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정지은,우한영,우신재,Van Sang Le,최혜진 한국고분자학회 2014 Macromolecular Research Vol.22 No.5
Conjugated polyelectrolytes (CPEs) have been studied extensively as the optical platform for chemo- andbiosensor applications with high sensitivity by virtue of their light harvesting effect. A range of fluorescent CPEsbasedsensing schemes have been developed by utilizing fluorescence quenching via photo-induced electron transferand fluorescence resonance energy transfer, etc. Highly sensitive and selective detection assays can be realized bycombining the tunable optical properties of synthetic CPEs with specific binding characteristics of biomolecules(such as aptamer, antibody, protein, etc.). This article reviews the range of fluorescence-based optical assays with theCPEs-biomolecule complex as a signaling platform with in situ detection, remarkable sensitivity and selectivity, etc.