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        전용선 해운업 발전 방안에 관한 연구

        손현호(Hyun-Ho Son),이재성(Jae-Sung Lee) 한국해양비즈니스학회 2011 해양비즈니스 Vol.- No.19

        The concept of dedicated shipping is building a new vessel by guaranteed cargo loading and carriers operate for a certain consignor until the end of durable years. Under this contracts, consignors promise boatful operation and a reasonable profit included prime coast. Shipping business is too dependent on manufacturing industry. When economy is in depression, only shipping business participants are able to do is just awaiting. Therefore, said industry need to develop growth engines by its own. Proposals for establishment of dedicated shipping business in this thesis are as in the following. First, carriers and shippers may organize consortiums to exploit resources in overseas. Second, competitiveness of shipping finance must be progressed. Third, through continuing tonnage dues system, restricting market entry of large scale consignors into shipping business and standardizing types of ships by joint extensive orders from carriers and shippers, unnecessary argument and cost should be eliminated and prime cost of carriage should be reduced.

      • SCOPUSKCI등재

        Hydroxychloroquine 투여로 호전을 보인 궤양성 지방생괴사

        손현호 ( Hyun Ho Son ),권태광 ( Tae Gwang Kwon ),심현수 ( Hyun Soo Sim ),이숙경 ( Sook Kyung Lee ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.11

        Necrobiosis lipoidica (NL) is a chronic granulomatous skin disease of unknown etiology, which can be seen in patients with diabetes mellitus. Typical lesions of NL appear on the pretibial skin as painful yellow-brown inflammatory plaques with raised borders and atrophic centers. Ulceration occurs in approximately 35% of cases, leading to increased risk of secondary bacterial infection and scarring. Although there have been many proposed therapies for ulcerative NL, the response to treatment is often met with limited success. Here, we report a case of a 19-year-old girl with ulcerative NL, which showed improvements with oral hydroxychloroquine, an antimalarial agent. (Korean J Dermatol 2012;50(11):994∼997)

      • SCOPUSKCI등재

        한국인에서 수장족저농포증과 흡연의 연관성에 대한 연구

        손현호 ( Hyun Ho Son ),이영석 ( Young Seok Lee ),이숙경 ( Sook Kyung Lee ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.11

        Background: Palmoplantar pustulosis (PPP), a skin disease, is characterized by chronically recurring sterile pustules on the palms and the soles. Although the etiology of PPP is unknown, it is interesting to note high prevalence of tobacco use in these patients. It would seem that there may be a relationship between PPP, autoimmune disease and alterations of thyroid function. However, this fact was never verified among Korean. Objective: This study aims to explore smoking as a risk or exacerbation factor for PPP in Korean patients with PPP, and confirm the relationship between PPP and other factors, including thyroid disease. Methods: We studied a total of 109 patients (M:F=38:71) with ages ranging from 20 to 70 years, diagnosed with PPP. A control group was matched according to gender and age: 109 patients with other dermatologic problem. Patients were interviewed about tobacco use, and thyroid disease, and autoimmune diseases. The data were analyzed to determine whether there was any association between PPP and various factors. Results: The proportion of PPP patients using tobacco was much higher than that of the control group (p<0.05). Smoking was more strongly associated with PPP among women. Although there was no association between the quantity of cigarettes smoked daily and the severity of PPP, there was a dose-dependent correlation between the pack*year and the severity of PPP (p<0.05). Furthermore, 14 patients had been diagnosed with thyroid disease. In addition, all of them were smokers. Conclusion: There was significant association between PPP and smoking. However, the impact of giving it up in the clinical course of the disease remains to be established. In addition, it would seem that there may be a relationship between PPP and alteration of thyroid function. (Korean J Dermatol 2012;50(11):945∼950)

      • SCOPUSKCI등재

        Bleomycin 병변내 주입 후 호전을 보인 다발성 모낭상피종

        손현호 ( Hyun Ho Son ),정세원 ( Se Won Jung ),심현수 ( Hyun Soo Shin ),이숙경 ( Sook Kyung Lee ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.9

