운동 프로그램이 비만 청소년의 경동맥 내중막두께와 상완동맥 혈관내피세포 의존성 혈관이완능에 미치는 영향

윤은선 ( Eun Sun Yoon ),정수진 ( Su Jeen Jung ),제세영 ( Sae Young Jae ) 한국운동생리학회 2010 운동과학 Vol.19 No.2

The purpose of this study was to assess the effect of exercise training program on vascular structure and function in obese adolescents. Twenty obese adolescents (age 13-14 years, male, body mass index 30±3 kg/m2) were randomly assigned to an exercise training group (n=10) and a non-exercise control group (n=10). The subjects in the exercise training group performed supervised aerobic exercise programs with moderate intensity for 12 weeks, 60-90 minutes per session, 3 times per week. Brachial artery flow mediated vasodilatation and common carotid artery intima- media thickness(CIMT) were measured using B-mode ultrasound. There were significant decrease in body weight (p=.001), % body fat (p=.004), waist circumference (p=.001) and increase in cardiorespiratory fitness (p=.001) after 12 weeks exercise program. Maximal CIMT(p=.043), but not mean CIMT(p=.220), and brachial artery flow-mediated vasodilation (p=.001) were significantly improved in the exercise group compared with the control group, while lipid profile and insulin resistance were not significantly improved in the exercise group. These data indicate that 12 weeks exercise training program reduced body weight, improved cardiorespiratory fitness and vascular structure/function in obese adolescents.

저항성 운동이 고혈압 전단계 및 고혈압 환자의 24시간 활동성 혈압에 미치는 효과

윤은선 ( Eun Sun Yoon ),정수진 ( Su Jeen Jung ),정솔지 ( Sol Ji Jung ),노동인 ( Dong In Roh ),제세영 ( Sae Young Jae ) 한국운동생리학회 2010 운동과학 Vol.19 No.2

This study was to investigate the effects of resistance exercise in untreated pre and hypertensive subjects. Twenty-three subjects(62±6yrs) with pre and hypertension were participated in the study. Subjects were randomly assigned to an exercise group(n=11) and a control group(n=6). Exercise group was performed the supervised resistance exercise program with low to moderate intensity(40~60% of 1 RM), 12 repetitions, 2sets, 3 times per week, for 12weeks. Body composition, lipid profiles, insulin resistance, cardiorespiratory fitness, 1 RM test, clinical blood pressure and 24 hour ambulatory pressure were measured at baseline and after 12 weeks intervention. Chest press of 1 RM test was significantly increased in exercise group compared with control group(p=0.020). There were no significant changes in body composition, lipid profiles, insulin resistance, and cardiorespiratory fitness. Clinical blood pressure tended to decrease in exercise group, but 24 hour ambulatory blood pressure was not changed. In conclusion, resistance exercise did not improve clinical and 24 hour ambulatory blood pressure in untreated pre and hypertensive subjects.

노인여성에서 심폐기능과 혈관 경직도의 상관관계

윤은선 ( Eun Sun Yoon ),정수진 ( Su Jeen Jung ),제세영 ( Sae Young Jae ) 한국운동생리학회 2009 운동과학 Vol.18 No.3

일시적 저항성 운동이 냉압박 검사에 대한 심혈관 재반응 완화에 미치는 영향

윤은선 ( Eun Sun Yoon ),박수현 ( Soo Hyun Park ),이용희 ( Yong Hee Lee ),제세영 ( Sae Young Jae ) 대한스포츠의학회 2016 대한스포츠의학회지 Vol.34 No.1

