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      • KCI등재

        간편한 선별검사법에 의한 농촌 노인인구의 백내장에 대한 역학조사

        박은규(Eun Kyoo Park) 한국안광학회 2000 한국안광학회지 Vol.5 No.1

        The purpose of this study is to determine the prevalence of cataracts in a rural area of Kyung - Buk province. Cataract is the main cause of blindness and visual impairment in the world. Recently, the number of age - related cataract surgeries has increased remarkably. In spite of such an increase in the number of patients, there are still many cataract patients with highly deteriorated visual function who have had no occasion to receive an ocular examination. In order to screen such patients the author assessed 636 individual(1272 eyes) aged 50 years or more who had wanted to be examined generally in two area. Chilgok and Munkyung, Kyung - Buk province using a simplified cataract screening system recently proposed by Sasaki et al, Kanazawa Medical University in Japan. The results obtained are as follows. The number of visual impairment patients in this study group was 493(77.5%). They were screened by cataract screening system. Primary screening examination detected 448 subjects to be suspected of cataract while the subsequent secondary sxamination narrowed this number of subjects to 308(48.4%). Final number of subjects to be diagnosed of cataract was 421(66.2%). The rate of incidence, according to the age, was 27.5% in the 50 year-olds age group, 62.5% in the 60`s age group, 86.1% in the 70`s age group and 94.3% in the 80`s age group and upwards. This results concluded that cataract is the main cause of blindness and visual impairment and is an improtant public eye health care problem of aged population in rural Korea. Methods of tackling the cataract problem(both backlog and incident), and other eye health needs are recommended. The need to extend eye health service to the rural areas is emphasized.

      • KCI등재후보

        7차 교육과정의 미술교과 교실에 관한 연구- 중학생들에게 미치는 교실의 영향력을 중심으로 -

        박은규(Eun Kyoo Park),장광집(Kwang Chi Chang) 경희대학교 산학협력단 예술디자인연구원 2016 예술· 디자인학연구 Vol.19 No.2

        본 연구는 2010년부터 전국적으로 확산된 교과교실제가본 목적에 맞게 활용되고 있는지에 대한 의문에서 출발한 연구이다. 교실은 학생들의 교육적 심리적 영향을 줄뿐만 아니라 교사의 교수·학습 및 흥미도 유발 등에 영향을 주므로 교육환경에서 보다 중요한 역할을 감당한다. 이러한 교실과 학생·교사의 관계를 7차 교육과정과 연계하여 교과교실제를 통해 환경의 영향력에 대해 밝혀내고자 한다. 교과교실제의 시설과 교구를 중심으로 다루어지며, 이 요소들을 분석하여 교육과정과 학생들의 활동영역 등이 어떻게 다른지 도출할 것이다. 특히 미술교과는 학생중심의 활동적 교육이 진행되어야 하는 교과로서, 선행 문헌과 교육부에서 지정한 운영 방안 등을 비교 분석하여 실태를 파악하고자 하였다. 따라서 본 연구는 미술 교과교실에 대한 현황을 분석하고, 7차 교육과정을 중심으로 하여 미술 표현활동을 능동적으로 이끌 수 있는 교실 환경의 구성에 대한 연구이다. In this study, a research nationally diffused subject classroom from 2010 I was starting from whether the question has been leverage looks to match. Classroom, educational of students, not only give a psychological impact, to influence, such as teacher of teaching and learning and interest also induce, in the educational environment, plays a more important role. In cooperation the relationship of these classrooms and students and teachers and 7 primary education curriculum and Serve to clarify the impact of the environment through the subject classroom system. Are treated at the center of the facility and the parish of the subject classroom system, by analyzing these elements, such as curriculum and student activities area is how different to derive either. Especially as the subject of art subject is that must be done by a vigorous education of the student center, I was trying to figure out the actual situation and comparative analysis of such prior art and management scheme that has been specified by the Ministry of Education, Culture, Sports, Science and Technology Ministry. Accordingly, in the present study, to analyze the current state of the art curriculum classroom, around the 7th curriculum is the study of the structure of the classroom environment that can lead to aggressive art expressive

