건선표피에서 Interleukin - 6항원의 면역조직화학적 연구

박의수,박관규,백원기,송준영 ( Eui Soo Park,Kwan Kyu Park,Won Ki Baek,Joon Young Song ) 대한피부과학회 1993 大韓皮膚科學會誌 Vol.31 No.5

소규모 제조업 사업장 남성 근로자의 수면의 질 및 관련요인

박의수(Park, Eui-Soo),신은숙(Shin, Eun-Sook),조영채(Cho, Young-Chae) 한국산학기술학회 2014 한국산학기술학회논문지 Vol.15 No.10

본 연구는 50인 미만의 제조업 근로자들의 수면의 질을 평가하고, 이들의 인구사회학적 특성, 건강행태 및 직업관련 특성과 수면의 질과의 관련성을 규명하고자 대전광역시 D공단에 소재하고 있는 50인 미만의 소규모 제조업 사업장 남성 근로자 856명을 대상으로 2011년 4월 1일부터 6월 30일까지의 기간 동안에 자기기입식 설문조사를 실시하였다, 조사내용은 조사대상의 인구사회학적 특성, 건강관련행위 특성, 직업관련 특성 및 한국판 PSQI를 사용한 수면의 질 평가 등이었다. 연구 결과, PSQI에 의한 수면의 질 평가에서 전체 조사대상자의 32.0%는 수면의 질이 좋은 것으로, 68.0%는 수면의 질이 좋지 않은 것으로 평가되었다. 위계적 다중회귀분석 모델에 의한 조사대상자의 수면의 질(PSQI) 수준은 기혼군일수록, BMI가 낮을수록, 주관적인 건강상태가 좋지 않을수록, 비흡연군, 음주군, 규칙적인 운동을 하지 않는 군 및 커피를 음용하는 군, 생산직 근로자, 주당 근무시간이 길수록, 질병으로 인한 결근 경험이 있는 군일수록, 외래진료경험이 있는 군일수록 유의하 게 낮았다. 위의 모델에서 보면 직업관련 특성이 추가됨으로 해서 13.1%의 설명력을 증가시켜 PSQI에 의한 수면의 질에 직업관련 특성이 높은 관련성이 있음을 시사하고 있다. This study was conducted to determine the quality of sleep, and its association with the sociodemographic characteristics, health-related characteristics, and job-related characteristics among male workers in small-scale manufacturing industries with fewer than 50 members. A self-administered questionnaire was distributed to 856 male workers from April 1st to June 30th, 2011. The survey items included the variables of sociodemographic, health-related, job-related, and quality of sleep. As a result, the quality of sleep according to the PSQI of the study subjects revealed 32.0% to be good and 68.0% to be poor. The quality of sleep assessed by hierarchical multiple regression analysis was significantly lower in the married group, those with lower BMI, and those with a lower level of subjective health status, non-smoking, alcohol drinking, without regular exercise, coffee drinking, blue color, had a longer of working hours, subjective health status, had a visiting out-patient department, and had a history of hospitalization. With the above model, the job characteristics had 13.1% explanatory power. This suggests that the quality of sleep (PSQI) has more power when combined with the job characteristics.

