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폐의 환기 - 관류 불균형 측정을 위한 특이 확산기능의 이용
김승호(Seung Ho Kim),윤덕경(Duk Kyung Yun),이승주(Seung Ju Lee),박인원(In Won Park),최병휘(Byoung Whui Choi),허성호(Sung Ho Hue),서승천(Seung Cheon Seo) 대한내과학회 1989 대한내과학회지 Vol.37 No.1
N/A To investigate the ventilation-perfusion inequality caused by height change and smoking, we measured the routine conventional pulmonary function test and diffusing capacity by the single breath mentod in 36 smoking healthy men (>11/2 pack/year) and 29 nonsmoking healthy men. The results were as follows: 1) In nonsmokers, an increase in height significantly decreased the specific diffusing capacity (p<0.05) but did not affect diffusing capacity (p>0.05). 2) The specific diffusing capacity significantly decreased in smokers compared to nonsmokers (p<0.01) but diffusing capacity and FEF 25~75% did not. So we suggest that specific diffusing capacity will be a more useful parameter than diffusing capacity and FEF 25~75% to detect ventilation-perfusion inequality disorders in asymptomatic patients with small airway diseases.