      • 웨이브렛 변환의 모함수에 따른 ERG의 잡음제거 성능 비교

        서정익,박은규,장준영,Seo, Jung-Ick,Park, Eun-Kyoo,Jang, Jun-Young 한국임상보건과학회 2016 한국임상보건과학회지 Vol.4 No.4

        Purpose. Noise occurs at measuring Electoretinogram(ERG) signals as the other bio-signal measurement. It is compared the denoising performance according to the mother function of wavelet transforms. Methods. The ERG signal that generated power supply noise and white noise was used as a sampling signal. The noise of ERG signal was filtered by using haar, db7, bior mother function. The filtering performance of each mother functions was compared using Fourier transform spectrum and SNR(signal to noise ratio). Results. In the haar functioin, the result of the Fourier transform spectrum was that the power supply noise is removed and the white noise performance is not good. The SNR was 27.0404. In the db7 function, the results of Fourier transform spectrum was that the power supply noise is removed and the white noise performance is good. The SNR was 35.1729. In the db7 function, the results of Fourier transform spectrum was that the power supply noise is removed and the white noise performance is the bset. The SNR was 35.4445. Conclusions. The db7, bior function was good results in power supply noise and white noise filtered. The bior function is suitable for filtering noise of the ERG signal.

      • 시력교정술 부작용 인지도 조사

        이정영,서정익,박은규,Lee, Jeung-Young,Seo, Jung-Ick,Park, Eun-Kyoo 한국임상보건과학회 2016 한국임상보건과학회지 Vol.4 No.4

        Purpose. To investigate awareness of vision correction surgery side effects and investigated side effects affect vision correction surgery decisions. Methods. This study was performed on 85 college students. The awareness of vision correction surgery, the awareness of vision correction surgery side effects, and investigated side effects affect surgery decisions. Results. 37.6 % (32 people) replied that the drying effects is representative side effects of the eye correction surgery. 68.2% (58 people) answered the reason of eye surgery is uncomfortable wearing glasses. 74.1%(63 people) answered the side effects does not affect vision correction surgery decision. Prior to hear a description of side effects, 31.8% percent people hope the surgery. after listening to explain of side effects, only 10.6% percent people hope the surgery. Conclusions. People who want to get vision correction surgery should check their vision condition through prior examination and consultation. What side effects in the operation should be reviewed. That is the only way to reduce side effects.

      • KCI등재

        각·결막염 유발균에 대한 lysozyme 의 항균활성

        김대년(Dae nyoun Kim),박은규(Eun Kyoo Park) 한국안광학회 1997 한국안광학회지 Vol.2 No.1

        The cornea and conjunctiva of the human eye are exposed to external environment and thus are damageable. If the damaged part is infected with some pathogenic microorganisms, serious visual loss may be occured by inflammation. Keratitis or conjunctivitis does not always occur if the eyes are routinely exposed to pathogenic factors because lysozyme in human tears has antimicrobial activity against the microorganisms. In this study we have selected 5 strains causing keratitis and/or conjunctivitis, and cultured them in the optimum media. And then we have estimated the growth inhibition of the strains with the addition of various concentration of lysozyme to media to investigate the antimicrobial activity of lysozyme. The results are as follows. The growth of the strains were decreased according to the increase of lysozyme concentration. The growth of Pseudomonas, Neisseria, Klebsiella and Staphylococcus were in hibited 43%,41% and 22% respectively by 1mM concentration of lysozyme. The susceptibility of the gram-negative bacteria to lysozyme is 1.5-2 times higher than the lysozyme inhibited the growth of Fusarium which is fungi slightly.

