koreans in their twenties will exacerbate health problems, both individually and socially. In addition, vitamin D has been shown to be closely related to time of exposure to sunlight and physical activity. Therefore, it is thought that long-term and planned efforts should be made at the national level, such as establishing schools and workplaces in which those in their twenties can perform outdoor activities and moderate to vigorous physical activity.