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서만욱,Seo, Man-Wook 대한수면의학회 1999 수면·정신생리 Vol.6 No.2
Headaches and sleep problems are common complaints in clinical practice. The relationship of sleep and headache has been extensively studied. Brain systems involved in the regualtion of sleep may also play a role in the initiation of vascular headache. Some of the physiological alterations in sleep, particularly REM sleep, are similar to those described in vascular headache. Clinical studies have documented an association between vascular headache and sleep, and headache is a common symptom of sleep disorders. Sleep and headache are known to be interrelated in several ways. It can be summarized as follows: 1) sleep-related headaches, 2) sleep phase-related headaches, 3) length of sleep(excess, lack, and disruption) and headaches, 4) headache related to sleep associated behavior, 5) sleep disorders and headaches, 6) effects of headaches on sleep, and 7) dreams and headaches. Several mechanisms can be proposed to explain the relationship between sleep and headaches.
오병철 ( Byeong Cheol Oh ),서만욱 ( Man Wook Seo ) 전북대학교 의과학연구소 2001 全北醫大論文集 Vol.25 No.1
저자들은 안면부 통증과 감각저하를 내원한 환자들에서 원인으로 각각 종양과 외상인 경우를 경험하였고, 병변의 해부학적인 위치가 각각 해면정맥동과 하안와열인 것을 알았으며, 각 질환의 예후를 추정해보았다. Isolated facial numbness usually indicates involvement of the trigeminal sensory system. The numb cheek syndrome, isolated cheek and gingival numbness, has many causes. The numb cheek syndrome can be a serious neurologic symptom, because it may suggest an underlying neoplastic etiology. Two patients developed facial pain and numbness. The first patient had headache and left cheek numbness which were associated with cavernous sinus tumor. The second patient had mild headache and left cheek numbness which was complicated with previous trauma. The fracture involved inferior orbital fissure. It is possible that the lesion related with numb cheek syndrome could be located at various parts of the trigeminal nerve branches, mainly at infraorbital nerve. Various diseases involving branches of trigeminal nerve could develop numb cheek syndrome, as well as neoplasm.
증예(症例) : 심내막염성 색전성 뇌졸중 환자의 혈전용해치료
김기주 ( Ki Ju Kim ),서만욱 ( Man Wook Seo ),김영현 ( Young Hyu Kim ),신병수 ( Byoung Soo Shin ) 전북대학교 의과학연구소 2010 全北醫大論文集 Vol.34 No.2
급성기 뇌경색의 치료는 정맥내 또는 동맥내 혈전 용해술을 이용하여 급성기 혈관폐색을 일으킨 혈전을 제거함으로써 이루어 진다. 감염성 심내막염 환자에서 발생한 색전증에 의한 급성기 뇌경색 환자에서 정맥내 및 동맥내 혈전 용해술을 이용하여 성공적으로 치료 할 수 있었다. 향후 심내막염 환자의 색전성 뇌경색 치료에 대한 혈전용 해술의 유용성은 더 많은 증례를 통해 연구되어야 한다. Stroke is a common neurologic manifestation in septic emboli caused by infective endocarditis and showed fatal outcome. The standard treatment modality of acute ischemic stroke is intravenous and/or intraarterial thrombolysis depend on onset to door time. However, the critical role of acute thrombolysis in acute stroke caused by septic emboil is unknown. We report a 26-year-old woman present with hemiparesis of right side and global aphasia. She had been suffering from common cold during five days. She was diagnosed as embolic occlusion of left internal carotid artery secondary to infective mitral endocarditis. After successful treatment with acute thrombolysis, her neurologic manifestations were improved. In our patient, acute thrombolysis to stroke due to infective endocarditis had been a therapeutic effect for recanalization of occluded vessel.
증례(症例) : 뇌경색, 발작, 인지저하로 발현한 하시모토 뇌병증 1예
오선영 ( Sun Young Oh ),임의성 ( Eui Seong Lim ),서만욱 ( Man Wook Seo ),김영현 ( Young Hyun Kim ) 전북대학교 의과학연구소 2004 全北醫大論文集 Vol.28 No.2
In recent years, encephalopathy has increasingly been recognized as a complication of Hashimoto`s thyroiditis. Patients with Hashimoto`s encephalopathy have variable neurologic symptoms such as stroke-like episodes, stupor, seizures, psychosis, tremor, myoclonus, and even myelopathy. Although they are usually euthyroid, their symptoms are not peculiar, and treatable with corticosteroids. And the symptoms of Hashimoto`s encephalitis resemble to Creutzfeldt-Jakob disease, However, the diagnosis of the patients with unexplained neurologic deterioration is a challenging task. We herewith describe a patient who displayed symptoms of Hashimoto`s thyroiditis associated with acute stroke, seizure attack, and cognitive impairment. The patient was treated with corticosteroids, and the response to steroids was excellent.
중추 및 말초신경손상 환자에서 교감신경 피부반응의 특성
김연희 ( Yun Hee Kim ),양선호 ( Sun Ho Yang ),고명화 ( Myoung Hwan Ko ),서만욱 ( Man Wook Seo ),황평한 ( Pyoung Han Hwang ),서정환 ( Jun Hwan Seo ) 전북대학교 의과학연구소 2001 全北醫大論文集 Vol.25 No.2
Objective: To assess the changes of autonomic nervous system in the patients with central and peripheral nervous system lesions using sympathetic skin response(SSR). Method: 55 patient group consisted of 18 stroke, 20 radiculopathy, 10 spinal cord injury, 5 carpal tunnel syndrome and 2 traumatic brain injury. Control group consisted of 22 healthy subjects without neurologic disease. Electrical stimuli were applied over the median nerve at wrist and SSR were recorded simultaneously on bilateral palms and soles. SSR that was not evoked by 5 times of stimulation was considered as no response. Results: 1) 27.7 percent of the patients with stroke and 60 percent of the patients with spinal cord injury showed no response. 2) The amplitudes of SSRs recorded in the affected palms of stroke patients were significantly smaller than these of control group (P<0.05), regardless of stimulation side. 3) The amplitudes of SSRs recorded in the unaffected palm of stroke patients when stimulus was given to the affected side were smaller than these of control group (P<0.05). 4) In the patients with radiculopathy and carpal tunnel syndrome, the latency and amplitude of SSR showed no significant difference compared with these of control group (P>0.05). Conclusion: In central nervous system lesion, the abnormal findings of SSR reflected abnormal ascending and descending pathways of autonomic nervous system. In the patients with radiculopathy, the autonomic nervous system seemed to be maintained normally.