노인여성에서 심폐기능과 혈관 경직도의 상관관계

윤은선 ( Eun Sun Yoon ),정수진 ( Su Jeen Jung ),제세영 ( Sae Young Jae ) 한국운동생리학회 2009 운동과학 Vol.18 No.3

저항성 운동이 고혈압 전단계 및 고혈압 환자의 24시간 활동성 혈압에 미치는 효과

윤은선 ( Eun Sun Yoon ),정수진 ( Su Jeen Jung ),정솔지 ( Sol Ji Jung ),노동인 ( Dong In Roh ),제세영 ( Sae Young Jae ) 한국운동생리학회(구-한국운동과학회) 2010 운동과학 Vol.19 No.2

본 연구에서는 약물 치료를 받고 있지 않는 고혈압 전단계 및 고혈압 환자를 대상으로 저항성 운동이 24시간 활동성 혈압에 미치는 효과에 대해 알아보고자 하였다. 연구 대상은 약물을 복용하고 있지 않은 고혈압 전단계와 고혈압 환자를 대상으로 하였으며 평균 나이는 62±6세였다. 모집된 총 17명을 대상으로 운동군(n=11)과 통제군(n=6)으로 무선 배정하였다. 운동군은 1RM의 40~60% 강도로 총 9종목의 저항성 운동을 12회 반복횟수로 2세트, 주 3회, 12주간 실시하였다. 통제군은 동일기간 저항성 운동에 참여하지 않았으며, 평소 생활습관을 유지하도록 하였다. 운동군과 통제군 모두 운동 프로그램 참가 전, 후에 신체계측, 최대근력검사, 운동부하검사, 혈중지질 및 인슐린 저항성, 임상혈압 및 24시간 활동성 혈압을 측정하였다. 연구 결과, 최대근력 검사 중 chest press가운동군이 통제군에 비해 유의하게 증가하였다(p=0.020). 그러나 신체계측 지표, 혈중지질 및 인슐린 저항성, 최대산소섭취량에서 시기와 집단간의 유의한 상호작용 효과가 나타나지 않았다. 상완동맥 수축기혈압과 이완기 혈압 모두 감소하였지만 통계적으로 유의하지 않았으며, 24시간 활동성 혈압은 일일평균혈압, 주간혈압, 수면시 혈압 모두 통계적으로 유의한 변화를 보이지 않았다. 결론적으로 본 연구 에서는 저항성 운동이 고혈압 환자의 임상혈압과 24시간 활동성 혈압을 유의하게 개선시키지 못하였다. This study was to investigate the effects of resistance exercise in untreated pre and hypertensive subjects. Twenty-three subjects(62±6yrs) with pre and hypertension were participated in the study. Subjects were randomly assigned to an exercise group(n=11) and a control group(n=6). Exercise group was performed the supervised resistance exercise program with low to moderate intensity(40~60% of 1 RM), 12 repetitions, 2sets, 3 times per week, for 12weeks. Body composition, lipid profiles, insulin resistance, cardiorespiratory fitness, 1 RM test, clinical blood pressure and 24 hour ambulatory pressure were measured at baseline and after 12 weeks intervention. Chest press of 1 RM test was significantly increased in exercise group compared with control group(p=0.020). There were no significant changes in body composition, lipid profiles, insulin resistance, and cardiorespiratory fitness. Clinical blood pressure tended to decrease in exercise group, but 24 hour ambulatory blood pressure was not changed. In conclusion, resistance exercise did not improve clinical and 24 hour ambulatory blood pressure in untreated pre and hypertensive subjects.

