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급성 심근경색증의 진단에 있어서 혈청 LDH Isoenzyme 의 의의
박인호,주우식,변흥수,최덕례,허갑도 대한내과학회 1986 대한내과학회지 Vol.30 No.5
The Serum total LDH activity and LDI-I isoenzyme determination were performed in 96 patients with a history suggesting acute myocardial infarction and 22 healthy control subjects. They were divided into 3 group based on their diagnosis. Group I included 31 patients with diagnosis of acute myocardial infarction, group Ⅱ 65 patients in whom the diagnosis of acute myocardial infarction was excluded, and group Ⅲ 22 healthy control subjects. Comparing the H-LDH percentage, H-LDH/M-LDH ratio, LDH 1/LDH 2 ratio, the results were as follows: 1) In group I 31 patients, the mean value of serum H-LDH percentage exceeds 80% and mean. valve of serum H-LDH/M-LDH ratio exceeds 4.0, showing singnificant higher value than that in group Ⅲ (P$lt;0.001) but no significant higher value between group Ⅱ and group Ⅲ was seen. 2) The mean value of LDH 1/LDH 2 ratio of 31 patients in group I was 1.45, showing significant higher value than that in group Ⅲ (p$lt;0. 001) but that of 65 patients in group Ⅱ showed significant higher value than that in group Ⅲ (p$lt;0.0l). 3) The serum LDH 1 percentage, LDH 1/LDH 2 ratioin in group I was not significantly correlated with that of total LDH.
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