Increased cardiovascular reactivity to sympathetic challenge is associated with increased risk of hypertension and cardiovascular disease. Acute aerobic exercise blunts stress related cardiovascular reactivity, but whether acute resistance exercise attenuates cardiovascular reactivity is unknown. We tested the hypothesis that acute resistance exercise will attenuate hemodynamic reactivity to a cold pressor test in healthy adults. Using a randomized cross-over trial, 20 healthy adults (9 males, 11 females; age, 26±5 years; body mass index, 23.85±3.19 kg/m2) completed two testing sessions, separated by 1 week. Sessions consisted of either a control condition or an acute resistance exercise prior to cold pressor testing (two sets, eight exercises, 40%-60% of 1 repetition maximum for upper and lower extremity). Blood pressure and heart rate measured at baseline, 30 seconds, and 120 seconds during a 3-minute cold pressor test (ice water, 4oC), and 30 seconds and 120 seconds post-cold pressor testing, respectively. During the cold pressor test, there were significant increases in blood pressures and heart rate (p<0.05) in both groups. However, acute resistance exercise attenuated increases in systolic blood pressure, but not heart rate, compared with the control (all p<0.05 for interact effects). These findings show that the cold pressor test significantly increases blood pressures and heart rate in healthy adults, but an acute bout of resistance exercise attenuated the hemodynamic response to the cold pressor test. Therefore, resistance exercise may have a favorable effect on cardiovascular reactivity to sympathetic activation in healthy adults.

국민체력100 유아기 체력측정도구의 측정-재측정 신뢰도 연구

윤은선 ( Eun Sun Yoon ),송홍선 ( Hong Sun Song ),한태경 ( Tea-kyung Han ),이혜수 ( Hye Su Lee ),김태완 ( Tea Wan Kim ),박수현 ( Soo Hyun Park ) 한국운동생리학회 2021 운동과학 Vol.30 No.1

PURPOSE: Physical fitness is a powerful health marker for the well-being of children and adolescence as well as a vital predictor of health later in life. In this regard, the assessment of physical fitness in young people is important from a clinical and public health point of view. The purpose of this study was to examine the test-retest reliability of a National Fitness Award Battery for preschool children. METHODS: A total of 141 preschoolers aged 4-6 years participated in this study. Anthropometry, muscle strength, endurance, flexibility, cardiorespiratory fitness, balance, speed, agility and coordination were assessed by measuring or testing their height and weight, handgrip, curl-up, sit and reach, 10 m shuttle run, one leg stand, standing long jump, 5 m×4 shuttle run, ball throw, ball kick and button-pushing respectively. Each test was performed twice with a two-week interval and test-retest reliability was evaluated using intraclass correlation coefficients (ICC). Bland-Altman plots were used to measure agreement. RESULTS: The results indicated that the test items were excellently reliable (height, weight, handgrip, curl-up, sit and reach, 10 m shuttle run, standing long jump, 5 m×4 shuttle run and button-pushing) except for one leg stand, ball throw and ball kick tests. CONCLUSIONS: National Fitness Award Battery for preschool children is a reliable tool to assess their physical fitness yet one leg stand, and ball throw, ball kick tests showed poor reliability. In order to find substitute items, further study will be required.

척수장애인에서 활동적 비디오 게임을 활용한 신체활동이 고지방 식이 후 혈관기능 감소에 미치는 영향

윤은선 ( Eun Sun Yoon ),김현정 ( Hyun Jeong Kim ),추진아 ( Jina Choo ),박경희 ( Kyung Hee Park ),제세영 ( Sae Young Jae ) 대한스포츠의학회 2017 대한스포츠의학회지 Vol.35 No.3

Endothelial dysfunction induced with a high-fat meal may be attenuated with an exercise in abled bodies individuals. Exergaming may be an exercise type applicable for disabled bodied individuals. We tested the hypothesis that an acute bout of exergaming following a high-fat meal would decrease postprandial lipemia, and endothelial dysfunction among individuals with spinal cord injury. Forty participants (age, 41±8 years; 24 males) were randomly assigned to either an exergaming group (n=20) or control group with seated rest (n=20) following a high-fat meal. Hemodynamic and blood parameters and flow-mediated vasodilation (FMD) as an index of endothelial function were measured at baseline and 4 hours after a high-fat meal. In half an hour following a high-fat meal, the exergaming group performed 50 minutes of moderate intensity active video games (Nintendo Wii Sports: boxing, tennis). Levels of blood triglycerides increased in both group (p<0.05) following high-fat meal. FMD significantly decreased in the control group (10.4%±4.9% to 7.9%±4.4%) but significantly increased in the exergaming group (10.9%±5.3% to 12.3%±5.3%), with a significant interaction (p=0.004). These results show that a high-fat meal causes endothelial dysfunction in persons with spinal cord injury, but endothelial dysfunction following a high-fat meal was attenuated by an acute bout of exergaming regardless of postprandial lipemia. Therefore, exergaming for individuals with spinal cord injury may have a cardioprotective effect from postprandial endothelial dysfunction induced with an exposure of a high-fat meal.

