다낭성 난소 증후군을 이환하는 난임 환자에서 통합 의학 치료의 효과 : 체계적 문헌 고찰 및 메타분석

배주은,박경덕,윤영진,Bae, Ju-Eun,Park, Kyung-Dug,Yoon, Young-Jin 대한한방부인과학회 2017 大韓韓方婦人科學會誌 Vol.30 No.4

Objectives: The purpose of this study is to investigate the effect on both herbal medicine periodic therapy and western medicine for polycystic ovary syndrome subfertility. Methods: We searched 8 electronic databases and search keywords were 'PCOS' and 'periodic therapy' or 'cyclic treatment'. We included randomized controlled clinical trials (RCTs) using the periodic therapy combined western medicine for PCOS patients. Results: We selected 8 studies. In studies, there were three studies in which the menstrual cycle was divided into 2 periods, one study divided into 3 periods, and four study divided into 4 periods. The meta-analysis of the 7 trials indicated that pregnancy rates integrated clomiphene and periodic therapy were higher than clomiphene alone. Conclusions: The periodic therapy combined western medicine for PCOS subfertility patients seems to improve pregnancy rates from this research. However, this result should be taken cautiously by unclear risk of bias. It would be necessary to fulfill further clinical study with herbal medicine periodic therapy on PCOS in Korean medicine to establish standard evidence of them.

월경통의 한약 주기 요법 치료에 대한 중의학의 임상연구 동향

배주은 ( Ju-eun Bae ),박경덕 ( Kyung-dug Park ),윤영진 ( Young-jin Yoon ) 대한한방부인과학회 2017 大韓韓方婦人科學會誌 Vol.30 No.1

Objectives: This study was performed to review the research trends in the periodic therapy of dysmenorrhea in traditional Chinese medicine (TCM). Methods: We searched articles in Chinese Academic journal (CAJ). Search key words were `dysmenorrhea` and `periodic therapy or cyclic treatment`. Results: We selected 6 studies except unrelated studies. According to study design, study was classified into 1 single group before after study and 5 randomized controlled trials. According to dysmenorrheal type, study was classified into 4 studies on primary dysmenorrhea and 2 studies on secondary dysmenorrhea. In the selected studies, there were four studies in which the menstrual cycle was divided into 2 periods, one study divided into 3 periods, and one study divided into 4 periods. The most used herb was “Angelicae Gigantis Radix”, “Cinnamomi Cortex Spissus”. All studies showed effective results on dysmenorrhea. Conclusions: In TCM, Research on periodic therapy of dysmenorrhea was being conducted more actively than Korean medicine. The periodic therapy seems to be effective on dysmenorrhea from this research. It would be necessary to fulfill further clinical study with periodic therapy on dysmenorrhea in Korean medicine to establish standard evidence of them.

갱년기증후군 환자의 안면홍조 증상과 맥 에너지와의 상관성 연구

배주은 ( Ju-eun Bae ),이희윤 ( Hee-yoon Lee ),손보길 ( Bo-gil Son ),윤영진 ( Young-jin Yoon ) 대한한방부인과학회 2016 大韓韓方婦人科學會誌 Vol.29 No.4

Objectives: The purpose of this study is to analyze the correlation between the pulse energy and hot flush in women who complain of climacteric syndrome. Methods: We analyzed the values of pulse energy on 78 of perimenopausal and postmenopausal women. The symptoms of patients were assessed by Kupperman`s index (KI) and Menopause Rating Scale (MRS). Statistical analysis was performed by Spearman correlation coefficient and student T-test, using SPSS 18.0 for window program. Results: The results were as follows. 1. There were no statistically significant relation between pulse energy of left Cheok subtracted from left Chon and KI, MRS hot flush score. 2. When divided depending on MRS hot flush score, There were no statistically significant differences on pulse energy. Conclusions: The results suggest that there is no correlation between hot flush score and pulse energy.