국민체력100 유아기 체력측정도구의 측정-재측정 신뢰도 연구

윤은선 ( Eun Sun Yoon ),송홍선 ( Hong Sun Song ),한태경 ( Tea-kyung Han ),이혜수 ( Hye Su Lee ),김태완 ( Tea Wan Kim ),박수현 ( Soo Hyun Park ) 한국운동생리학회(구 한국운동과학회) 2021 운동과학 Vol.30 No.1

PURPOSE: Physical fitness is a powerful health marker for the well-being of children and adolescence as well as a vital predictor of health later in life. In this regard, the assessment of physical fitness in young people is important from a clinical and public health point of view. The purpose of this study was to examine the test-retest reliability of a National Fitness Award Battery for preschool children. METHODS: A total of 141 preschoolers aged 4-6 years participated in this study. Anthropometry, muscle strength, endurance, flexibility, cardiorespiratory fitness, balance, speed, agility and coordination were assessed by measuring or testing their height and weight, handgrip, curl-up, sit and reach, 10 m shuttle run, one leg stand, standing long jump, 5 m×4 shuttle run, ball throw, ball kick and button-pushing respectively. Each test was performed twice with a two-week interval and test-retest reliability was evaluated using intraclass correlation coefficients (ICC). Bland-Altman plots were used to measure agreement. RESULTS: The results indicated that the test items were excellently reliable (height, weight, handgrip, curl-up, sit and reach, 10 m shuttle run, standing long jump, 5 m×4 shuttle run and button-pushing) except for one leg stand, ball throw and ball kick tests. CONCLUSIONS: National Fitness Award Battery for preschool children is a reliable tool to assess their physical fitness yet one leg stand, and ball throw, ball kick tests showed poor reliability. In order to find substitute items, further study will be required.

일회 수영운동의 건강한 성인의 혈압과 동맥경직도에 미치는 영향

윤은선 ( Eun Sun Yoon ),이선주 ( Seon Ju Lee ),제세영 ( Sae Young Jae ) 한국운동생리학회(구-한국운동과학회) 2012 운동과학 Vol.21 No.1

수영은 대표적인 유산소 운동으로써 혈압 및 체중관리를 위해 권장되고 있다. 수영운동은 지상운동과 다른 혈액동역학적 반응을 나타내지만, 아직 수영운동의 혈판 기능 개선에 미치는 영향에 관한 연구는 부족하다. 본 연구에서는 건강한 성인을 대상으로 일회 수영 운동과 걷기 운동 후 혈압과 동맥경직도의 변화를 비교해 보고자 하였다. 건강한 성인 남녀 26명(평균나이: 21±2세, 체질량지수: 22±2 kg/m2)을 수영운동 그룹(n=12)과 걷기 운동 그룹(n=12)에 무선 배정하였다. 수영운동은 예비심박수 60-70% 강도로 남자 1,500 m, 여자 1,200m를 수행하였으며, 걷기운동은 수영운동과 통일강도로 30분간 실시하였다. 동맥경직도 지표로서 경동맥-대퇴동맥 맥파전파속도, 대통맥파형증폭지수를 측정하였으며, 모든 종속변인들은 각각의 운동전, 운동 후 20분, 운동 후 40분에 측정하였다. 걷기 운동 후 수축기 혈압과 이완기 혈압은 감소하였지만(p<.05), 수영운동 후에는 유의한 변화가 나타나지 않았다. 심박수 75박에서의 대동맥 파형증폭지수의 경우 수영운동 후 20분·에 유의하게 증가하였으나(-8.5土11.3 to -3.7±10.7%, p<.05), 걷기 운동 후에는 통계적으로 유의한 변화를 보이지 않았다(-7.17±11.19 to -5.54±l0.29%, p>,05). 경동맥-대퇴동맥 맥파전파속도의 경우 운동 후 20분에 수영운동 그룹에서는 중가하고 걷기 운동 그룹에서는 감소하였으나 통계적으로 유의한 차이를 보이지는 않았다. 이상의 결과를 종합해 보면, 걷기 운동에 비해 일회 수영운동은 혈압과 동맥경직도를 덜 감소시켰으며, 수영운동이 동맥경직도에 미치는 영향을 명확히 밝히기 워해서는 추후 장기간의 트레이닝 연구가 필요할 것으로 사료된다. Swimming is one of the aerobic exercise, most recommended forms for blood pressure and body weight control. Although the hemodynamic response to swimming may be expected to be different from the re5IXJnse to land-based exercise there is little information on the effects of swimming exercise on arterial stiffness. The purpose of this study was to compare the acute effects of swimming and walking as a control exercise on arterial stiffness in young subjects. Twenty-six healthy subjects (age 21±2 yrs and body mass index 22±2 kg/m2) were randomly assigned to either an acute bout of swimming exercise (n=14, 1,500 m for male and 1,200 m for female at 60~70% of heart rate reserve) or walking exercise (n=12, 30-minute at same intensity with swimming). Carotid-femoral pulse wave velocity and aortic augmentation index as indices of aortic stiffness were measured using applanation tonometry. All variables were measured at baseline, 20 and 40 minutes after each exercise. Walking exercise significantly decreased systolic and diastolic blood pressure (p<.05), but there was no significant changes following the swimming exercise. Aortic augmentation index was significantly increased following the swimming exercise 20 minutes post exercise (-8.5±11.3 to -3.7±l0.7%, p<.05), but did not significantly changes following the walking exercise. Carotid-femoral pulse wave velocity was increased after swimming exercise (6.75±0.89 to 6.98±0.66 m/s) and decreased after walking exercise (6.28±0.61 to 6.12±0.57 m/s) at 20 minutes post exercise, but changes were not statistically significant These findings suggest that relative to moderate intensity walking, acute swimming less decreases blood pressure and arterial stiffness. Further studies are needed to clarify the effects of long tem swimming exercise on arterial stiffness.