        Multiple trichoepithelioma is a benign adnexal neoplasm characterized by the presence of many small papules that appear predominantly on the face, Clinical improvement have been demonstrated after several treatments such as carbon dioxide laser, cryotherapy, dermabrasion, and argon laser. However, these destructive methods have various disadvantages. We report a case of multiple trichoepithelioma treated with an intralesional bleomycin injection. Fewer lesions without scars and cosmetic improvements were observed. Bleomycin is a cytotoxic antitumor antibiotic that can be injected intralesionally by transcutaneous administration and displays excellent results for treating malignancies including skin tumors. We believe that intralesional bleomycin injection is an effective treatment option for this condition, and an easy method to conduct at the outpatient clinic.

      • SCOPUSKCI등재

        항합성효소 증후군의 양상을 보인 급성 간질성 폐렴이 동반된 피부근염

        손현호 ( Hyun Ho Son ),정세원 ( Se Won Jung ),심현수 ( Hyun Soo Sim ),이숙경 ( Sook Kyung Lee ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.8

        Dermatomyositis is a systemic inflammatory disease affecting the skin, skeletal muscle, and occasionally, other organs, such as the lung. Interstitial lung disease (ILD) is a serious lung complication, which can occur in patients with dermatomyositis. It affects the prognosis of the disease and requires a more aggressive therapeutic approach. Interstitial lung disease (ILD) may be associated with systemic inflammatory disorders and autoantibody production. In particular, anti Jo-1 antibody has long been recognized as an important predictive factor in systemic manifestations of ILD in dermatomyositis. We report here a case of a 42 year old woman with cutaneous lesions typical of dermatomyositis, showing clinical features of antisynthetase syndrome, which showed rapid progression to acute respiratory distress syndrome.

      • SCOPUSKCI등재

        동상으로 인한 골수염에서 발생한 편평세포암

        황보현 ( Hyun Hwangbo ),이택근 ( Taek Geun Lee ),정세원 ( Se Won Jung ),손현호 ( Hyun Ho Son ),이숙경 ( Sook Kyung Lee ) 대한피부과학회 2015 대한피부과학회지 Vol.53 No.7

        Squamous cell carcinoma commonly originates from recalcitrant wound sites, including burn scars, pressure sores, stasis ulcers, osteomyelitis, and sites of frostbite. A 62-year-old male was referred to the dermatology department for skin necrosis of his right great toe and walking difficulty. He had a history of smoking, drinking alcohol, and frostbite of his right great toe 9 years prior, which deteriorated into osteomyelitis due to poor care. Although a skin biopsy was recommended before amputation, the two procedures were performed simultaneously due to a lack of toe function due to severe osteolysis. Biopsy of the amputated toe tip showed many lobules consisting of atypical keratinocytes with hyperchromatic nuclei, and severe dermal pleomorphism. After evaluation for distant metastasis, including a (99m) Tc-MDP bone scan, 18F-FDG positron emission tomography scan, computed tomography, and ultrasound, no metastasis was detected. (Korean J Dermatol 2015;53(7):556∼559)

      • SCOPUSKCI등재

        성인의 대상포진에서 Famciclovir와 Valacyclovir의 치료 효과에 대한 비교 연구

        황보현 ( Hyun Hwang Bo ),정세원 ( Se Won Jung ),손현호 ( Hyun Ho Son ),이숙경 ( Sook Kyung Lee ) 대한피부과학회 2014 大韓皮膚科學會誌 Vol.52 No.10

