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- 저자 : 신문섭 ( Moon Seub Shin ) (검색결과 5 건)
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입술에 발생한 염증성 병변에 대한 임상적 병리조직학적 분석
신문섭 ( Moon Seub Shin ),이운하 ( Un Ha Lee ),박현수 ( Hyun Su Park ),박혜진 ( Hai Jin Park ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.8
Background: Inflammatory labial lesions are quite common in dermatology. However, a few studies have been performed regarding the clinical and histopathological findings of inflammatory labial diseases. Objective: The purpose of this study was to investigate the clinical and histopathological features of inflammatory labial diseases. Methods: We retrospectively reviewed the data of 48 patients who underwent biopsy for inflammatory labial lesions between June 2005 and December 2012. Clinical features and histopathological findings of the lesions were investigated, and they were compared to each other for differential diagnosis. Results: The most frequent inflammatory labial diseases were actinic cheilitis (25%), oral lichen planus (23%), plasma cell cheilitis (23%), oral lichenoid lesion (17%), and eczema (12%). Most of the labial lesions were located on the lower lip (87%). We found a broad overlap in the clinical features of lesions with each other, and in many cases, clinical impressions were inconsistent with their final diagnosis. Histopathologically, the degree of eosinophilic infiltrates in actinic cheilitis was comparable to those in eczema. Oral lichen planus showed orthokeratotic hyperkeratosis rather than parakeratosis, and oral lichenoid lesion displayed more frequent perivascular and deep inflammatory cell infiltrates than oral lichen planus. Conclusion: The diagnosis of inflammatory labial diseases may be challenging, because inflammatory labial diseases often show similar clinical features and have a broad overlap in histological features. Therefore, clinico-pathologic correlation is necessary to confirm the diagnosis and for proper management. (Korean J Dermatol 2013;51(8):608∼ 615)
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녹색의 다환성 반을 보인 Churg-Strauss 증후군
신문섭 ( Moon Seub Shin ),김수진 ( Soo Jin Kim ),김성현 ( Seong Hyun Kim ),박혜진 ( Hai Jin Park ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.9
Churg-Strauss syndrome (CSS) or allergic granulomatous angiitis is a rare systemic vasculitis with tissue and blood eosinophilia. A 37-year-old woman with a 2-year history of allergic rhinitis and asthma presented with polycyclic patches on both extremities and trunk. Laboratory studies revealed peripheral blood eosinophilia, hyper-IgE, and positivity for ANA (1:40, speckled pattern). Skin biopsy specimens showed endothelial cell swelling, perivascular and interstitial eosinophilic infiltration with nuclear dust in the dermis. She was treated with methylprednisolone and showed an improvement in symptoms. Two years later she developed a tingling sensation on her right hand and right lower extremity along with aggravation of skin lesions. The skin examination revealed erythematous papules and greenish patches on buttock and finger joints. On the histological examination of the patches on the buttock, prominent extravascular eosinophilic infiltration, endothelial cell swelling and degenerative collagen fibers were observed in the dermis. (Korean J Dermatol 2011;49(9):812~817)
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서지영 ( Ji Young Seo ),신문섭 ( Moon Seub Shin ),김수진 ( Soo Jin Kim ),허식 ( Sik Haw ),김성현 ( Seong Hyun Kim ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.2
Papular xanthoma is a rare normolipemic xanthomatous skin disease that primarily occurs in adults. While this rare disorder has been documented in children before, all but one case reported in the literature involved a normal lipid profile. The skin lesions of adult papular xanthoma appear to be persistent, whereas in children they generally self-heal within 1∼5 years. Here, we describe a typical case of papular xanthoma in a 22-month-old boy who presented with numerous reddish-yellow papulonodules, 2∼8 mm in diameter, mainly on the face, but also on the upper and lower extremities, and trunk, for 15 months. The lipid profile was normal, and histological studies showed a diffuse monomorphous infiltrate of foamy cells, with some Touton giant cells, in the dermis. The foamy cells stained positive for Cluster of Differentiation (CD) 68, and the Periodic Acid Schiff (PAS) stain was negative. These findings are consistent with the diagnosis of papular xanthoma.
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김수진 ( Soo Jin Kim ),신문섭 ( Moon Seub Shin ),박혜진 ( Hai Jin Park ),김성현 ( Seong Hyun Kim ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.11
Disseminated superficial porokeratosis (DSP) is a keratinization disorder characterized by multiple small lesions with a slightly elevated, sharply defined ridge over the whole body. Inflammatory DSP has common clinical features, which involve a several-year history of asymptomatic DSP and the sudden appearance of intensively pruritic erythematous papules over the entire body. These lesions subside within several months, leaving a brownish atrophic lesion. We report on a 64-year-old man who displayed an atypical clinical feature of inflammatory DSP. (Korean J Dermatol 2011;49(11):1053∼1055)
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최용규,신문섭,이병걸 한국환경과학회 2000 한국환경과학회지 Vol.9 No.2
국립수산진흥원의 한국 연안 어장환경 오염조사 결과 보고서를 사용하여, 인천 연안역의 수온 및 염분의 계절변화의 특성을 살펴 보았다. 수온의 연변화는 인천항과 소래에 이르는 조간대 해역이 만의 바깥쪽 해역보다도 수온의 연평균이 높고, 진폭도 크며, 위상도 빨랐다. 염분의 연변화는 인천항과 소래에 이르는 조간대 해역이만의 바깥쪽 해역보다도 연평균은 낮고, 진폭은 크며, 위상은 느리게 나타났다. 이러한 특성은 T-S도를 이용하여 나타낸 수괴의 계절 변화에서도 뚜렷하게 볼 수 있었다. 즉, 인천 연안역의 수괴는 수온과 염분의 연교차가 큰 인천과 소래에 이르는 조간대 해역과 염분 변동에 영향을 주는 강수나 증발, 담수 유입의 계절적 변화에 비교적 영향을 적게 받는 만의 바깥쪽 해역으로 구분할 수 있었다. 또한 얕은 수심과 강한 조류로 인하여 수층이 연중 거의 혼합된 분포를 보이고 있었다. The seasonal data obtained at National Fisheries Research and Development Institute from 1989 to 1994 were analyzed to investigate the seasonal variations of temperature and salinity in Incheon coastal area. In the tidal flats covering from Incheon harbor to Sorae, the mean temperatures are higher, the amplitudes of temperatures are larger, and the phases of temperatures are faster than those of outer tidal flats. In the tidal flats, the mean salinities are lower, its amplitudes are larger, and its phases are later than those of outer tidal flats. These suggest that Incheon coastal area may be divided into two areas: the tidal flats from Incheon harbor to Sorae, which is largely influenced by the seasonal variation of solar heating, precipitation and evaporation and the outer tidal flats, which is slightly influenced by the effects of seasonal variation of salinity.
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