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      • 뇌허혈시 시간에 따른 상시상동 정맥혈 산소포화도와 뇌피질 체성감각 유발전위에 관한 연구

        우영철,장성호 고려대학교 의과대학 1996 고려대 의대 잡지 Vol.33 No.2

        Measuring jugular bulb venous oxygen saturation (SjvO_(2) for cerebral oxygen balance is reported to be a effective monitoring. But it is questioned that reduction in SjvO_(2), can explain or predict brain injury. In this study, the author evaluated superior sagittal sinus oxygen saturation and the cortical somatosensory evoked potential(SSEP) in 21 cats with induced brain ischemia. The cats were randomly divided into 3 groups in group Ⅰ (n=7), brain ischemia was induced for 5 minutes, in group Ⅱ (n=7) for 15 minutes and in group Ⅲ (n=7) for 30 minutes. Ischemia was induced by the intrathoracic occlusion of the innominate, the left subclavian and both mammarian arteries, and additionally the mean arterial blood pressure was maintained around 60 mmHg. Arterial blood pressure, heart rate, central venous pressure, arterial blood gases and superior sagittal sinus blood gases were evaluated before, during ischemia and 90 minutes after reperfusion. Cortical SSEP was recorded also before ischemia and 90 minutes after reperfusion. The results were as follows : 1. Six of 7 cats in group Ⅰ , four of 7 cats in group Ⅱ and none in group Ⅲ showed return of SSEP after 90 minutes of reperfusion. The amplitude was 43.1±7.7% and 15.7±5.9% of preischemia level in group Ⅰ and Ⅱ, respectively and there was significant difference between two groups (p<0.05). 2. During ischemia, superior sagittal sinus PCO, was abruptly increased to 102.5±31.6, 121.8±26.4, 116.6±48.5 mmHg in group Ⅰ , Ⅱ and Ⅲ respectively(p(0.05). pH was decreased to 6.99±0.13, 6.8320.09, 6.83±0.14 in group Ⅰ, Ⅱ and Ⅲ respectively (p<0.05). 3. During ischemia, superior sagittal sinus oxygen saturation was decreased to 42. I±11.1, 21.8±12.5, 26.5±9.2 % in group Ⅰ, Ⅱ and Ⅲ respectively (p<0.05) and there was significant difference between group Ⅱ and group Ⅱ (p<0.05). The above results suggest that measuring the superior sagittal sinus oxygen saturation can be a useful monitoring method for prediction of neural injury in cats with brain ischemia. But further study for cerebral venous blood sampling is needed.

      • SCOPUSKCI등재

        흉강경 수술시 이산화탄소 주입이 경정맥구혈 산소포화도에 미치는 영향

        우영철,손동섭 대한마취과학회 1997 Korean Journal of Anesthesiology Vol.33 No.2

        Backgrounds : Carbon Dioxide(CO2) insufflation during thoracoscopy may result in adverse hemodynamic consequences such as increase in central venous pressure, decrease in cardiac output and increase in arterial carbon dioxide pressure. But the cerebral effects of CO2 insufflation during thoracoscopy are not known yet. To evaluate the cerebral effect of CO2 insufflation during thoracoscopy, jugular bulb venous blood oxygen saturation and pressure were measured. Methods : Nine patients were underwent thoracic surgery by thoracoscopy and one lung ventilation. After operation, CO2 was insufflated and hemodynamic parameters, arterial blood pressure, heart rate, central venous pressure, jugular bulb pressure, arterial blood gases and jugular bulb venous blood gases were measured at intrathoracic pressure 5 mmHg, 10 mmHg and 15 mmHg respectively. Results : Central venous pressure was increased with insufflation of CO2 of 10 mmHg and 15 mmHg. Jugular bulb pressure was increased with insufflationof of CO2 of 5mmHg, 10 mmHg and 15 mmHg. Arterial PCO2, jugular bulb venous PO2 and jugular bulb venous blood oxygen saturation were increased with insufflation of CO2 of 5 mmHg, 10 mmHg and 15 mmHg. Conclusion : CO2 insufflation pressure of 5 mmHg or greater resulted in significant increase in jugular bulb venous blood oxygen saturation and pressure. (Korean J Anesthesiol 1997; 33: 330∼335)

      • 기관내 삽관 후에 발생한 편측 성대마비 1례 보고

        우영철 중앙대학교 의과대학 의과학연구소 2000 中央醫大誌 Vol.25 No.1

        Right vocal cord paralysis was developed in a previously healthy 22-yr-old patient who had undergone surgery for thoracic spine schwanoma unrelated to the course of the vagus nerve or recurrent laryngeal nerve, under the endothracheal anesthesia. After induction of anesthesia with thiopental sodium and pancuronium, the thachea easily intubated with a 8.0mm cuffed armored endotracheal tube and stylet. Surgery for tumor removal and poserior fusion lasted for 10 hours was unventful expect sinus tachycardia. On the 1st postoperative day, the patient complained hoarseness and on the 7th postoperative day, indirect laryngoscopic examination showed right vocal cord paralysis. Vocal cord paralysis healed completely within 40 days after operation. In the case, compression of the recurrent nerve by the high0positioned balloon of the tracheal tube was presumed as most possible cause.

