매독진의 병리조직학적 고찰

김희옥(Hee Ok Kim),유희준(Hee Joon Yu),손숙자(Sook Ja Son),유태연(Tae Yun Yoo) 대한피부과학회 1993 대한피부과학회지 Vol.31 No.2

Background : The differentiation of syphilids from other skin decreases is frequently difficult due to considerable variations of clinical and histologic pattern. The most common histologic changes in secondary syphilis are swelling & proliferation of endothelial cells and the presence of a perivascular infiltrate containing plasmia cells. But often, these findings are absert or inconspicuous. Objectlve : We examined the histopathologic findings of secondary syphilis in relation to the clinical types of the skin lesion. Methods : 36 biopsy specimens from twenty-nine serologically and clinically confirmed cases of secondary syphilis (15 macules, 8 papules, 2 condylomata latas and 11 papulosquamous lesions) were examined. Raeults : The histopath,ologic findings of secondary syphilis showed comparative differences according to the clinical types of the skin lesion. The plasms cell infltrates were absent or sparse in 14 csses(39%) and the plasma cell infiltration was significantly correhted with the age of skin lesions(p=0.02197). Vascular changes were seen in 32 cases (89%), but the incidence of endothelial proliferation was less(25%). Conclvsion : This study demonstrates the histopathologic findirigs of secondary syphilis in accordance to the clinical morphology of the eruption and thus, help to differentiate syphilids from other skin diseases. (Kor J Dermatol 1993; 31(2): 197-203)

Livedo Vasculitis

홍성우(Sung Woo Hong),이창우(Chang Woo Lee),김중환(Joong Hwan Kim),유태연(Tae Yun Yoo) 대한피부과학회 1983 대한피부과학회지 Vol.21 No.5

Livedo vasculitis or vasculitis of atrophie blanche is a clinical entity which can be distinguished from cutaneous vasculitis by distinctive pathology and immunopathologic study. A 18-year-old female with erythematous, telangiectatic, purpuric or hyperpigmented patches, intermingled with white atrophic ivory patches on her legs of 3 years duration was seen in June 3, 1982. The histologic examination of an atrophic patch showed proliferation and occlusion of blood vessels in the upper dermis with patchy atrophy of the epidermis. The immunopatbologic features of an atrophic patch revealed deposits of IgM, Ca and fibrin as a definitive immunofluorescence vessel pattern. This suggests that the livedo va.sculitis or vasculitis of atrophie blanche may he considered one of the immune vasculitides. This patient had received aspirin and persantine for 4 months, and moderate therapeutic effects could be noticed.

천포창 초기병변에 대한 고찰

양홍윤(Hong Yoon Yang),이창우(Chang Woo Lee),김영태(Young Tae Kim),김재홍(Jae Hong Kim),강형재(Hyung Jai Kang),김원석(Won Suk Kim),유태연(Tae Yun Yoo),김중환(Joong Hwang Kim) 대한피부과학회 1989 대한피부과학회지 Vol.27 No.3

Among 13 patients with pemphigus : 8 of pemphigus vulgaris(PV), 4 of pemphigus foliaceus(PF), l of pemphigus erythematosus(PE), we have examined the sites of early lesions and the clinical appearances of the skin lesions. The most common site of the early lesions in PV was the oral mucosa, however, in PF and PE the face was affected first. The clinical appearances of the early lesions were flaccid bullae, erythematous papules and eczematoid patches. Clinicians should be aware of these clinical features of pemphigus for a more precise diagnosis and better management.

건선에 대한 Vitamin A acid 의 임상적 (臨床的) 및 병리조직학적 (丙利組織學的) 관찰

유태연 대한피부과학회 1971 大韓皮膚科學會誌 Vol.9 No.3

The 10 cases of psoriasis were treated with topical application of 0.3% of Vitamin A acid ointment, once daily, without dressing, and were observed at weekly intervals. Histopathological studies were obtained 5 cases out of former 10 psoriasis patients, before and 3 weeks after treatment. Clinical results(table 1)revealed 6 cases of good result, 4 cases of moderate resuIt in efficacy. In generally, the scales and infiltration were more rapidly responded to the treatment than the erythemas. Histopathological findings after treatment (table 2) were revealed, compare with before treatment, reduced or absence of parakeratosis, regenration of granular cell layer, reduced acanthosis, and decreased inflammatory cell infiltration in the upper derms. Side reaetions, as irritation dermatitis, occurred only on the normaI skin especially periollicular regions, which was cured easily by wet dressing with Burow's solution for a few days. Recurrences were occurred in 3 cases of the treated 10 patients, within 10 days after stop of the therapy.