허혈성 저처치가 일시적 저항성 운동 후 동맥경직도에 미치는 영향

윤은선 ( Eun Sun Yoon ),김연욱 ( Yun Wook Kim ),카녹완분사왓 ( Kanokwan Bunsawat ),제세영 ( Sae Young Jae ) 대한스포츠의학회 2024 대한스포츠의학회지 Vol.42 No.3

Purpose: Whether remote ischemic preconditioning (RIPC), repeated bouts of ischemia and reperfusion, prevents arterial stiffening following an acute high-intensity resistance exercise (RE) is unknown. We tested the hypothesis that RIPC would attenuate arterial stiffening following acute high-intensity RE in healthy adults. Methods: Using a randomized, single-blind, sham-controlled, crossover design, 14 adults (eight males and six females; age, 26±1 years) completed two testing sessions, separated by 1 week. Sessions consisted of either an RIPC intervention (4×5 minutes, 220 mm Hg, bilateral arm occlusion) or a sham condition (4×5 minutes, 20 mm Hg, bilateral arm occlusion) prior to RE (two sets, eight exercises, 80% of one repetition maximum). Carotid-femoral pulse wave velocity (cfPWV) and augmentation index at 75 beats per minute (AIx@75bpm) as indices of arterial stiffness and blood pressures were measured at baseline, immediately after RE, and 30 minutes, 1 hour after RE using an applanation tonometry. Results: Brachial and central systolic blood pressures and cfPWV increased from baseline (p<0.05), with no trial differences. No differences were observed for heart rate, brachial and central diastolic blood pressures, and AIx@75bpm. Conclusion: These findings demonstrate that acute RE increased arterial stiffness, but this increase was not attenuated by RIPC when applied before RE. This suggests that RIPC prior to an acute bout of high-intensity RE may not protect against RE-induced arterial stiffening.

Clinical Article : 일회성 저항성 운동이 허혈 재관류 손상에 의한 대혈관 및 미세혈관 기능에 미치는 영향

윤은선 ( Eun Sun Yoon ),박수현 ( Soo Hyun Park ),이용희 ( Yong Hee Lee ),( Chong Lee ),제세영 ( Sae Young Jae ) 대한스포츠의학회 2013 대한스포츠의학회지 Vol.31 No.2

Ischemia reperfusion injury (IRI) leads to a temporary decrease in macrovascular function, but whether IRI causes microvascular dysfunction is not known. Resistance exercise involves muscular contractions that can make downstream tissues ischemic and may ischemic preconditioning the vasculature against endothelial IRI. We tested the hypothesis that an acute resistance exercise prior to IRI would prevent or attenuate IRI induced macro- and microvascular dysfunction in healthy young adults. Nineteen healthy young subjects (age 22±2 years) were randomly assigned to either a resistance exercise group (n=10) as a model to produce ischemic preconditioning or a control group (n=9). The resistance exercise was performed eight types of systemic resistance exercise. Ischemia was induced by inflating a cuff placed around the upper arm to 200 mm Hg for 20 minutes. carotid-femoral pulse wave velocity (cfPWV) as index of macrovascular function and reactive hyperemia index (RHI) using by fingertip arterial tonometry as index of microvascular function were measured at baselines and 15 and 30 minutes after ischemia reperfusion injury. cfPWV was increased in control group but decreased in resistance exercise group following IRI. There was a significant interaction effect between resistance exercise group and control group for cfPWV (p=0.022). The RHI was unaffected following IRI and also unchanged by a resistance exercise. These findings show that ischemia reperfusion caused macrovascular dysfunction but not microvascular dysfunction. However, this macrovascular dysfunction following IRI was not shown in the resistance exercise group. Thus, an acute bout of resistance exercise prior to ischemia may prevent against ischemia reperfusion injury induced macrovascular dysfunction.