      • SCOPUSKCI등재

        고혈압 환자에서 Fentanyl과 Esmolol의 병용 투여가 기관내 삽관에 의한 심혈관계 변동에 미치는 영향

        우영철 대한마취과학회 1999 Korean Journal of Anesthesiology Vol.37 No.6

        Background : To prevent hypertension and tachycardia after endotracheal intubation, esmolol and low-dose fentanyl have been used and it was reported that the combination of them was more effective than either in normotensive patients. However there have been few studies in this regard using hypertensive patients. Therefore, the author evaluated the effects of a combination of esmolol and low-dose fentanyl on hemodynamic responses after laryngoscopy and endotracheal intubation in hypertensive patients. Methods : Thirty hypertensive patients were premedicated with midazolam and glycopyrrolate. Fentanyl 2 μg/kg and esmolol 1 mg/kg were injected before induction of anesthesia. Thiopental sodium 3 5 mg/kg and succinylcholine 1 mg/kg were used for the induction of anesthesia. Endotracheal intubation was performed at 5 minutes after fentanyl injection. Thereafter 50% nitrous oxide in oxygen and 2 vol% enflurane were inhaled. Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood presure (MAP) and heart rate (HR) were measured before fentanyl injection (base), before intubation, and at 1, 3 and 5 minutes after intubation. Results : At 1 minute after intubation, SBP and MAP did not change significantly, but DBP increased slightly compared to base (P < 0.05). SBP, DBP and MAP decreased at 3 and 5 minutes after intubation (P < 0.05). HR did not change significantly. Hypertension (SBP>170 mmHg) developed in 2 patients at 1 minute after intubation, and hypotension (SBP<90 mmHg) in 3 patients at 5 minutes after intubation. Tachycardia (HR > 100 bpm) developed in 2 patents at 1 minute after intubation and bradycardia (HR< 50 bpm) in 1 patient at 5 minutes after intubation. Conclusions : In treated hypertensive patients, the use of a combination of fentanyl 2 μg/kg and esmolol 1 mg/kg is a useful method to attenuate hypertension and tachycardia after endotracheal intubation. (Korean J Anesthesiol 1999; 37: 995∼1000)

      • SCOPUSKCI등재

        복강경 수술시 이산화탄소 주입과 Trendelenburg-lithotomy 체위가 안압에 미치는 영향

        우영철,구길회,이보령 대한마취과학회 1997 Korean Journal of Anesthesiology Vol.33 No.3

        Background : The laparoscopy requires carbon dioxide(CO2) insufflation and Trendelenburg position for operational convenience. However, the above circumstances affect the cardiopulmonary systems significantly and intraocular pressure(IOP) may be also influenced. Methods : In 27 non-glaucoma patients right and left intraocular pressure(RIOP, LIOP) were measured 5 minutes after induction of general anesthesia(control value), 15 and 30 minutes after CO2 insufflation and endelenburg-lithotomy position. Results : The control values of RIOP and LIOP were 11.3 4.7 mmHg and 11.5 4.7 mmHg respectively. At 15 minutes after CO2 insufflation and Trendelenburg-lithotomy position, they increased to 16.6 5.3 mmHg and 17.0 5.9 mmHg(p<0.05). At 30 minutes, 18.4 3.5 mmHg and 18.2 4.1 mmHg(p<0.05). Conclusion : CO2 insufflation and Trendelenburg-lithotomy position increase IOP significantly in non-glaucoma patients during laparoscopy. (Korean J Anesthesiol 1997; 33: 529∼532)

      • KCI등재
      • SCOPUSKCI등재
      • SCOPUSKCI등재

        양측 교대형 안면신경 마비의 치험

        우영철(Young Cheol Woo),구길회(Gill Hoi Koo) 대한통증학회 1998 The Korean Journal of Pain Vol.11 No.2

        Facial nerve paralysis is a common pain clinical diagnosis. But ipsilateral or contralateral recurrent facial paralysis is found in about 2.6-19.5% of facial paralysis and especially bilateral facial paralysis is rare. While idiopathic facial paralysis is the most common diagnosis, a comprehensive evaluation must be completed prior to this diagnosis in patients with bilateral facial paralysis. A representative case of bilateral alternating facial paralysis treated with stellate ganglion block (SGB) is presented. A 57 years old male patient who had the onset of a right facial paralysis 7 months ago visited pain clinic. Five months after the onset of right facial paralysis, as it was improving, he developed a left facial paralysis. He had history of hypertension, diabetus mellitus and pain episode on mastoid process before facial paralysis developed. Electrical test showed incomplete neuropathy on both side and computed tomography (CT) scan was normal. He was treated with SGB, physical theraphy and aspirin medication. After 25 times SGB, he was recovered almost completely.

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