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위민우 외 중앙대학교 의과대학 의학연구소 2006 中央醫大誌 Vol.31 No.1·2·3
Salivary duct carcinoma is a rare primary tumor of the salivary glands arising most frequently in the parotid gland. It has a male preponderance and occurs most often in patient over the age of 50 years. Its distinctive histological features include dilated ducts containing cells arranged in cribriform, papillary of solid patterns often with central necrosis and reminiscent of intraductal carcinoma of the breast. These features are associated with an obvious invasive component. It is an aggressive neoplasm and may metastasize widely, causing death in a high proportion of cases. We experienced one rare case of salivary duct carcinoma in submandibular gland which has been treated with submandibular gland wide excision and functional neck dissection and postopeartive concurrent chemo- therapy and radiation therapy. We report a salivary duct carcinoma in submandibular gland with a review of literature.