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민간 산후조리원 공공성 제고를 위한 산후조리서비스 체계 고찰 및 개선 방안
김희선 ( Hee-Sun Kim ),이재희 ( Jae Hee Lee ),이정림 ( Jeong Rim Lee ),엄지원 ( Ji-Won Eom ),구자연 ( Ja Yeun Koo ),박병록 ( Byoung Lok Park ),박현수 ( Hyun Soo Park ),손인숙 ( In Sook Sohn ) 한국모자보건학회 2021 한국모자보건학회지 Vol.25 No.3
The study aimed to review the current postpartum care service system and suggest measures of improvement for the public reinforcement of the private-postpartum care center (PCC). We conducted a review of literature, including an internet search, and we analyzed the in-depth interviews using questionnaires answered by workers from the 6 private-PCCs operated in Goyang city. Using these data, we derived possible measures which could improve the publicity of private-PCCs. It was found that the 11 nationwide public-PCCs had serious operating deficits, and its utilization by the vulnerable was insufficient. In areas where private-PCCs are concentrated, we can propose the following policies to strengthen publicity, rather than establishing another public-PCC. First, it is important to provide support for private-PCCs to apply cost reductions for vulnerable groups, similar to the maternal and newborn medical care of public- PCCs. Second, publicity would be strengthened by reorganizing the pregnancy and childbirth education program, while also offering additional services for mothers with stillbirths and abortions. For the integrated management of postpartum care services, this should be shifted towards reinforcing the publicity of private-PCCs, rather than operating a public-PCC in relative ly concentrated private-PCC areas. Through these policies, it is expected that financial and administrative waste will be reduced, and an integrated management system for postpartum care services will be established.
박찬규(Tchan Kyu Park),이성기(Sung Ki Lee),손인숙(In Sook Sohn),김수녕(Soo Nyung Kim),김영문(Young Moon Kim),김호근(Ho Guen Kim) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.3
N/A Objective: Tumor angiogenesis is believed to conelate with tumor growth, progression and metastasis. Studies of angiogenesis in breast, prostate and melanoma have shown that angiogenesis, the induction of new capillaries and venules, is associated with tumor metastases and recurrences. The purpose of this study was to investigate the angiogenesis as a prognostic factor in invasive cervical cancer. Methods: Forty-three formalin fixed embedded blocks of invasive cervical cancers were examined using immunohistochemical staining with a monoclonal antibody against factor VIII-related antigen. Results: The miaovessel counts were 53.50+-20,07 in patients with lymph node metastasis, and 45.97+-28.12 in those without such metastasis. There was a trend for the microvessel count to increase with lymph node metastasis. However, thae was no significant difference in microvessel counts regarding node status. There was no significant difference between microvessel counts in patients with stage I(47.90+-25.89) and those with stage Il(45.50+-29.27), The microvessel counts in squamous cell carcinoma(46.54+-27.79) were not significantly different from those in adenocarcinoma(47,50+-27.05), The microvessel count in patients with tumor size >-4 cm(53.00+-21.17) was not significantly higher than in those with tum#ar size <4 cm(46.20+-27.94). Conclusion: There was no significant correlation between microvessel counts and clinical stage of disease, pathological type, tumor size or lymph node metastasis in patients with invasive cervical cancer. There was a trend for the microvessel count to increase with lymph node etastasis.
부인과종양에서 Tissue Polypeptide Antigen 측정에 관한 연구
유연웅(Yeon Wung You),김수녕(Soo Nyung Kim),손인숙(In Sook Sohn),이지영(Ji Young Lee) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.8
N/A Objective : The measurement of tumor-associated antigen as tumor makers in the serum is useful for early diagnosis, differential diagnosis, and the determination of remission after therapy in cases of malignancy. A tumor-associated antigen is not always present in all the cells forming the tumor and also be detected in other tumors or normal organs. Tissue polypeptide antigen (TPA) is a single polypeptide chain without carbohydrate. TPA has immunosuppresive properties in patients with cancer. The aim of this study was to evaluate the clinical usefulness of the cytokeratin tumor marker TPA in early diagnosis of patients with the gynecologic cancer. Methods : In this study, the levels of TPA were measured in the serum of 61 patients with benign gynecologic tumors, 24 patients with malignant gynecologic neoplasms, and 38 healthy nonpregnant females. Serum TPA level was measured by a “sandwitch technique based” radioimmunoassay. Results : As a result, serum TPA level was 30.4±7.6 U/L in control group, 32.6±9.4 U/L in benign gynecologic tumor group, 39.1±9.8 U/L in malignant gynecologic neoplasm. Serum TPA level was 56.6±7.0 U/L in ovarian cancer group. Conclusion : Serum levels of TPA was increased in the ovarian cancer group, but it does not seem to be a useful tumor maker for non-ovarian cancer. It would seem that measurement of TPA is useful for early diagnosis of ovarian cancer.
