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서병조 에스케이텔레콤 (주) 2010 Telecommunications Review Vol.20 No.1
디지털 기술의 발달과 전송망의 광대역화로 융합 환경이 가속화되고 관련 기업들의 경쟁이 확대됨에 따라 융합시대의 성장동력으로 글로벌 미디어 그룹이 화두로 떠오르고 있다. 미국을 비롯한 해외 주요 국가들은 1990년대부터 방송산업 전반에 대한 규제 완화로 세계적으로 거대한 미디어 그룹을 탄생시켜 콘텐츠 제작부터 유통에 이르기까지 전세계 미디어 시장에서 지배력을 증가시키고 있는 반면 우리나라는 방송통신 산업의 성장 정체, 취약한 콘텐츠 산업 기반,FTA 시장 개방에 따른 경쟁 압력 등 여러 문제에 직면하고 있다. 이에 본 연구에서는 해외 주요 국가들의 미디어 산업 규제 현황분석을 토대로 우리나라에서의 글로벌 미디어 산업이 성장할 수 있는 정책방안이 무엇인가를 검토한다.
서병조,김태현,이주호,유항종,김진복 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.3
Benign papillary mesothelioma in peritoneum is very rare lesion which is often found incidentally in abdominal surgery. Gross findings are similar to dissemination of intraabdominal malignant lesion, so it is hard to make differential diagnosis between them. Benign papillary mesothelioma is not related with exposure of asbestos which is related with development of malignant mesothelioma. To make differential diagnosis between peritoneal seeding of malignant lesions and benign papillary mesothelioma, it is often necessary to do frozen biopsy during abdominal operation. The patient was 53-year-old man and was transferred to KGCC under the diagnosis of advanced gastric cancer in private clinic. In gastrofiberscopic examination. pylorus was completely obstructed with Borrman Ⅲ gastric cancer. Operation findings revealed complete obstruction of antrum and serosal invasion, enlargement of number 8 lymph node, 0.5㎝ sized multiple nodules in mesentery of small bowel and colon and frozen biopsies of nodules were made and no cancer cell was noted. We did radical subtotal gastrectomy with D2 lymph node dissection. Adjuvant chemotherapy with protocol(Picibanil 1.0K.E, Mitomycin 4㎎, 5-FU 500㎎) was started after 8 days of operation and discharged after 21 days of operation.
위선암에서 p53 단백의 과발현과 임상 및 병리학적 예후인자와의 상관관계
서병조,유항종,이주호,주미,이혜경,김진복 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.2
Objective: Mutations in the p53 gene, one of the most common genetic alterations in human cancer, are implicated in tumorigenesis and tumor progression. Wild-type p53 negatively regulates the cell cycle; a loss of function by mutation might be expected to result in enhanced proliferating activity and tumor progression. A large number of immunohistochemical studies have confirmed p53 accumulation to be a very common feature of human malignancy. The aim of the present study was to determine whether p53 status in gastric cancer is correlated statistically with various histopathological indicators or not. Methods and Materials: A total of 197 surgically resected gastric adenocarcinomas were examined to determine whether a correlation exited between immunohistochemical expressions of the p53 protein and other histopathological factors. Results: p53 overexpression was observed in 46.2% of the gastric cancers. Overexpression of p53 was correlated with vascular invasion of gastric cancer(p=0.004). In early gastric cancer, the p53 overexpression rate was 42.3%, and of them, a correlation was found between the intestinal type of the Lauren classifcation(p=0.013) and histologically differentiated gastric cancer(p=0.014). Conclusion: p53 overexpression was significantly correlated with vascular invasion of gastric cancer. In cases of early gastric cancer, p53 overexpression was correlated with Lauren classification and differentiation. These results suggest that p53 mutation plays an important role in carcinogenesis in gastric adenocarcinomas. Further study in needed to determine the correlation between p53 overexpression and the prognosis for the gastric cancer patient.
서병조,장석효,백인욱 인제대학교 1999 仁濟醫學 Vol.20 No.1S
베체트병은 반복되는 구강 및 생식기의 궤양, 안구의 염종 그리고 피부병변을 특징으로하는 전신적인 질환이다. 위장관의 궤양을 동반하는 소화기 베체트병은 전체 베체트병의 약 1%정도로 주로 말단 회장과 공장에 발발하나, 식도, 십이지장, 결장 및 항문직장부 등 장관 어디에나 궤양이 발생할 수 있다. 저자들은 1990년 이래 인제대학교 서울백병원 일반외과학 교실에서 수술을 시행한 소화기 메체트병 4예를 문헌고찰과 함께 보고하는 바이다. Behcet's disease is a systemic disease involving skin, joint, gastrointestinal tract, vascular and nervous systems characterized by recurrent oral and genital ulcerations and ocular inflammation. Although GI manifestations such as vomiting, abdominal pain, and diarrhea are present approximately in 50% of the patients, GI ulcers are not often demonstrated. Behcet's disease with GI ulcers, so called Intestinal Behcet's disease, account for about 1∼2% of Behcet's disease. The intestinal ulcers are frequently found in the terminal ileum and the cecum. Because intestinal ulcers in this disease tend to perforate at multiple sites, surgery is often performed for intestinal ulcers. Resection of ileocecal region or right half of the colon is usual procedures. We experienced 4 cases of intestinal Behcet's disease which was cured successfully by surgical treatment.