학교교육에 관한 교육철학회의 연구 성과와 전망 -1964년~2004년의 성과를 중심으로-

박의수 ( Eui Soo Park ) 교육철학회 2005 교육철학연구 Vol.0 No.33

피부 편평상피 세포암에서의 p53 단백표현에 관한 면역조직화학적 연구

박의수(Eui Soo Park),송준영(Joon Young Song) 대한피부과학회 1994 大韓皮膚科學會誌 Vol.32 No.6

Background : Mutations in the p53 gene are the most frecjuent genetic alterations found in human cancers to date. Bvidense suggests that wild-type p53 is a tumor suppressor protein, crucial for the negative regulative of cell cycling, and requiring loss of function mutations for tumorigenesis. Objective : Our purposr is to investigate the expression pattern of the p53 protein in the squamous cell carcinomas(SCCs) of the human skin. Methods : We studied p53 protein expression, using DO7 mnoclonal antibody immunohi-stochemistry, in 29 SCCs of the skin. Also, we compared the p53 expression depending upon with or without a history of UV exposure. Results : p53 immunoreactivity was observed in 48% (14 of 29) of SCCs and was not seen in normal skin. In 56% (16/29) SCCs the tumors were developed on UV-light exposure area. SCCs were divided on histopatal biological criteria in to three categories, well, moderately, or poorly differentiated. Although no significant differenie in the prevalence of p53 immunoreactivity was obierved between these groups, positive, strong staining was observed more frequently in poorly differentiated than in well-differe: treated tumors. Conclusion : Accumulat,i,on of p53 protein, suggestive in nessary cases of p53 gene mutation and hence loss of tumors upperesor function, may play a role in the tumorigenesis of SCCs. (Kor J Derrnatol 1994; 32(6): 9555-961)

한국 교육문제의 역사적ㆍ인식론적 탐구: 교과지식의 특성과 교육방법을 중심으로

박의수(Park, Eui-Soo) 고려대학교 교육문제연구소 2009 敎育問題硏究 Vol.0 No.35

이 연구의 목적은 한국의 교육문제를 역사적․인식론적 관점에서 고찰함으로써 우리 교육이 안고 있는 다양한 문제들의 근원과 본질이 무엇인가를 밝히는데 있다. 인식론적 관점이란 인간형성의 핵심을 이루는 교육의 내용 즉, 어떤 지식을 어떻게 가르치고 배우느냐, 그리고 그것이 삶과 어떻게 연관되느냐 하는 것을 중심 과제로 삼자는 것이다. 교과를 구성하는 지식의 성격을 분석하기 위하여 전통적인 지식의 유형과 현대의 개념들 즉, 권위적 지식, 규범적 지식,경험적 지식, 합리적 지식, 형식지와 암묵지, 방법적 지식, 과정적 지식 등의 개념을 사용하였다. 또한 교과 지식의 성격과 교육방법 및 인식과 실천의 관계 혹은 상호작용을 기준으로 원시 및 고대, 유교적 전통사회, 개화기, 광복 이후의 시기로 구분해 보았다.연구 결과 원시와 고대의 교육은 주로 암묵적 지식에 의존했고 앎과 삶, 교육과 생활이 하나로 통합되었으며, 유교적 전통교육의 기본 교과는 규범적․권위적 지식으로 인식과 실천, 지와 행이 통합되고 조화된 전일적 인격 형성을 이상으로 추구했으나, 과거제도가 정착되면서 인식과 실천이 유리되었다. 서구의 합리적․경험적 교과가 유입되는 개화기에는 서구적 근대교육과 유교적 전통 교육이 병행되는 과도기였으나 일제 강점기를 거치면서 전통교육은 급격히 사라지게 되었다. 해방 후 서구의 과학적 교과가 도입되었으나 유교적 규범적 교과를 교육할 때와 같은 방법으로 교육이 진행되었고, 시험위주의 교육이 확산되면서 합리적․경험적 지식조차도 교육현장에서는 권위적 지식으로 둔갑하여 인식과 실천의 괴리는 더욱 심화되었다. 또한 지식교육과 인성교육의 분리는 인성교육은 물론 지식교육의 부실을 가져왔다. 이는 결국 교육력의 약화를 초래하여 지식사회의 교육 경쟁을 약화시키는 근본적 원인으로 귀결되었다. The purpose of this study is to research the essential problems of Korean contemporary education. In order to that it took a historical and epistemological approach to Korean education problems. Epistemological approach means to study about the contents of education and how to teach students. In order to analyze the characteristic of subjects of curriculum, it took the traditional types of knowledge and some modern concepts of knowledge. And in order to historical approach, the historical period was divided into four periods. The result of study shows the following; ①primitive education depended on tacit knowledge and education integrated with knowledge and knowing, and living was united. ②Confucian education period was depended on normative․authoritative knowledge and the integration of knowing and living was important but according to establishment of recruit system with examination they were separated. ③The third period was transitional period. ④After liberation the education depended on rational․empirical knowledge but it was accepted as authoritative knowledge in the Korean classroom. The result of study found that knowing and living were originally one thing but they have divided into two and moreover knowledge education was separated from character education. So not only the knowledge education couldn't help the character education but also the knowledge education itself became ineffective and fruitless.

