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윤대환 ( Dae Hwan Youn ),왕국환 ( Kun Hwan Wang ),한정희 ( Jeong Hee Han ),박현정 ( Hyun Jeong Park ),나창수 ( Chang Su Na ) 대한경락경혈학회 2005 Korean Journal of Acupuncture Vol.22 No.1
Objectives: Acupuncture has been used as treatment of disease in the korean medicine. In this study, it was investigated that effects of reduction of acupuncture techniques of five evolutive phase for appling excess in the heart, kidney on cardiovascular system as blood pressure and renin and atrial natriuretic peptide (ANP) in plasma, cardiac hypertrophy. Materials and methods: The experiments were performed on Sprague Dawley rats, 2K1C hypertension model was prepared by constricting the left renal artery with a sliver clip. Animals were then divided into seven groups, 2K1C induced and no treated group (Control), acupuncture on SP3·HT7(AC-1), LR1·KI1(AC-2), SP3·HT7·LR1·KI1(AC-3). The treatments were performed once a day for 10 days in rats. Results: The results are that the blood pressure was significantly decreased at 15days in AC-1 group. The cardiac hypertrophy was significantly decrease in AC-3 group. The activity of plasma ANP was increased in all groups without AC-1 group and the that of plasma Rein was decrease in AC-1, AC-2 groups than control group. Conclusions: These results suggest that acupuncture at SP3·HT7 and SP3·HT7·LR1·KI1 can be used as a therapy for controlling renal hypertension induced by 2K1C in the rats.