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      • KCI등재

        식도 천공의 치료 및 임상적 분석

        심행선,김명구,김준수 대한이비인후과학회 2016 대한이비인후과학회지 두경부외과학 Vol.59 No.9

        Background and Objectives Esophageal perforation is relatively uncommon and requires careful diagnostic evaluation and expert management. It has a high mortality due to significant mediastinal and pleural contamination leading to sepsis and multiple organ failure. We reviewed our experience of esophageal perforation to determine how to better recognize such a lesion and facilitate its correct management. Subjects and Method A retrospective chart review was performed on all patients treated for esophageal perforation from January 2000 to March 2016. These patients have been studied with respect to gender and age distribution, causes, sites, clinical manifestation, complications, management and postoperative complications. Results Patients ranged in age from 21 to 87 years, with an average age of 57.6±12.4 years. Fifty of the patients were men and 21 were women. The causes of the perforations were as follows: foreign body retention (18 patients), trauma (17 patients), Boerhaave’s syndrome (22 patients), and iatrogenic (14 patients). The sites of esophageal perforation were: the cervical esophagus (25 patients), thoracic esophagus (44 patients) and abdominal esophagus (2 patients). Primary repair only was performed in seven (9.9%) patients, whereas 32 (45%) patients were treated with primary repair & patch, seven (9.9%) patients with T-tube drainage. Exclusion & division were performed in three (4.2%) patients and esophagectomy was performed in two (2.8%) patients. Twenty (28.2%) patients were treated conservatively. Conclusion Early recognition and appropriate management of esophageal perforation are essential for reduction of morbidity and mortality. Korean J Otorhinolaryngol-Head Neck Surg 2016;59(9):668-71

      • KCI등재

        Comparative Analysis of the Combined Therapeutic Effects of Lipoprostaglandin E1 on Sudden Idiopathic Sensorineural Hearing Loss

        심행선,김준수,김명구 대한청각학회 2017 Journal of Audiology & Otology Vol.21 No.1

        Background and Objectives: Viral and vascular disorders are considered to be a major cause of idiopathic sudden sensorineural hearing loss (ISSNHL). Lipoprostaglandin E1 (lipo- PGE1) has vasodilating activity and has been used to treat ISSNHL. The purpose of this study was to determine the specific therapeutic effects of lipo-PGE1 and compare them to other treatment modalities for ISSNHL. Subjects and Methods: The study group had 1,052 patients diagnosed with ISSNHL. All were treated with steroid, carbogen inhalation, stellate ganglion block (SGB), or PGE1. The CP group (steroid, carbogen inhalation, and PGE1 injection; 288 patients) was treated with lipo-PGE1 and carbogen inhalation, the CS group (steroid, carbogen inhalation, and stellate ganglion block; 232 patients) with steroid, carbogen inhalation, and SGB, the C group (steroid and carbogen inhalation; 284 patients) with steroid and carbogen, and the control group (steroid only; 248 patients) with steroid only. Patients in the groups receiving lipo-PGE1 received a continuous infusion of 10 μL lipo-PGE1. Results: The overall recovery rate after treatment was 52.2%, and recovery rates by group were 67.7% in the CP group, 54.3% in the CS group, 52.1% in the C group, and 32.2% in the control group. Therefore, the therapeutic results in groups treated with lipo-PGE1 were better than results in other groups. The difference was statistically significant. Conclusions: The study results suggested that the CP group received effective treatment modalities for ISSNHL. The combined therapy of lipo-PGE1 with carbogen inhalation in patients with ISSNHL was more beneficial than other treatment modalities.

      • KCI등재

        톱밥흡인의 제거와 마취관리

        심행선,이성호,박현식,신명근,강경우 대한마취통증의학회 2006 Korean Journal of Anesthesiology Vol.50 No.3

        The aspiration of a tracheobronchial foreign body can be a life-threatening incident. Early diagnosis and the bronchoscopic removal of the foreign bodies can protect a patient from serious morbidity and even mortality. We report an unusual case of a 28-year-old man who inhaled sawdust that required emergency airway management and bronchoscopic removal of the sawdust fragments. Anesthesia for a rigid bronchoscopy is a challenging procedure for an anesthesiologist who must share the airway with the bronchoscopist and maintain the adequate depth of anesthesia. Most of the sawdust fragments were extracted successfully using a rigid bronchoscope. The patient was discharged uneventfully within one week of hospitalization. (Korean J Anesthesiol 2006; 50: 327~31)