직무스트레스, 심폐체력, 심혈관계질환 위험인자와의 관련성

윤은선 ( Eun Sun Yoon ),제세영 ( Sae Young Jae ) 대한스포츠의학회 2017 대한스포츠의학회지 Vol.35 No.1

Occupational stress is associated with increased risk of cardiovascular disease (CVD), while cardiorespiratory fitness (CRF) is associated with decreased risk of CVD. We tested the hypothesis that high occupational stress would be associated with increased cardiovascular risk profiles, but CRF may attenuate this association. We conducted a cross-sectional analysis in 70 healthy office workers (male, 28; female, 42; mean age, 38±8 years). Occupational stress was assessed using a validated self-reported questionnaire. Total CVD risk score (sum of z-standardized residuals) was calculated by blood pressure, body mass index, lipid profiles and glucose. CRF was estimated by predicted equation during maximal treadmill exercise test. The results showed that an interpersonal conflict as an index of occupational stress was positively correlated with cardiovascular risk score (r=0.43, p<0.05). In contrast, Higher CRF was associated with lower occupational climate (r=-0.25, p<0.05) and total occupational stress score (r=-0.29, p<0.05). The total CVD risk score was similar between group with high stress but high fitness and group with low stress and high fitness (p>0.05). Furthermore, Participants with high stress but high CRF had lower cardiovascular risk score than those with high stress but low CRF (p<0.05). In conclusion, occupational stress is associated with an increased CVD risk, but CRF attenuated this association in office worker with increased occupational stress.

척수장애인에서 활동적 비디오 게임을 활용한 신체활동이 고지방 식이 후 혈관기능 감소에 미치는 영향

윤은선 ( Eun Sun Yoon ),김현정 ( Hyun Jeong Kim ),추진아 ( Jina Choo ),박경희 ( Kyung Hee Park ),제세영 ( Sae Young Jae ) 대한스포츠의학회 2017 대한스포츠의학회지 Vol.35 No.3

Endothelial dysfunction induced with a high-fat meal may be attenuated with an exercise in abled bodies individuals. Exergaming may be an exercise type applicable for disabled bodied individuals. We tested the hypothesis that an acute bout of exergaming following a high-fat meal would decrease postprandial lipemia, and endothelial dysfunction among individuals with spinal cord injury. Forty participants (age, 41±8 years; 24 males) were randomly assigned to either an exergaming group (n=20) or control group with seated rest (n=20) following a high-fat meal. Hemodynamic and blood parameters and flow-mediated vasodilation (FMD) as an index of endothelial function were measured at baseline and 4 hours after a high-fat meal. In half an hour following a high-fat meal, the exergaming group performed 50 minutes of moderate intensity active video games (Nintendo Wii Sports: boxing, tennis). Levels of blood triglycerides increased in both group (p<0.05) following high-fat meal. FMD significantly decreased in the control group (10.4%±4.9% to 7.9%±4.4%) but significantly increased in the exergaming group (10.9%±5.3% to 12.3%±5.3%), with a significant interaction (p=0.004). These results show that a high-fat meal causes endothelial dysfunction in persons with spinal cord injury, but endothelial dysfunction following a high-fat meal was attenuated by an acute bout of exergaming regardless of postprandial lipemia. Therefore, exergaming for individuals with spinal cord injury may have a cardioprotective effect from postprandial endothelial dysfunction induced with an exposure of a high-fat meal.