직무스트레스, 심폐체력, 심혈관계질환 위험인자와의 관련성

윤은선 ( Eun Sun Yoon ),제세영 ( Sae Young Jae ) 대한스포츠의학회 2017 대한스포츠의학회지 Vol.35 No.1

Occupational stress is associated with increased risk of cardiovascular disease (CVD), while cardiorespiratory fitness (CRF) is associated with decreased risk of CVD. We tested the hypothesis that high occupational stress would be associated with increased cardiovascular risk profiles, but CRF may attenuate this association. We conducted a cross-sectional analysis in 70 healthy office workers (male, 28; female, 42; mean age, 38±8 years). Occupational stress was assessed using a validated self-reported questionnaire. Total CVD risk score (sum of z-standardized residuals) was calculated by blood pressure, body mass index, lipid profiles and glucose. CRF was estimated by predicted equation during maximal treadmill exercise test. The results showed that an interpersonal conflict as an index of occupational stress was positively correlated with cardiovascular risk score (r=0.43, p<0.05). In contrast, Higher CRF was associated with lower occupational climate (r=-0.25, p<0.05) and total occupational stress score (r=-0.29, p<0.05). The total CVD risk score was similar between group with high stress but high fitness and group with low stress and high fitness (p>0.05). Furthermore, Participants with high stress but high CRF had lower cardiovascular risk score than those with high stress but low CRF (p<0.05). In conclusion, occupational stress is associated with an increased CVD risk, but CRF attenuated this association in office worker with increased occupational stress.

일회 수영운동의 건강한 성인의 혈압과 동맥경직도에 미치는 영향

윤은선 ( Eun Sun Yoon ),이선주 ( Seon Ju Lee ),제세영 ( Sae Young Jae ) 한국운동생리학회 2012 운동과학 Vol.21 No.1

Swimming is one of the aerobic exercise, most recommended forms for blood pressure and body weight control. Although the hemodynamic response to swimming may be expected to be different from the re5IXJnse to land-based exercise there is little information on the effects of swimming exercise on arterial stiffness. The purpose of this study was to compare the acute effects of swimming and walking as a control exercise on arterial stiffness in young subjects. Twenty-six healthy subjects (age 21±2 yrs and body mass index 22±2 kg/m2) were randomly assigned to either an acute bout of swimming exercise (n=14, 1,500 m for male and 1,200 m for female at 60~70% of heart rate reserve) or walking exercise (n=12, 30-minute at same intensity with swimming). Carotid-femoral pulse wave velocity and aortic augmentation index as indices of aortic stiffness were measured using applanation tonometry. All variables were measured at baseline, 20 and 40 minutes after each exercise. Walking exercise significantly decreased systolic and diastolic blood pressure (p<.05), but there was no significant changes following the swimming exercise. Aortic augmentation index was significantly increased following the swimming exercise 20 minutes post exercise (-8.5±11.3 to -3.7±l0.7%, p<.05), but did not significantly changes following the walking exercise. Carotid-femoral pulse wave velocity was increased after swimming exercise (6.75±0.89 to 6.98±0.66 m/s) and decreased after walking exercise (6.28±0.61 to 6.12±0.57 m/s) at 20 minutes post exercise, but changes were not statistically significant These findings suggest that relative to moderate intensity walking, acute swimming less decreases blood pressure and arterial stiffness. Further studies are needed to clarify the effects of long tem swimming exercise on arterial stiffness.