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홍순철(Soon Choul Hong),송준석(Jun Souk Song),조수훈(Soo Hun Cho),송재윤(Jae Yoon Song),박선영(Seon Young Park),김영태(Young Tae Kim),김선행(Sun Haeng Kim),이규완(Kyu Wan Lee) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.1
N/A Objective : To know when we can identify fetal Y chromosome SRY gene by using fetal DNA in maternal plasma. Methods : DNA from maternal plasma of 62 pregnant women (48: inpatients, 14: outpatients) underwent a sensitive Y-PCR assay to identify SRY gene of Y chromosome. Results : Of the patients, fetus-derived Y sequences were detected in 37 (88.1%) of the 42 maternal plasma samples from women bearing male fetuses. One of the 20 women bearing female fetuses had positive result from plasma DNA. Seventh gestational week was the earliest gestation of gender identification. Conclusion : We could identify fetal gender using fetal DNA in maternal plasma (sensitivity 88.1%). The earlist to detect was 7th gestational week.