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白善行 中央醫學社 1967 中央醫學 Vol.12 No.6
The author investigated on the electrolyte and acid-base balance variation in dogs as effected by pentothal anesthesia, and pneumonectomy with blood transfusion or 5% dextrose infusion. The 1st group, consisting of 7 dogs, served as a control group and subjected to pentothal anesthesia the 2nd group, of 8 dogs, received pneumonectomy with blood transfusion, and the 3rd group, of 7 dogs, received the same surgical intervention with 5% dextrose infusion, with the following conclusions. 1). Intravenous pentothal anesthesia brings slight respiratory as well as metabolic acidosis. 2). Pneumonectomy under intravenous pentothal anesthesia also brings acidosis, which can be compensated slightly by the blood transfusion and 5% dextrose infusion, the former being a little more effective than the latter. 3). The blood Hb and HCO3 decrease in all groups with elevation of pCO, and regression of buffer bases as well. 4). The blood Cl- and HP04- decrease a little with the induction of anesthesia onward, which can be compensated by the blood and dextrose infusion, the formor being more effective with respect to HP04- compensation. 5). The blood Na+, K+, and Ca# decrease under anesthesia, the compensation of which can be done with the blood transfusion more effectively than the 5% dextrose infusion in pneumonectomy. In summary, anesthesia per se, essential to the surgical intervention, has a little influence over the electrolyte and acid-bass balance; and the surgical measure like pneumonectomy can also bring significant variations in the electrolyte and acid-base blance through thereduction in the concentration of blood anions and cations, It is confirmed that these variations can be compensated by the blood transfusion, while the 5 % dextrese infusionn alone can not meet the purpose leaving a serious influence in the post-operative period.
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