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최확도법을 (最確度法) 이용한 무증상 (無症狀) 정상간기능 (正常肝機能) HBsAg 양성자 간스캔의 감별진단 (鑑別診斷)
윤종만(Chong Mann Yoon),범희승(Hee Seung Bom),류종선(Jong Sun Rew),이성(Sung Lee),윤경환(Kyung Hwan Yoon),김지열(Ji Yeoul Kim) 대한소화기학회 1988 대한소화기학회지 Vol.20 No.2
N/A For the differential diagnosis of asymptomatic HBsAg carrier with normal liver function by the liver scan, authors applied the maximum likelihood method as follows: 1) Ninety-six cases who underwent both peritoneoscopic liver biopsy and liver scan were divided randomly into two groups. In one group scoring table was made and in the other group diagnostic accuracy of the data was evaluated. The diagnostic accuracy in general was 53.2% and those in normal, liver cirrhosis, nonspecific reactive hepatitis, and chronic active hepatitis were 85.7%, 75%, 62.5%, and 12.5%, respectively. 2) Twenty-eight liver scans of aymptomatic HBsAg carrier with normal liver function were revealed to be normal in 23 cases (82.2%) and liver cirrhosis in 5 cases (17.8%). In conclusion the maximum likelihood method was considered to be useful in the differential diagnosis of liver scans. And we recommend a careful evaluation of asymptomatic HBsAg carrier with normal liver function in view of the fact that 17.8% of them was diagnosed as liver cirrhosis in this study.
윤종만(Chong Mann Yoon),유종선(Jong Sun Rew),최성규(Sung Kyu Choi),양대현(Dae Hyun Yang),이숭(Soong Lee),구철(Chull Koo) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.4
N/A Bile duct carcinoma is relatively rare malignancy with an extremely grave prognosis. The case records of 49 patients with primary carcinoma of the bile ducts seen at the Chonnam University Hospital from 1981 to 1988 were reviewed and analyzed. The results were as fo]lows 1) The peak age distribution was in seventh decade and the average age being 61.4 years. The sex ratio of male to female was 1.9:l. 2) In 43 of the 49 patients, anatomic location was extrahepatic bile duct. The most frequently involved site among the extrahepatic bile ducts was common bile duct (38.8%). 3) The most common symptom and sign were RUQ abdominal pain (75.5%), jaundice (89.7%), respectively. 4) Serum alkaline phosphatase and r-GTP were more increased in extrahepatic bile duct carcinoma than intrahepatic bile duct carcinoma. 5) Associated disease were clonorchiasis (12.2%), choledocholithiasis (10.2%), and gall stone (4.0%). 6) The most useful diagnostic modality was percutaneous transhepatic cholangiography and focal stenotic lesions (66.6%) were rnost common. 7) Operability and resectability were 26.5%, 16.3%, respectively. 8) Tubular adenocarcinoma was the most frequent histo]ogic type.
윤종만(Chong Mann Yoon),범희승(Hee Seung Bom),국돈표(don Pio Kook),김성렬(Seong Rhyul Kim),양건호(Keon Ho Yang),김석빈(Suk Bin Kim) 대한소화기학회 1985 대한소화기학회지 Vol.17 No.2
N/A Esophageal carcinomas are relatively rare among those of arising in gastrointestinal tract, but are important because of the high mortality and poor prognosis they have. This report was attempted to deal with an endoscopicopathological evaluation of 114 cases which had been diagnosed as esophageal cancer in the Department of Internal Medicine, Chonnam University Hospital during the period from January 1975 to August 1984. The results were as following 1) In 114 cases of esophageal cancer, male to female ratio was 7.8: 1. The peak age incidence was the 6 th decade with 39.5% 2) The tumors located at the middle one third in 48, at the lower one third in 40, at the cardia in 17, and at the upper one third in 9 cases. 3) Endoscopically, 53 cases were elevated types, 22 cases were stenotic, the remainings were 18 depressed, 15 superficial, and 6 unclassified types in order of frequency. 4) Endoscopic biopsy positive rate was 65%, in 114 cases of esophageal cancer and there was no significant difference in the involved sites but significant difference in the endoscopic tumor types: In elevated types, biopsy positive rate was 81% and in stenotic types 36% 5) Histological classification of the esophageal cancer in our study was squamous cell carcinoma in 56 cases, adenocarcinoma in 14 cases, undifferentiated carcinoma in 3 cases, and mucinous cell carcinoma in 1 case in order of frequency. 6) The histopathological types of the non-malignant cases were normal mucosa in 23 cases (59.5%), inflammation in 8 cases(20%), dysplasia in 5 cases(12.5%), hyperplasia in 2 cases (5.0%), and ulceration in 1 case(2.5%).