손인숙 ( In Sook Sohn ),유달영 ( Dal Yeong Yoo ),장동욱 ( Dong Wook Jang ),차윤정 ( Yun Jeong Cha ),김수녕 ( Soo Nyung Kim ),이지영 ( Ji Young Lee ),윤병일 ( Byung Il Yun ),정소정 ( So Chung Chung ),박기현 ( Ki Hyun Park ),이병석 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.8
목적: 조기난소부전은 난소발달기전을 이해하는 임상적 모델로, 조기난소부전의 유전적 원인을 밝힘으로써 난소분화 및 난포 형성과정에 관련된 유전자를 알 수 있다. 조기난소부전은 40세 이전에 무월경과 성선자극호르몬이 증가되는 임상증후군으로 빈도는 약 1% 정도이다. 아직 조기난소부전의 기전은 밝혀지지 않았고, 터너 증후군, 자가면역질환, 항암제 치료, 방사선 치료 및 감염 등이 원인으로 알려져 있다. 많은 유전자가 조기난소부전의 후보 유전자로 제기되었고, Objective: Premature ovarian failure (POF) is a highly heterogenous condition, and its etiology remains unknown in approximately two-thirds of cases. POF can be caused by Turner syndrome, genetic disease, iatrogenic agents such as chemotherapy and radioth
손인숙 ( In Sook Sohn ),김지연 ( Ji Yeon Kim ),권한성 ( Han Sung Kwon ),이선주 ( Sun Ju Lee ),이지영 ( Ji Young Lee ),김수녕 ( Soo Nyung Kim ),최원혁 ( Won Hyeok Choe ),우남식 ( Nam Sik Woo ),한혜승 ( Hye Seung Han ) 대한산부인과학회 2006 Obstetrics & Gynecology Science Vol.49 No.12
Acute fatty liver of pregnancy is a rare but usually fatal complication of the last trimester of pregnancy. The primary therapy is early delivery and supportive care. We report two cases of favorable outcomes in acute fatty liver of pregnancy. First case was a nulliparous twin pregnant woman at 33 weeks of gestation with jaundice, abdominal pain, and diarrhea. Because the acute fatty liver of pregnancy was diagnosed by typical laboratory findings, an emergency cesarean section was performed. Then, she showed the symptoms of acute renal failure, and the laboratory findings of disseminated intravascular coagulation. Second case was a nulliparous women at 37 weeks of gestation with malaise, upper abdominal pain, and elevated transaminase level. Under the impression of the acute fatty liver of pregnancy and fetal distress, an emergency cesarean section was performed under both epidural and general anesthesia. Liver biopsy was performed and showed microvesicular fatty infiltration of hepatocyte. In spite of the literature`s dismal prognosis, our cases seemed to be favorable maternal and perinatal outcomes because of early recognition and immediate termination of pregnancy with intensive and supportive care
손인숙 ( In Sook Sohn ),김수녕 ( Soo Nyung Kim ),이지영 ( Ji Young Lee ),이선주 ( Sun Joo Lee ),권한성 ( Han Sung Kwon ),김영진 ( Young Jin Kim ),우남식 ( Nam Sik Woo ),최영숙 ( Young Sook Choi ),이홍기 ( Hong Ghi Lee ) 대한산부인과학회 2006 Obstetrics & Gynecology Science Vol.49 No.11
Essential thrombocythemia (ET) is a chronic myeloproliferative disease characterized by a markedly elevated platelet count in the peripheral blood due to excessive proliferation of bone marrow megakaryocytes. When the disease affects women during pregnancy, an adverse obstetric outcome is possible: miscarriages, intrauterine growth restriction, preterm delivery, intrauterine fetal death, preeclampsia. Maternal complications, both thrombotic and hemorrhagic, were reported relatively infrequently. Various treatments as acetylsalicylic acid, hydroxyurea, anagrelide, heparin, interferon-alpha and plateletpheresis have been proposed to improve the pregnancy. Our case was a 38 years old multiparous women at 37 weeks of gestation with preeclampsia, intrauterine growth restriction. Under the impression of oligohydramnios and fetal distress, an emergency cesarean section was performed under epidural anesthesia. During cesarean section, sudden cardiac arrest with unknown cause was developed, and successful resuscitation was done. After cesarean section, patient continued to elevate platelet count. So bone marrow aspiration and biopsy were performed and showed essential thrombocythemia. We report a case of essential thrombocythemia diagnosed during pregnancy with brief review of the literature.