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      • 고양이 뇌 위둔덕에 출현하는 Neuropeptides 양성세포에 대한 면역조직화학적 연구

        손미아 翰林大學校 1992 국내석사

        RANK : 248639

        The distribution and morphology of cholecystokinin-8 (CCK 8)-, neuropeptide Y (NPY)-, substance P (SP)- and vasoactive intestinal polypeptide (VIP)-immunoreactivty were examined in the cat superior colliculus (SC) by means of immunohistochemistry. SP- and VIP-immunoreactive (IR) neurons and fibers were identified but CCK-8- and NPY-immunoreactivity was not detected. SP-IR perikarya were confined to the superficial layers with the highest density in intermediate layer of the stratum griseum superficiale (SGS). These neurons included seven cell types in shape: marginal, horizontal, angular, vertical fusiform, horizontal fusiform, stellate and granular cells. The majority of cell types were angular neurons and fusiform neurons. SP-IR fibers were seen in the SC and they formed extensive networks. The highest density of SP-IR fibers was noted in the dorsal half of the SGS. The direction of SP-IR fibers in the superficial layers was horizontal to the stratum zonale (SZ), and that in the other layers was irregular. VIP-IR perikarya were horizontal cells in type and located in the most superficial SGS. Density of VIP-IR fibers was moderate in the superfical SGS and low in the SZ, and absent in the other layers. These fibers were projected horizontally. Judging from this study, some neuropeptides-IR neurons may be present in the superficial layers of the SC. And these neurons and neuropeptides may be involved in the functions of the superficial layers.

      • Occupational class and health : the differentials in mortality, morbidity and workplace injury rates by occupation, education, income and working conditions in Korea

        손미아 London School of Hygiene and Tropical Medicine 2001 해외박사

        RANK : 248623

        Background: health differentials between socio-economic classes and increasing general inequalities in health have become worldwide concerns. However, little research has been carried-out concerning inequalities in health in developing countries. Objective: this thesis explores the relationship of occupation, education, income and working conditions to mortality, morbidity and workplace injury rates in Korea, focusing on the association of occupational class with health inequalities. Methods: the study uses existing Korean national data on occupation, socio-economic factors, mortality, morbidity and workplace injuries, along with a cohort for workplace injury analysis in a Korean car factory. SMRs, PMRs, Poisson regression, logistic regression, multilevel and Cox regression analyses are used to explore the relationship of occupation, education, income, health behaviours and working conditions with mortality, morbidity, and injury rates. In-depth interviews and walk-through surveys are undertaken in order to gain insight into working conditions, focusing on increases in work intensity in one car factory. Results: we show that occupational class is strongly related to mortality, morbidity, and deaths due to workplace injuries, for both male and female workers in Korea. We also conclude that there is an inverse relationship between education and mortality, as well as between education and income and morbidity and deaths due to workplace injury. After adjusting for education, the occupational effect on mortality and morbidity reduces. In the particular car factory used in the study, workers in the press and body welding departments, and those working at the conveyer line and doing shift work, suffer significantly higher injury rates. We note, in particular, an increasing incidence of lower-back pain, especially HIVD, from 1995 to 1997. In-depth interviews and walk-through surveys indicate that this was a period in which work intensity increased significantly. Discussion: This study has a data quality limitation, a numerator-denominator bias is possible, as variables from the secondary data were not collected specifically for this piece of research. Nevertheless, we suggest that education has an influence on occupation, which in turn influences material living conditions and health inequalities in Korea. It appears that occupation and education are stronger determinants of health in Korea than in other European countries.

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