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Piperazine Citrate 및 Bephenium Hydroxynaphthoate의 腸內 寄生蟲에 對한 集團驅蟲 效科
余鉉泰,朴相宰,梁龍石 中央醫學社 1973 中央醫學 Vol.24 No.2
This trial was carried out in order to find out the convenient method of anthelmintics administration for mass control of intestinal helminths. The drugs used for the study were piperazine citrate tablet (processed in Korea), piperazine citrate syrup (U.S.P) and bephenium hydroxynaphthoate (purchased from the United Kingdom) and each drugs were administrated in different doses and ways to each different study objective and the following results were obtained; 1. The ascaris egg negative conversion rate in the group used 70mg/kg piperazine citrate tablet, two times with one week interval was 77.3 per cent. 2. The ascaris egg negative conversion rate in the: group used a single dose of 4.40g was 86.6 per cent and that of the group used dose of 3.85g, two time in succeeding day (a total dose of 7. 70g) was 74. 1 per cent and that of the group used dose of 3.85g, three times in succeeding days (a total dose of 11.55g) was 82.3 per cent. 3. The efficacy of bephenium hydroxynaphthoate (Aicopar) against hook-worm, ascaris, trichocephalus and trichostrongylus was 93.6 per cent, 73.3 per cent, 32.6 per cent and 72.2 per cent and 72.2 per cent in egg negative conversion rate and also 98. 9 per cent, 87. 6 percent, 67. 0 per cent and 87. 5 per cent in E. P. G. reduction rate.