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RISS 인기검색어
- 검색키워드
- 저자 : 서용희(Yong Hei Suhr) (검색결과 1 건)
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이두용(Doo Yong Lee),김병모(Byung Mo Kim),서용희(Yong Hei Suhr),최진정(Jin Jung Choi),한승수(Seung Soo Han),김광희(Kwang Hoi Kim) 대한내과학회 1987 대한내과학회지 Vol.33 No.6
N/A The present study was performed to evaluate the serum rGtp activity on ear1y detection and prevention of alcohol induced liver injury in 4184 persons with negative HBsAg, who live their common life. Prior to test we measured normal value of rGtp activity as contrast group among totals with numbers of 2226 (male 735, female 1491) which were HBsAg negative and no other LFT abnormality. In series of auther's test on teetotal group with cases of 2501 and habitual drinking group with cases of 1863 which were divided to 5 to 6 subgroups depending on daily amount, weekly frequency and total period in alcohol drinking respectively, we anlayzed comparatively the mean value and percentage of abnormality in rGtp, SGOT, SGPT and s-ALP in order to evaluate the efficacy of rGtp activity among each groups and teetoatla group and tested the influencing factor on rGtp. The results are summarized follows; 1) The mean values of rGtp activity in a normal contrast group were 17.9±11.0(SD) in male, 11.7±6.7 in female and 13.7±12.1 in total. 2) The total mean values of rGtp, SGOT, SGPT and s-ALP were 15.9±16.1, 17.25±7.8, and 54.2±25.6 in tee-total group and 33.6±43.0, 19.4±11.2, 22.4±18.5 and 55. 1±29.6 in habitual drinking group respectively, so the elevated rGtp, SGOT, SGPT and s-ALP in habitual drinking group compared to the teetotal group were obrained and statistically significant (p<0.05). Among each group of alcohol drinking the value of rGtp, SGOT and SGPT were increased tendency depending on increase in daily amount weekly frequency and toal period. 4) The rGtp activity was influenced by either of daily amount or weekly frequency or total period in alcohol drinking and we obtained by multiple regression test that most striking influencing factor on rGtp was weekly frequency of drinking. We concluded that rGtp is more sensitive than other liver function test in detection of alcohol-induced liver injury in a man who lives his common life and considered to be required to follow up rGtp activity as objective index to clearfy how to be influenced by abstinence of alcohol.
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