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모상현(Sang-Hyun Moh),이정훈(Jeong-Hun Lee),김형식(Hyoung-Shik Kim),여진희(Jin-Hui Yeo) 한국화장품미용학회 2015 한국화장품미용학회지 Vol.5 No.3
As natural plant-based industry has been expanded, the use of oriental medicinal plants as cosmeceutical material was received a lot of attentions in the cosmetic industry. Among various medicinal plants, Potentilla chinensis have been interested in its biological effects. Although several attempts were tried to study its biological effect as medicinal plant, only limited studies tried to evaluate its biological effect as cosmeceutical material. In this study, we examined the possibility of Potentilla chinensis extract as a cosmeceutical material. After extraction of Potentilla chinensis, biological evaluation including anti-inflammation, anti-wrinkle, whitening effect and moisturizing effect was performed as cosmeceutical material. As a result, the Potentilla chinensis extract showed remarkable biological activities through stimulating elastin and aquaporin-3, and inhibiting melanin synthesis, cyclooxygenase-2 expression and expression of metallopeptidase-1, respectively. These results show the potential use of Potentilla chinensis as a functional cosmetic material for anti-inflammatory, wrinkle improvement, skin hydration and whitening effects.
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권희연,최선일,조봉연,최승현,심완섭,한웅호,장길웅,최예은,여진희,조주현,이옥환,Kwon, Hee-Yeon,Choi, Sun-Il,Cho, Bong-Yeon,Choi, Seung-Hyun,Sim, Wan-Sup,Han, Xionggao,Jang, Gill-Woong,Choi, Ye-Eun,Yeo, Jin-Hui,Cho, Ju-Hyun,Lee, Ok-Hwan 한국식품영양학회 2019 韓國食品營養學會誌 Vol.32 No.5
The purpose of this study was to demonstrate the quality characteristics of Brassica juncea cultivated in Jeongseon (BJJ), South Korea. We analyzed the nutritional components and antioxidant activity of BJJ. As a result of the free sugar analysis, the contents of glucose and fructose in BJJ were $0.29{\pm}0.02g/100g$ and $0.10{\pm}0.00g/100g$, respectively. The major fatty acids were palmitic acid, octadecenoic acid and stearic acid. The palmitic acid was the highest at 31.22% of all fatty acids. The major minerals were identified as Ca, P, K, Mg and Na. The contents of vitamin $B_1$, vitamin $B_2$, vitamin $B_6$, vitamin C and vitamin E in BJJ were $0.02{\pm}0.00mg/100g$, $0.087{\pm}0.01mg/100g$, $0.02{\pm}0.00mg/100g$, $0.56{\pm}0.06mg/100g$ and $0.20{\pm}0.03mg\;{\alpha}-TE/100g$, respectively. As a result of the free amino acid analysis, total amino acid contents in BJJ were $2,801.21{\pm}115.38mg/100g$. L-proline content was the highest ($744.30{\pm}119.06mg/100g$) in BJJ. BJJ extract inhibits reactive oxygen species production in 3T3-L1 adipocytes. Also, BJJ extract exhibits a protective effect on oxidative stress in $H_2O_2$-induced human dermal fibroblast. These results indicate that BJJ comprises various valuable nutrients which can be used as functional food ingredients.
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송미영(Mi Young Song),정해수(Hae Soo Jung),김형식(Hyoung Sik Kim),이정훈(Jeong Hun Lee),여진희(Jin hui Yeo),박기원(Gi won Park),전찬우(Chanu Jeon),모상현(Sang Hyun Moh) 한국산학기술학회 2015 한국산학기술학회 학술대회 Vol.2015 No.1
최근 자연친화적인 천연식물을 활용한 산업이 증가하면서 화장품 시장도 자연친화적 약용식물을 사용한 한방화장품이 큰 영향력을 보이고 있다. 이에 본 연구는 국내 고랭지 자생 약용식물 중 딱지꽃를 택하여 화장품 소재로서의 가능성을 시험하였다. 딱지꽃은 항염 및 지혈, 진정제의 효능을 갖는 식물로 국내에 넓은 지역에 분포하여 원재료의 수급이 용이한 장점을 가진다. 이러한 딱지나무를 부위별로 추출하여 유효성분을 HPLC로 비교분석하였고, 각각 부위별 추출물의 효능을 피부세포를 이용하여 시험하였다. 그 결과 잎 추출물의 경우 COX-2의 발현을 저해하고, 줄기 추출물의 경우 collagen 분해를 억제 및 elastin의 발현을 증가시켜 주름개선에 효과적이며, 뿌리 추출물은 collagen 유지 및 elastin의 발현 증가를 통해 주름개선에 효과적임을 확인하였다. 이러한 결과는 딱지꽃 추출물의 항염, 주름개선 효능을 가진 기능성 소재로서의 활용 가능성을 보여준다.
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딱지꽃(Potentilla chinensis) 뿌리 추출물의 주요성분 분리동정
정해수 ( Hae Soo Jung ),김형식 ( Hyoung Shik Kim ),이정훈 ( Jeong Hun Lee ),모서진 ( Seo Jin Moh ),여진희 ( Jin Hui Yeo ),박기원 ( Gi Won Park ),모상현 ( Sang Hyun Moh ) 한국응용생명화학회 2016 Journal of Applied Biological Chemistry (J. Appl. Vol.59 No.1
딱지꽃(Potentilla chinensis)은 약초식물의 하나로 항염, 지혈, 해독 그리고 해열 등의 효과가 알려져 있다. 특히 딱지꽃의 뿌리는 약제로써 중요한 가치를 지니고 있다. 그러나 기존에 딱지꽃의 줄기나 잎에 대한 유효성분에 대한 연구가 시도된 반면 딱지꽃의 뿌리의 주요성분을 분석한 사례가 없었다. 따라서 본 연구는 딱지꽃의 뿌리를 다양한 용매별로 추출하고 주요한 물질을 분리정제 하였다. 분리 정제된 물질을 NMR과 mass 분석을 통하여 물질을 동정하였고 그 결과 주요성분이 화합물 (1)임을 확인하였다. 또한, 동정된 물질의 산업적 응용을 위해 딱지꽃 뿌리에서 용매별로 화합물 (1) 추출양을 정량하였다. One of oriental medicinal plants, Potentilla chinensis, has been used for anti-inflammation, hemostatic, decryption, and antipyretic. Especially, a root of Potentilla chinensis was used as important material for oriental medication. Although several kinds of bioactive component of Potentilla chinensis extract from stems and leaves were identified, the major component of Potentilla chinensis from roots is not well established. In this study, the root of Potentilla chinensis was extracted in different solvent system and analyzed by high performance liquid chromatography (HPLC). According to HPLC analysis, a major component was isolated and its physic℃hemical properties were evaluated by mass spectrometry and nuclear magnetic resonance. Based on these results, isolated compound was identified as 2,3,8-Tri-O-methylellagic acid. And quantification of 2,3,8-Tri-O-methylellagic acid with different extraction solvent system was performed for industrial application.
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