임신오조 환자의 맥파 분석 예비 연구

배주은 ( Ju Eun Bae ),윤영진 ( Young Jin Yoon ) 대한한방부인과학회 2015 大韓韓方婦人科學會誌 Vol.28 No.4

Objectives: The purpose of this study was to analyze the characteristics of the pulse energy in women who complained mild hyperemesis gravidarum. Methods: We analyzed the values of pulse energy on 14 patients who suffered mild hyperemesis gravidarum. The patients`` symptoms were assessed by PUQE (Pregnancy-Unique Quantification of Emesis scale). Statistical analysis was performed using SPSS 18.0 for window program, one way ANOVA, pearson correlation coefficient. Results: The results were as follows. 1. There were no statistically significant pulse energy differences. 2. The Chon pulse energy showed negative correlations with each Kwan and Cheok. 3. PUQE score showed positive correlations with right Chon pulse energy and negative correlations with right Kwan pulse energy. Conclusions: The result suggested that PUQE score changes be positive related with spleen pulse energy and negative related with lung pulse energy.

Polycystic Ovary Syndrome(PCOS) 환자의 맥 분석 연구

박경덕,배주은,윤영진,Park, Kyung-Dug,Bae, Ju-Eun,Yoon, Young-Jin 대한한방부인과학회 2017 大韓韓方婦人科學會誌 Vol.30 No.4

Objectives: The purpose of this study is to analyze the characteristics of the pulse energy in women with PCOS (Polycystic ovary syndrome) compared with women who have a regular menstrual cycle. Methods: We analyzed the values of pulse energy on 20 patients with PCOS as an experimental group and 40 patients with regular menstrual cycle as a control group. Control group was divided into 20 women with follicular phase and 20 women with luteal phase respectively. Statistical analysis was performed using SPSS/Win 18.0, one way ANOVA and Tukey HSD. Results: The results were as follows. 1. The mean pulse energy of the Right Chon was significantly increased compared with those of the Left Kwan and the Right Kwan among PCOS group. 2. There were no statistically significant pulse energy among control groups. Conclusions: The pulse energy of Lung is bigger than that of Spleen and Liver in PCOS patients compared with women who have a regular menstrual cycle.

친수공간개발의 물리적 계획요소가 인접지역에 미치는 영향 분석

홍지수(Hong, Ji-Su),배주은(Bae, Ju-Eun),김종구(Kim, Jong-Gu) 한국도시설계학회 2016 도시설계 : 한국도시설계학회지 Vol.17 No.6

본 연구는 친수도시 에코델타시티 개발 계획요소가 인접지역의 공간 및 물리적 시설 변화에 미치는 영향을 예측하였다. 가설설정으로 첫째, 친수도시가 조성됨에 따라 하천을 공유한 인접지역에 공간 및 물리적 파급효과를 가져오며, 둘째, 직접영향권과 간접영향권을 구분하여 각각에 대한 영향을 미치는 요소 차이가 있을 것으로 예상하였다. 가설의 검증결과 인접지역으로의 공간 및 물리적 시설에 있어 상당한 영향이 있을 것으로 나타났으며, 직접영향권과 간접영향권으로의 영향 요소는 차이를 보였다. 명지신도시에는 국제업무지구 및 상업 · 업무지역과 연계한 접근성이 높은 교통계획이 요구되며 녹색교통망과 복합적 교통로를 확충해야 한다. 사상지역의 스마트시티 재생사업과 같은 노후공단 재생시, 에코델타시티 내 산업단지와 연계한 산업클러스터 구축이 필요하다. 또한 광역교통망 계획 수립이 상호 발전에 중요한 요소로 작용됨을 알 수 있었다. The purpose of this study is to estimate the effect of the development factor of a water - friendly city, the Eco Delta City on the spatial and physical change of adjacent areas. Hypothesis : 1) As a water-friendly city is constructed, spatial and physical ripple effects are brought about in adjacent areas sharing rivers. 2) it is expected that there will be significant differences in factors that affect each of the direct impacts and indirect impacts. As a result of the analysis, it was found that there was a significant influence on the spatial and physical facilities to the adjacent area, and the factors resulting direct and indirect influences were different. For Myeongji new town, highly accessible transportation plans linked with international business districts and commerce and business areas are required, and green transportation networks and complex transportation routes should be expanded. It is necessary to construct an industrial cluster linked to industrial complexes within the Eco Delta City when revitalizing the old industrial complexes such as Smart City renewal project of Sasang area. In addition, it is found that the metropolitan transportation network planning is important.