        Background: Famciclovir and valacyclovir are antiviral agents commonly used to treat herpes zoster. These medications not only reduce the time to complete cessation of zoster-associated pain, but also aid in the healing of the herpes zoster skin lesions. However, only few studies have compared these antiviral agents. Objective: We conducted a randomized clinical trial to evaluate the extent of pain relief and wound healing, and the rate of postherpetic neuralgia associated with these drugs during 4 weeks of treatment. Methods: The study included 69 immunocompetent adult inpatients diagnosed with herpes zoster randomly divided into 2 groups based on the antiviral agent administered. Patient age, date of visit from rash onset, and rash severity at baseline were recorded. Famciclovir or valacyclovir were administered orally for 7 days. Patients reported pain levels through a visual analog scale (VAS) score, and pain durations were assessed on days 1, 3, and 7, and at weeks 2, 3, and 4. Crust formation and reepithelialization times of skin lesions were also recorded. Results: VAS scores, pain durations, ratios of patients undergoing postherpetic neuralgia, and skin lesion healing rates did not differ significantly between the 2 groups. However, rash severity independently correlated with the extent of pain experienced. Conclusion: Famciclovir and valacyclovir are comparable to each other in resolving zoster-associated pain, postherpetic neuralgia, and zoster wound healing. Early antiviral treatment before expansion of the skin lesion would be helpful for rapid relief of herpes zoster pain. (Korean J Dermatol 2014;52(10):720∼727)

      • SCOPUSKCI등재

        대상포진 환자에서 급성기 통증과 포진후 신경통 발생 억제 효과에 대한 Light Emitting Diode (LED)의 효과

        정세원 ( Se Won Jung ),손현호 ( Hyun Ho Son ),이영석 ( Young Seok Lee ),이숙경 ( Sook Kyung Lee ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.10

        Background: Acute pain and postherpetic neuralgia often interfere with life quality severely. Light emitting diode (LED) has been proposed as one of the effective therapeutic tools for pain reduction. However, little has been published in the Korean medical literature about the effect of LED on acute pain and the inhibitory effects of postherpetic neuralgia (PHN) in patients with herpes zoster. Objective: The purpose of this study was to evaluate the efficacy of LED on acute pain and the inhibitory effects of PHN in patients with herpes zoster. Methods: Sixty patients who were hospitalized for herpes zoster were evaluated according to their age, sex, associated disease, nature of pain, interval between diagnosis, therapy, and PHN. The patients were randomly placed into either a LED group treated with I.V acyclovir, analgesics and LED or a control group treated with I.V acyclovir and analgesics alone. The severity of pain was evaluated by patients themselves using a visual analogue scale (VAS) and a verbal rating scale (VRS) at one week intervals. The occurrence of PHN was assessed at 4 weeks after the initial development of the characteristic skin lesion of herpes zoster. Results: The average days required for pain relief was significantly shorter in the LED group than the control group. The average weeks needed to reduce pain from 100 to 50 in the VAS, implicating relief of acute pain, were 1.4 weeks in the LED group and 1.8 weeks in the control group (p<0.05). The total number of patients reported to have experienced a drop in the amount of pain from 100 to 50 within a week was greater in the LED group (20 patients) than the control group (10 patients) (p<0.05). However, there was no difference in the onset of PHN between the two groups (p>0.05). Conclusion: LED is an effective method which can be used to relieve acute herpes zoster pain quickly; however, LED cannot reduce the onset of PHN effectively. (Korean J Dermatol 2013;51(10):763∼770)

      • SCOPUSKCI등재

        외과적 절제술 후 IPL 제모술로 재발을 방지한 모소동

        서종원 ( Jong Won Seo ),손현호 ( Hyun Ho Son ),최준희 ( Joon Hee Choi ),이숙경 ( Sook Kyung Lee ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.11

        Pilonidal sinus (PS) is one of follicular occlusion tetrad, and this is a chronic inflammatory disease that`s characterized by a sinus or cyst with entrapped hair in the midline of the sacral region. The exact pathogenesis of PS remains unknown, but hair insertion may be the essential cause of the disease. PS is usually treated by surgical excision, marsupialization or incision and curettage. However, these surgical options often exhibit high recurrence rate, and especially for hirsute patients. Laser epilation has recently been recommended as an effective postoperative adjunctive therapy for PS and this treatment may reduce recurrence of PS. We report here on a 37-year-old male patient with PS, and the PS was treated by surgical excision and postoperative intense pulsed light (IPL) epilation. (Korean J Dermatol 2009;47(11):1288~1290)

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