운동 프로그램이 비만 청소년의 경동맥 내중막두께와 상완동맥 혈관내피세포 의존성 혈관이완능에 미치는 영향

윤은선 ( Eun Sun Yoon ),정수진 ( Su Jeen Jung ),제세영 ( Sae Young Jae ) 한국운동생리학회(구-한국운동과학회) 2010 운동과학 Vol.19 No.2

본 연구의 목적은 비만 청소년을 대상으로 운동 프로그램이 혈관의 구조와 기능에 미치는 영향을 알아보는데 있다. 비만 남자 청소년(연령 13-14세, 평균 체질량지수 30±3 kg/m2) 총 20명을 모집하여 운동군(n=10)과 통제군(n=10)으로 무선 배정하였다. 운동군은 중정도의 운동강도로 주 3회, 1회 운동 시간 60~90분의 운동을 12주간 실시하였으며, 통제군은 동일 기간 평소 생활습관을 유지하도록 하였다. 운동군과 통제군 모두 운동 참여 전, 후에 체성분 검사, 혈중지질, 인슐린 저항성, 심폐체력, 혈관내피세포 의존성 혈관이완능, 경동맥 내중막 두께를 측정하였다. 연구 결과, 운동 후 운동군에서 체중(p=.001), 체지방율(p=.004), 허리둘레(p=.001)가 유의하게 감소하였으며, 심폐체력(p=.001)이 유의하게 증가하였다. 또한 경동맥 내중막 두께 최대값(p=.043)이 유의하게 감소하였고, 상완동맥 혈관 내피세포 의존성 혈관이완능(p=.001)이 유의하게 증가하였다. 그러나 혈중 지질과 인슐린 저항성은 유의한 개선 효과를 나타내지 않았다. 이상의 결과를 종합해 보면, 비만 청소년을 대상으로 12주간의 운동 참여는 체성분 개선 및 심폐체력 향상과 더불어 혈관구조와 기능에 긍정적인 효과를 가져왔다. The purpose of this study was to assess the effect of exercise training program on vascular structure and function in obese adolescents. Twenty obese adolescents (age 13-14 years, male, body mass index 30±3 kg/m2) were randomly assigned to an exercise training group (n=10) and a non-exercise control group (n=10). The subjects in the exercise training group performed supervised aerobic exercise programs with moderate intensity for 12 weeks, 60-90 minutes per session, 3 times per week. Brachial artery flow mediated vasodilatation and common carotid artery intima- media thickness(CIMT) were measured using B-mode ultrasound. There were significant decrease in body weight (p=.001), % body fat (p=.004), waist circumference (p=.001) and increase in cardiorespiratory fitness (p=.001) after 12 weeks exercise program. Maximal CIMT(p=.043), but not mean CIMT(p=.220), and brachial artery flow-mediated vasodilation (p=.001) were significantly improved in the exercise group compared with the control group, while lipid profile and insulin resistance were not significantly improved in the exercise group. These data indicate that 12 weeks exercise training program reduced body weight, improved cardiorespiratory fitness and vascular structure/function in obese adolescents.

일시적 저항성 운동이 냉압박 검사에 대한 심혈관 재반응 완화에 미치는 영향

윤은선 ( Eun Sun Yoon ),박수현 ( Soo Hyun Park ),이용희 ( Yong Hee Lee ),제세영 ( Sae Young Jae ) 대한스포츠의학회 2016 대한스포츠의학회지 Vol.34 No.1

