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박형윤 ( Hyung Yoon Park ),박태호 ( Tae Ho Park ),정문철 ( Moon Chul Jeong ),유재학 ( Jae Hak You ),김계정 ( Kea Jung Kim ),이규백 ( Kyu Back Lee ) 대한피부과학회 2001 대한피부과학회지 Vol.39 No.9
Chume-Strauss syndrome is a rare systemic vasculitis diagnosed by the presence of any four or more of six criteria which include asthma, eosinophilia>10%. mono- or poly-neuropathy, nonfixed pulmonary infiltrate, paranasal sinus abnormality, extravascular eosinophils. In a 65 year-old-woman, multiple purpura and crusted ulcer with central necrosis were developed on the both extremities and buttocks 1 month ago, She has been suffered from asthma, sinusitis and recurrent pneumonia since ten years ago Laboratory findings showed hematuria, hypereosinophlia and hyperIgE. On the histological examination of ulcerative nodule on the right leg, leukocytoclastic vasculitis and many neutrophils and eusinophils around the cutaneous vessels were seen and the other findings were fibrinoid necrosis and thickening of vessels wall without eosinophilic granulomatous changes. Renal biopsy showed focal segmental glomerulonephritis and sclerosing nephritis. We report a rare case of Chung-Strauss syndrome with acute glomerulonephritis.
Phototrichogram 을 이용한 한국인 두피 모발 특성의 정량적 분석
유재학(Jae Hak Yoo),박형윤(Hyung Yoon Park),박태호(Tae Ho Park),김계정(Kea Jeung Kim) 대한피부과학회 2002 대한피부과학회지 Vol.40 No.9
N/A Background: Although the diagnosis of hair disease depends on the comparison of normal and abnormal findings, data on normal hair characteristics in Koreans have not been reported. We have developed some technical improvements on phototrichogram methodology to assess hair characteristics, Objective: This study was performed to quantify Koreans` hair characteristics at each site (eg, vertex, occipital, temporal) of the scalp according to the age and sex using the phototrichogram and to compare the differences of hair characteristics between Caucasian and Korean population. Methods: Hairs in the precisely defined circle at each (vertex, temporal, occipital) area of the scalp in 42 healthy volunteers (16 men and 26 women) were evaluated according to sex and age groups, respectively. Each circumscribed area of the scalp, centered with a dot tattoo to ensure reproducibility, were first shaved: The shaven area was first photographed just after shaving. Two days later, grouping pattern of grouped hair unit, total and anagen hair counts were determined from low magnification image. The linear hair growth rate (㎛/day) and hair shaft diameter were obtained from high magnification image. Results: The results can be summarized as follows: 1. The range of hair density was 119±13/㎠~137±12/㎠ in male and 92±24/㎠~139±23/㎠ in female. Hair density of the occiput was significantly higher that of temple. 2. The range of linear hair growth rate was 300±19㎛/day~319±27㎛/day in males and 289±17㎛/day~327±54㎛/day in females. Hair growth rate in each group decreased in order of vertex, occiput and temple. Most of the hairs on the vertex in older males have slower growth rate than in other groups. 3. The range of hair thickness was 70±6㎛~89±10㎛ in males and 75±7㎛~87±6㎛ in females. Hairs of the vertex in the older male group (age≥45 year-old) were thinner than those of the occiput. The population of thin hair (<40㎛) on the vertex in older males was 7.6% larger than that of other sites. 4. The range of anagen ratio was 91.0%~93.7% in males and 91.9%~94.1% in females. Conclusions: Lower hair density, larger hair diameter and slower hair growth rate were remarkable in Koreans than in Caucasian. In addition, considering the hair characteristics of Koreans, the newer, improved method of phototrichogram will be a promising tool in the study of the hair disease including androgenetic alopecia, and in the quantitative analysis of the effects of agents stimulating hair growth. (Korean J Dermatol 2002;40(9):1035~1043)
박태호,유재학,정문철,박형윤,김계정 대한피부과학회 2001 大韓皮膚科學會誌 Vol.39 No.4
Granuloma annulare is a benign granulomatous disease which has an unknown etiology and it is represented by typical annular lesions. Recently various therapeutic modalities have been suggested such as intralesional injections of steroid, chloroquine, dapsone, surgical excision and so on. But any satisfactory result has not been reported yet. In the first case, a 65 year-old-man, Polycyclic, erythematous patches with raised edges were noted on the upper arm spreading to the trunk and both lower extremities for the past 3 years. In the second case, a 63-year-old man, numerous match-head sized skin-colored papules were detected on the sun exposed area such as both shoulders, upper extremities and hands dorsum for the past 3 months. On the histological examination of back, hands dorsum respectively, incomplete degeneration of collagen bundles surrounded by lymphocytes, histiocytes in a palisade pattern and a few giant cells were found in the dermis. Two patients were treated with systemic PUVA, one for 2months and the other, 4months.
박태호,유재학,정문철,박형윤,김계정 대한피부과학회 2001 大韓皮膚科學會誌 Vol.39 No.4
Nodular pseudosarcomatous fasciitis is characterized as rapidly growing benign tumor with microscopically resembling sarcoma in the upper extremities, especially forearms. Most lesions are located in the subcutaneous tissue, although these may also be found intramuscularly, with the involvement of the adjacent fascia or periosteum and dermis.
정유석,박형윤,박태호,유재학,김계정 대한피부과학회 2003 大韓皮膚科學會誌 Vol.41 No.1
Kaposi's sarcoma is a neoplasm of multifocal origin which manifests primarily as vascular nodules in the skin and other organs. Kaposi's sarcoma in iatrogenically immunocompromised patients is the result of immunosuppressive therapy in organ-transplant recipients, autoimmune disease patients and cytotoxic chemotherapy in cancer patients. We report a case of Kaposi's sarcoma in a 50-year-old man who developed well-defined purple-colored papules and plaques on both hands and feet after prednisolone treatment for underlying membranous glomerulonephritis. The histologic finding showed abnormally proliferated and dilated vessels, vascular slits, spindle-shaped cells and extravasated erythrocytes in the dermis. He was treated with cryotherapy, and the dosage of prednisolone was reduced. Improvement was seen in 6 weeks. (Korean J Dermatol 2003:41(1) : 135∼137)
After shave lotion 에 의한 색소성 접촉 피부염 1 예
유재학,정문철,박형윤,김계정,정유석 대한피부과학회 2002 大韓皮膚科學會誌 Vol.40 No.1
Pigmented contact dermatitis is characterized by a dark brown pigmentation that results from repeated exposure to small amounts of contact allergen. Histopathologic findings are liquefactive degeneration of the basal layer cells and melanophages in the upper dermis. We report a case of a 73-year-old man with dark brownish mottled hyperpigmented patches on the both cheeks and forehead. Patch tests were positive to isoeugenol, benzyl salicylate and after shave lotion. After shave lotion that the patient used maybe contain these fragrances. Improvement was seen 3 months after ceasing the use of after shave lotion.