      • KCI등재후보

        체위 변화에 따른 복강경 수술의 혈역학적 변화의 비교

        심행선,신명근,성우성,김인규,이성호 대한마취통증의학회 2009 Anesthesia and pain medicine Vol.4 No.2

        Background: The authors evaluated the hemodynamic effects of body position measured by esophageal Doppler monitor (EDM) during laparoscopic cholecystectomy or gynecologic laparoscopic surgery. Methods: Fifty patients scheduled to undergo laparoscopic cholecystectomy (Group C) or gynecologic laparoscopic surgery (Group G), were divided into two groups. Pneumoperitoneum was instituted by CO2 gas and the intraperitoneal pressure was kept under 12 mmHg. Hemodynamic parameters at critical points were measured by the use of EDM: before skin incision (T1), 5, 10 and 15 min after changing position (T2, T3 and T4), and 5 min after CO2 exsufflation (T5). Results: MAP (mean arterial pressure) was significantly higher in Group G when compared with Group C 10 min after changing position (T3) (P < 0.05). CO (cardiac output) was significantly decreased in Group G when compared with Group C 10 min after changing position (T3) (P < 0.05). And there were not significant differences in HR (heart rate) between two groups. PV (peak velocity) was significantly decreased in Group G when compared with Group C 10 min after changing position (T3) (P < 0.05). And there were not significant differences in FTc (corrected flow time) between two groups. But FTc in Group C was restored after CO2 exsufflation, FTc in Group G was not restored after CO2 exsufflation. Conclusions: Changing position in the gynecologic laparoscopic surgery group can elevate MAP and decrease CO. Therefore, careful caution is required in patients with cardiovascular disease who are undergoing gynecologic laparoscopic surgery.

      • Hemodynamic Effects of Nicardipine Measured by Esophageal Doppler Monitor during Gynecologic Laparoscopic Surgery

        심행선 대한마취통증의학회 2008 Anesthesia and pain medicine Vol.3 No.1

        Background: The authors performed this study to investigate the hemodynamic effect of nicardipine using an esophageal Doppler monitor (EDM) during gynecologic laparoscopic surgery. Methods: Forty patients scheduled to undergo gynecologic laparoscopic surgery, were divided into two groups; the control group (Group C) and the nicardipine group (Group N). Pneumoperitoneum was initiated using CO2 gas and the intraperitoneal pressure was kept under 12 mmHg. Hemodynamic parameters at critical points were measured using EDM, i.e., before skin incision (T1), 5, 10 and 15 min after the initiation of pneumoperitoneum (T2, T3 and T4), and 5 min after deflation (T5). Results: Mean arterial pressure (MAP) was significantly lower in Group N patients than in Group C patients at 5 and 10 min after the initiation of pneumoperitoneum (T2 and T3) (P < 0.05). No significant heart rate (HR) differences were observed between the two study groups. Cardiac output (CO), peak velocity (PV) and corrected flow time (FTC) were significantly higher in Group N at 10 min after the initiation of pneumoperitoneum (T3) (all P < 0.05). Conclusions: The nicardipine continuous infusion at 0.5−2.0μg/ kg/min is effective at attenuating hemodynamic changes after pneumoperitoneum during gynecologic laparoscopic surgery.

      • KCI등재
      • SCOPUSKCI등재
      • SCOPUSKCI등재

        증례보고 : 진단되지 않은 계류 척수 증후군 환자의 척추마취와 관련된 후유증

        심행선 ( Haeng Seon Shim ),이성호 ( Seong Ho Lee ),박현식 ( Hyun Sik Park ),김인규 ( In Kyu Kim ),신명근 ( Myoung Keun Shin ),김재호 ( Jae Ho Kim ) 대한마취과학회 2007 Korean Journal of Anesthesiology Vol.53 No.1

        Tethered cord syndrome is a form of spinal dysraphism, with a low-lying conus frequently associated with an intraspinal lipoma, diastematomyelia or fibrous band. The clinical manifestations include spine abnormalities, such as spina bifida, or various neurological symptoms involving the lower extremities and sphincters. Herein, our experience of a 42-year-old female tethered cord syndrome patient, with deficit, paresthesia and incontinence following spinal anesthesia for anti-incontinence surgery, is reported with a brief review of literature. (Korean J Anesthesiol 2007; 53: 115~8)

      • KCI등재
      • Clinical Analysis of Acute Laryngotracheal Injuries

        심행선 ( Haeng Seon Shim ),김동준 ( Dong Joon Kim ),김정연 ( Jeong Yeon Kim ),김명구 ( Myung Gu Kim ) 중앙대학교 의학연구소 2018 中央醫大誌 Vol.43 No.1

        Background and Objectives: Recently, the incidence of laryngotracheal injuries has increased steadily with the increase in traffic collisions and mechanization. Acute laryngotracheal injury is relatively uncommon but has the potential for rapid progression and can become life-threatening. Early diagnosis and appropriate airway management are essential for avoiding significant morbidity and mortality. We investigated our cases with laryngotracheal injuries to present the clinical findings and evaluate their correct management. Subjects and Method: A retrospective chart review was done of all patients who had been treated for acute laryngotracheal injuries from January 2000 to March 2016. The patients were studied with attention to gender and age distribution, mode of injury, clinical signs and symptoms, injury mechanisms and causes, degree of injury, treatment and outcomes after the treatment. Results: Thirty-two patients with laryngotracheal injuries were included in the study. Twenty-six cases were categorized as blunt traumas, and the other six were penetrating traumas. Acute laryngotracheal injuries were more common in males, and odynophagia and voice changes were the most common symptoms. Seventeen patients were managed conservatively, and fifteen underwent surgery. Twenty-two patients recovered their normal voices, and ten were assessed as fair. All patients showed good airway outcomes after appropriate treatment. Conclusion: Immediate recognition of acute external laryngotracheal injury and expedient appropriate management are essential to good functional recovery from these potentially lethal injuries. Chung-Ang J Med 2018; 43(1): 1-5

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