양성 대칭성 지방종증

박의수(Eui Soo Park),이원석(Won Seok Lee),송준영(Joon Young Song) 대한피부과학회 1989 대한피부과학회지 Vol.27 No.5

Benign symmetric lipomatosis is characterized by massive symmetric fat deposition, predominantly in the neck and shoulder girdle ares. We present a case of benign symmetric lipomatosis with alcoholic liver cirrhosis in a 54-year-old man. About two years ago, solitary skin-colored, non-tender swelling on the right upper arm was developed. The lesion had been aggravsted abruptly and rapidly in size and distribution since about one month ago. Histopathologic findings showed completely replaced reticular dermis and invaded subcutaneous tissue by mature fat cells.

한국 대학교육의 본질적 문제와 개혁의 방향

박의수 ( Eui Soo Park ) 교육철학회 2006 교육철학연구 Vol.35 No.-

악성 표피성 종양에서의 Epidermal Growth Factor Receptor 표현에 관한 연구

박의수(Eui Soo Park),송준영(Joon Young Song) 대한피부과학회 1994 大韓皮膚科學會誌 Vol.32 No.2

Background : Epidermal growth factor(EGF) usually stimulate she growth and proliferation of a variety of cell types in vitro and in vivo through binding to a peific cell surface receptor, a 170- kilodalton glycoprotein. The EGF receptor (EGFR) may be respansi ile for deranged keratinocyte proliferation and differentiation. Objective : Our purpose was to investigate the pattern of EGFR expression in malignant epidermal tumors. Methods : We performecl immunohistochemical studies to reveal immunoreactivity of EGFR in 7 basal cell carcinomas, 6 squamous cell carcinomas, and five nomal control skin using the Uectastain ABC immunoperoxidase stain system. Results : In normal skin, EGFR showed strong staining of basal cells and lower keratinocytes of the stratum malpighii. As squaous cells matured, staining gradually beame weaker. In all cases of basal cell carcinoma studied, there was loss of membrane labelling of the tumor cells and but in half the cases there was little or no siaining of the lesional cells. In squamous cell carcinomas, variable patterns were seen. The better differentiated tumors showed an essentially no mal pattern of EGFR expression. However, less well differentiated areas showed loss of membrane staining, cytoplasmic accumulation of receptor, and a heterogeneiy of staining intensity. Conclusion : Dysregulation of the EGFR may be important in the levelopment, of cutaneous epithelial malignancies but that giossly abnormal forms of the receptor do not occur. The quantitative and qualitative changes in EGFR that we have demonstrated may well be of importance in the pathogenesis of these keratinocyte tumors. (Kor J Dermatol 1994; 32(2): 271-276)

확장성을 갖는 u-Health 상황인식추론 모델

박의수(Eui-Soo Park) 한국의료정보교육협회 2013 보건의료생명과학논문지 Vol.1 No.1

Ubiquitous medical environment in the development of network technology and sensor technology, such as the emergence of u-Health has developed rapidly. Go to the members of the medical staff of the hospital and performed according to the network status information and business information, intelligently collect information that the hospital environment, situation analysis and development is required to manage the service. In this paper, context-aware reasoning model for smart hospital proposed. Defines the structure of the virtual space scalability and reusability of components capable of providing a mechanism to recognize a typical situation in a hospital environment when used for application development costs and scalability became.

"좋은 교육"의 준거에 관한 철학적 고찰

박의수 ( Eui Soo Park ) 교육철학회 2007 교육철학연구 Vol.38 No.-