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이우택(Wootaek Lee),오지우(Jiwoo Oh),송석현(Sukhyun Song),남아현(Ahhyun Nam),신현정(Jennifer H. Shin) 대한기계학회 2009 대한기계학회 춘추학술대회 Vol.2009 No.11
Cell physiology is regulated extensively by biochemical factors. However, recent studies have identified many types of mechanosensitive cells to address the importance of mechanical cues in cell functions and motility. While extensive work exists on the effect of adhesive proteins on cells motility, little is known about how motility of cells is affected by the mechanical properties of their physical environment. The effects of substrate stiffness on the morphology and motility speed of 3 different cells have been investigated. Human dermal fibroblast, human keratinocyte HaCaT cell and human aortic endothelial cell (HAEC) were plated onto PDMS of varying stiffness, ranging from 10 ㎪ to 1.5 ㎫, and coated with the fibronectin. Our results show that there is an optimal migration stiffness range of each cell type. The modulation of mechanical cues such as altering the rigidity of cell environment may be the key mechanism used to regulate cell migration and wound healing.
PEMFC용 디젤 개질 시스템에서의 일산화탄소 제거 공정 모델링
배민석(Minseok Bae),오지우(Jiwoo Oh),김동연(Dongyeon Kim),배중면(Joongmyeon Bae) 대한기계학회 2015 대한기계학회 춘추학술대회 Vol.2015 No.11
Modeling of diesel reformer system for polymer electrolyte membrane fuel cell (PEMFC) was conducted with Aspen Plus software. In order to meet the carbon monoxide (CO) level requirement of PEMFC, water-gas-shift (WGS) and preferential oxidation (PROX) reactors were introduced with the auto-thermal reforming (ATR) reactor. WGS and PROX reactors were simulated with equilibrium reactor blocks to model each chemical reaction. Various operating conditions for WGS and PROX reactors were used to control the CO amount. Especially, temperatures of each reactor and the amount of additional oxygen for PROX reactor is modified. n-dodecane and 1-methylnaphtalene were used as synthetic diesel fuel. In result, proper operating condition to meet CO level requirement for PEMFC can be obtained.