전반적 급진성 치주염 환자의 치주, 교정, 보철의 다학제간 접근에 대한 증례보고

차현정(Hyun-Jeong Cha),배주은(Ju-Eun Bae),조진현(Jin-Hyun Cho),서조영(Jo-Young Suh) 대한치과의사협회 2017 대한치과의사협회지 Vol.55 No.6

Generalized aggressive periodontitis cause intrabony pocket, loss of teeth, and severe alveolar bone defect. As a result, pathologic tooth migration occurs and esthetic problem happens according to this, especially on the anterior teeth of maxilla. The purpose of this study was to assess the multidisciplinary treatment including periodontics, orthodontics and prosthetics of a patient caused by generalized aggressive periodontitis. This study presents a case using full mouth periodontal treatment, immediate orthodontic treatment for 5 months, implantation with guided bone regeneration and free gingival graft , and prosthetic treatment. Treatments took totally 14 months. Periodontal indicators such as probing pocket depth, bleeding on probing, tooth mobility improved. Also, the patient was satisfied with the esthetic and functional improvement.

한약재의 에스트로겐 유사 활성에 대한 기초 연구

손보길 ( Bo-gil Son ),이희윤 ( Hee-yoon Lee ),배주은 ( Ju-eun Bae ),윤영진 ( Young-jin Yoon ) 대한한방부인과학회 2018 大韓韓方婦人科學會誌 Vol.31 No.4

Objectives: The aim of this review is to investigate studies on Estrogen-like activity and to contribute to the utilization of herbal medicines including phytoestrogens. Methods: Electric searches were performed with Pubmed from 2013 to June 2018, for the words, ‘herb and estrogen’, ‘traditional Chinese medicine and estrogen’, ‘Oriental medicine and estrogen’, and ‘Korean medicine and estrogen’. 49 papers are investigated and classified into ‘in vitro’, ‘in vivo’ and ‘in vivo and in vitro’ experimental studies. Results: 1. In vitro experimental studies have shown that estrogen-like effects of the components extracted from Rhei Radix et Rhizoma, Rubi Fructus, Sparganii Rhizoma, Epimedii Herba, Spatholobi Caulis, Evodiae fructus, Curcumae longae Radix, Ginseng Radix, Bupleuri Radix, Astragali Radix, Salviae Miltiorrhizae Radix, Puerariae Radix, Scutellariae Radix are present. 2. In vivo experimental studies have shown that estrogen-like effects of the components extracted from Phytolaccae Radix, Ligustri Lucidi Fructus, Alismatis Rhizoma, Notoginseng Radix, Puerariae Radix, Ginseng Radix, Cyperi Rhizoma, Cistanchis Herba, Cynomorii Herba, Granati fructus, Astragali Radix, Rehmanniae Radix Crudus, Epimedii Herba, Polygalae Radix, Artemisiae Annuae Herba are present. 3. In vitro and in vivo experimental studies have shown that estrogen-like effects of the components extracted from Cirsii Herba, Dioscoreae Rhizoma, Salviae Miltiorrhizae Radix, Cynomorii Herba, Cinnamomi cortex, Drynariae Rhizoma, Psoraleae Semen, Schisandrae Fructus, Epimedii Herba, Astragali Radix are present. Conclusions: Future studies will require additional research on numerous herbal medicines used in clinical practice.