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박자비 ( Ja Be Park ),정재일 ( Jae Il Chung ),윤진원 ( Jin Won Yoon ),설명도 ( Myung Do Seol ),원동준 ( Dong Jun Won ),조혜제 ( Hye Jae Cho ),이재진 ( Je Jin Lee ) 대한내과학회 2013 대한내과학회지 Vol.84 No.6
Esophageal neuroendocrine carcinomas are very rare and have a poor prognosis. In addition, the optimum treatment has not been established due to the rarity of the condition. An accurate differential diagnosis is important because treatments and clinical courses differ from those of esophageal squamous cell carcinomas. We report a case of a 61-year-old female who underwent endoscopy for dysphagia and was diagnosed with a neuroendocrine carcinoma of the esophagus, which was successfully resected by esophagectomy. (Korean J Med 2013;84:827-830)
증례 : 순환기 ; 유의한 관상동맥 질환이 없이 관상동맥 연축에 의해 발생한 심실세동 1예
박성균 ( Sung Kyoon Park ),김종상 ( Jong Sang Kim ),장재희 ( Jae Hee Jang ),서윤종 ( Yoon Jong Seo ),박자비 ( Ja Be Park ),주정철 ( Jung Chul Joo ),원동준 ( Dong Jun Won ) 대한내과학회 2009 대한내과학회지 Vol.77 No.6
일본과 마찬가지로 서양에 비해 이형 협심증의 발생률이 높지만, 아직 국내에서는 이형 협심증 환자에서의 관상동맥질환의 유무와 부정맥의 관계에 대한 통계나 연구가 부족한 상태이다. 이에 저자들은 의미있는 관상동맥 질환이 동반되어 있지 않았던 이형 협심증 환자에서 관상동맥 연축에 의해 발생한 심실세동 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Coronary vasospasm plays an important role in the pathogenesis not only of variant angina, but also of ischemic heart disease in general, including other forms of angina pectoris, acute myocardial infarction, and sudden death. Vasoactive events leading to an acute reduction in regional myocardial flow in the presence of a normal or previously compromised circulation are a common cause of arrhythmias. However, coronary vasospasm-induced electrical and mechanical complications are rarely reported in patients with angiographically normal or near-normal coronary arteries. This paper presents our experience with a patient presenting with coronary vasospasm-associated ventricular fibrillation without findings of significant coronary artery disease. (Korean J Med 77:759- 763, 2009)
증례 : 소화기 ; 원발성 간암의 신생물딸림증후군으로 표현된 다발성근염과 횡문근융해
서윤종 ( Yoon Jong Seo ),장재희 ( Jae Hee Jang ),박자비 ( Ja Be Park ),주정철 ( Jung Chul Joo ),정재일 ( Jei Il Jung ),조혜제 ( Hye Jae Jo ),곽재규 ( Jae Gyu Kwak ) 대한내과학회 2012 대한내과학회지 Vol.82 No.2
다발성근염은 사지 근위부의 골격근을 대칭적으로 침범하는 원인불명의 자가면역 질환으로, 악성종양과 동반된 사례가 보고되고 있으나 피부 근염에 비해 드물다. 이에 혼합간세포-담관상피암종으로 추정되는 원발성 간암의 신생물딸림증후군에 의한 횡문근융해와 다발성근염 1예를 경험하여 보고하는 바이다. Polymyositis is characterized by symmetrical proximal muscle weakness, nonsuppurative inflammation of skeletal muscle, elevation of muscle enzyme levels, and abnormality of electromyographical change. Its pathogenesis is unclear. Paraneoplastic syndromes are caused by malignant tumors, although not through direct effects of the primary tumor or its metastases. Several paraneoplastic syndromes, including erythrocytosis, hypoglycemia, and hypercholesterolemia, have been reported in patients with hepatocellular carcinoma. A few cases of polymyositis associated with hepatocellular carcinoma and one case of combined hepatocellular-cholangiocarcinoma associated with polymyositis and chronic hepatitis B virus infection have been reported. Skeletal muscle injuries without trauma, including metabolic myopathy, effects of certain drugs and toxins, infection, electrolyte imbalances, and endocrine disorders, may cause rhabdomyolysis. We present here a case of primary liver cancer associated with polymyositis and rhabdomyolysis. (Korean J Med 2012;82:212-216)