Increased cardiovascular reactivity to sympathetic challenge is associated with increased risk of hypertension and cardiovascular disease. Acute aerobic exercise blunts stress related cardiovascular reactivity, but whether acute resistance exercise attenuates cardiovascular reactivity is unknown. We tested the hypothesis that acute resistance exercise will attenuate hemodynamic reactivity to a cold pressor test in healthy adults. Using a randomized cross-over trial, 20 healthy adults (9 males, 11 females; age, 26±5 years; body mass index, 23.85±3.19 kg/m2) completed two testing sessions, separated by 1 week. Sessions consisted of either a control condition or an acute resistance exercise prior to cold pressor testing (two sets, eight exercises, 40%-60% of 1 repetition maximum for upper and lower extremity). Blood pressure and heart rate measured at baseline, 30 seconds, and 120 seconds during a 3-minute cold pressor test (ice water, 4oC), and 30 seconds and 120 seconds post-cold pressor testing, respectively. During the cold pressor test, there were significant increases in blood pressures and heart rate (p<0.05) in both groups. However, acute resistance exercise attenuated increases in systolic blood pressure, but not heart rate, compared with the control (all p<0.05 for interact effects). These findings show that the cold pressor test significantly increases blood pressures and heart rate in healthy adults, but an acute bout of resistance exercise attenuated the hemodynamic response to the cold pressor test. Therefore, resistance exercise may have a favorable effect on cardiovascular reactivity to sympathetic activation in healthy adults.

Clinical Article : 일회성 저항성 운동이 허혈 재관류 손상에 의한 대혈관 및 미세혈관 기능에 미치는 영향

윤은선 ( Eun Sun Yoon ),박수현 ( Soo Hyun Park ),이용희 ( Yong Hee Lee ),( Chong Lee ),제세영 ( Sae Young Jae ) 대한스포츠의학회 2013 대한스포츠의학회지 Vol.31 No.2

Ischemia reperfusion injury (IRI) leads to a temporary decrease in macrovascular function, but whether IRI causes microvascular dysfunction is not known. Resistance exercise involves muscular contractions that can make downstream tissues ischemic and may ischemic preconditioning the vasculature against endothelial IRI. We tested the hypothesis that an acute resistance exercise prior to IRI would prevent or attenuate IRI induced macro- and microvascular dysfunction in healthy young adults. Nineteen healthy young subjects (age 22±2 years) were randomly assigned to either a resistance exercise group (n=10) as a model to produce ischemic preconditioning or a control group (n=9). The resistance exercise was performed eight types of systemic resistance exercise. Ischemia was induced by inflating a cuff placed around the upper arm to 200 mm Hg for 20 minutes. carotid-femoral pulse wave velocity (cfPWV) as index of macrovascular function and reactive hyperemia index (RHI) using by fingertip arterial tonometry as index of microvascular function were measured at baselines and 15 and 30 minutes after ischemia reperfusion injury. cfPWV was increased in control group but decreased in resistance exercise group following IRI. There was a significant interaction effect between resistance exercise group and control group for cfPWV (p=0.022). The RHI was unaffected following IRI and also unchanged by a resistance exercise. These findings show that ischemia reperfusion caused macrovascular dysfunction but not microvascular dysfunction. However, this macrovascular dysfunction following IRI was not shown in the resistance exercise group. Thus, an acute bout of resistance exercise prior to ischemia may prevent against ischemia reperfusion injury induced macrovascular dysfunction.

청감실험을 통한 철도소음의 자율신경 및 심혈관계통 영향도 연구

이재관(Jae Kwan Lee),윤은선(Eun Sun Yoon),장채미(Chae Mi Jang),제세영(Sae Young Jae),장서일(Seo-Il Chang) 한국소음진동공학회 2016 한국소음진동공학회 학술대회논문집 Vol.2016 No.4

Traffic noise is the biggest part of the environmental noise. Railway noise is better associated with hypertension and adverse cardiovascular events than road traffic noise, but the underlying mechanisms remain unclear. We investigated the hypothesis that exposure to acute railway noise would the unfavorable effect of cardiovascular and autonomic system in healthy young subjects. Using a randomized, sham-controlled cross-over design, ten subjects were assigned to receive either an exposure to high speed train noise (84dB) for 30 minutes or a control condition (non noise), separated by two days. Blood pressure, heart rate, augmentation index and heart rate variability as indices of cardiovascular and autonomic system function were measured at baseline, during, and recovery from two trials. The results show that exposure to acute railway noise significantly increased diastolic blood pressure and augmentation index, which may cause of adverse cardiovascular effects.