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RISS 인기검색어
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- 저자 : 어수택(Soo Teak Uh) (검색결과 1 건)
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천식 환자에서 고해상 흉부 단층 촬영을 이용한 폐기종의 평가
김용훈(Yong Hoon Kim),류은상(Eun Sang Ryoo),홍기영(Ki Young Hong),이준혁(June Hyuk Lee),이태영(Tae Young Lee),서문정(Moon Jung Seo),주재학(Jae Hak Joo),김도진(Do Jin Kim),문승혁(Sung Heuk Moon),어수택(Soo Teak Uh),박춘식(Choon Sik Pa 대한내과학회 2001 대한내과학회지 Vol.60 No.5
N/A Background : Bronchial asthma is a clinical syndrome characterized by reversiblity of airway obstruction. however, many asthma patients have evidence of residual airway obstruction. It has become evident that the repair of chronic inflammatory process can lead to various irreversible changes. It is generally accepted that the most common cause for change is cigarette smoking but it is controversial whether asthma progresses to emphysema. High resolution computed tomography (HRCT) is more sensitive and more accurate than chest plain films in determining the type and extent of emphysema. This study was carried out to determine whether asthma can be a cause of emphysema without the effect of cigarette smoking and to evaluate clinical characterics in asthma patients with emphysema. Methods : We studied 58 asthmatic patients with reversible airway obstruction and evaluated the presence of emphysema using HRCT and pulmonary function test. According to HRCT findings, they were divided into 2 groups: Asthma patients with and without emphysema. Results : Of the 58 patients, 7 were judged to have emphysema. (1) 6 asthma patients with emphysema were smokers, but one patient was nonsmoker. (2) Highly significant differences between patients with and without emphysema were found in cigarette smoking (p<0.01), smoking consumption (p<0.01). (3) There was no significant differences in the duration of asthma, age or sex between patients with and without emphysema. (4) There was no significant differences in FEV1 (%), FEV1/FVC (%), diffusing capacity for carbon monoxide (DLco) (%), DLco/alveolar volume between patients with and without emphysema (5) Differences between asthma patients without emphysema and those with emphysema were found to be significant in bronchial wall thickening (p<0.05) and in total Ig E (p=0.07). Conclusion : These results indicate that smoking is a main factor to cause emphysema in the patient with asthma.(Korean J Med 60:463-471, 2001)
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