5 Fluoro-Uracil로 치료한 첨규습우 4예에 대한 고찰

유태연 한일병원 1970 한일병원 임상잡지 Vol.1 No.1

淋巴腫 및 白血病의 皮膚症狀

兪泰演 대한의학협회 1972 대한의학협회지 Vol.15 No.2

알러지습진양 피부염의 치료

유태연 대한의학협회 1972 대한의학협회지 Vol.15 No.10

혼합종 1 예

김수남,유태연,허충림 대한피부과학회 1977 大韓皮膚科學會誌 Vol.15 No.3

Mixed tumor can be defined as arising from the skin, often from sweat glands, and as being composed of epithelial elements intermingled with cartilage or myxoid tissue in such a way that epithelial cells appear to be continuous with these otber types of cells without separation by a basement membrane. RecentIy, we had opportunity to observe a patient, 34-year-old woman, who had typical mixed tumor of the skin in the central portion of the chin. The tumor developed as a solitary, firm, rice-sized subcutaneous nodule which had been present for 6 months with little increase in size and without any pain and tendemess. The covering skin was normal except mild erythema. Clinically, the lesion was simiIar to sebaceaus cyst, Under local anesthesia, tbe whole tumor mass was removed surgically for histologic study. The histopathologic finding reveals nests of cuboidal or polygonal cells, tubuloalveolar and ductal structures, and homogeneous, faintly bluish chondroid or foamy a,ppearing matrix. (Photo. 1, 2, 3 & 4)

안면속립파종낭창(顔面粟粒播種狼瘡)의 1예

김난희,유태연 대한피부과학회 1972 大韓皮膚科學會誌 Vol.10 No.3

A case of lupus miliaris desseminatus faciei, 23 year old male was reported. The multiple minute discrete yellowish brown superficial nodules, 2 to 3 mm in diameter, revealed apple-jelly color under diascopy without any subjective symptoms since June, 1971. The lesions affect lower eyelids, forehead, cheeks, malar region, upper lip, chin and nasolabial folds symmetrically. Histopathological findings revealed conglomerated individual tubercles with prominent central caseation necrosis. He was given 600mg of INH and 12 mg of PAS daily per os for 2 months. The eruptions were healed gradually with pitted scars.

Jadassohn - Pellizali 형 원발성 반상피부위축증 (斑狀皮膚萎縮症 ) 1 예

김수남,유태연,허충림,박신애 대한피부과학회 1977 大韓皮膚科學會誌 Vol.15 No.3

Anetoderma or macular atrophies is a localized laxity of the skin, resulting from defect in the elastie tissue of the dermis. This defect produces a clinical picture consisting of circumscribed area of soft, thin and wrinkled skin, which can be pushed easily into the subcutaneous tissue by the examining finger. When the lesions appear without any preceding recognizable disorder, they considered to be primary macular atrophies. In this group, based on whether an inflammatory reaction has occurred before the appearance of macular atrophy, two types aer generally acknowledged: Anetoderma of Jadassohn-Pellizali has a preceding inflammatory reaction, whereas anetoderma of Schweninger-Buzzi has had no preceding discemible inflammatory changes. The authors observed a case of anetoderma of Jadassohn-Pellizali in a 34 year old male when showed bean to coin sized rovnd or oval, thin, soft and wrinkled macules on the trunk, shoulder and upper extremities. About 3 years ago, erythematous macules developed which extended for several months to reach a size of l.5 to 2.5 cm. Slowly each lesion faded from the cener to outward Ieaving soft and wrinkled macules(Fig.l). Routine physical and laboratory findings were within-normal-limit. Histopathological findings showed scanty and fragmentation of the elastic fiber of the dermis and perivascular non-specific inflammatory cell infiltration. (Fig. 2, 3 & 4) Diagnosis was confirmed by clinical and histopathological findings. Literature was briefly reviewed for the discussion.