      • KCI등재
      • KCI등재

        MMPH-0 (Enterobacter aerogenes)에 의한 6가 크롬 오염 지하수의 생지화학적 정화

        서현희,이성근,김강주,박은규,김영규,전철민,문지원,노열,Seo, Hyun-Hee,Rhee, Sung-Keun,Kim, Kang-Joo,Park, Eun-Gyu,Kim, Yeong-Kyoo,Chon, Chul-Min,Moon, Ji-Won,Roh, Yul 대한자원환경지질학회 2012 자원환경지질 Vol.45 No.2

        오염환경에 서식하는 토착미생물은 환경정화에 중요한 역할을 담당하며 이 연구는 6가 크롬 오염 지하수에서 분리한 미생물을 이용해 반응성, 이동성, 발암성 높은 6가 크롬을 당대사 조효소인 3가 크롬으로 환원/침전시켜 경제적, 친환경적, 생지화학적 정화의 효율성을 알아보았다. 미생물 농화배양과 조성분석, 호기와 혐기환경의 6가 크롬 환원과 내성, 전자공여체별 6가 크롬 환원, 지화학적 변화, 미생물 외형과 Cr((III) 침전물의 광물특성을 연구한 결과, 분리한 MMPH-0(Enterobacter aerogenes)는 혐기/호기환경에서 6가 크롬 내성과 환원능(유기산 주입 1주 후 70%, 주입 안한 경우 4주 후 10 ~ 20%)이 있고, Eh는 미생물의 유기산 산화로 생성된 전자에 의해 산화에서 환원환경, pH는 중성에서 약산성으로 변화되어 $Cr(OH)_3$/Cr(III)침전물이 형성되었다. SEM/TEM-EDS 결과 $2{\sim}5{\mu}m$ 막대형 미생물과 세포 밖 Cr(III) 침전물은 지화학적 환경변화와 유기산 산화에 따른 전자공여에 의한 환원의 근거가 된다. 지화학적 촉매제 토착미생물의 활성화로 산화환원에 민감한 중금속 오염 지하수 정화에 효율적 기술 응용이 기대된다. Indigenous bacteria isolated from contaminated sites play important roles to remediate contaminated groundwater. Chromium has the most stable oxidation states. Cr(VI) is toxic, carcinogenic, and mobile, but Cr(III) is less toxic and immobile. In this study, indigenous microorganism (MMPH-0) was enriched from Cr(VI) contaminated groundwater, and identified by 16S rRNA gene analysis. Using MMPH-0, the effect of stimulating with e-donors (glucose, lactate, acetate, and no e-donor control), respiration conditions, biomass, tolerance, and geochemical changes on Cr(VI) reduction were investigated in batch experiments for 4 weeks. The changes of Cr(VI) concentration and geochemical conditions were monitored using UV-vis-spectrophotometer and Eh-pH meter. And the morphological and chemical characteristics of MMPH-0 and precipitates in the effluents were characterized by TEM-EDS and SEM-EDS analyses. MMPH-0 (Enterobacter aerogenes) was able to tolerate up to 2000 mg/L Cr(VI) and reduce Cr(VI) under aerobic and anaerobic conditions. MMPH-0 performed faster and higher efficiency of Cr(VI) reduction with electron donors (over 70% after 1 week with e-donor, 10-20% after 4 weeks without e-donor). The changes of Eh-pH in effluents showing the tendency from oxidizing to reducing condition and a bit of acidic change in pH due to microbial oxidation of organic matters donating electrons and protons suggested the roles of MMPH-0 on Cr(VI) in the contaminated water catalyzing to transit geochemical stable zone for more stable $Cr(OH)_3$ or Cr(III) precipitates. TEM/SEM-EDS analyses of MMPH-0 and precipitates indicate direct and indirect Cr(VI) reduction: extracellular polymers capturing Cr component outside cells. These results suggested diverse indigenous bacteria and their biogeochemical reactions might enhance more effective and feasible remediation technology of redox sensitive heavy metals in metal-contaminated in groundwater.

      • SCOPUSKCI등재

        카드뮴이 카드뮴 내성 효모세포내의 효소 활성에 미치는 영향

        유대식,박은규,박정문 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.3

        카드뮴에 의하여 고도 카드뮴 내성 효모인 Hansenula anomala B-7 세포내 효소생성의 변화를 관찰하여 대사계의 변화를 추정했다. 1.0mM 카드뮴에 의하여 공시균의 alcohol dehydrogenase의 생성은 무첨가에 비하여 90% 이상 감소하나 malate dehydrogenase의 생성은 440% 증가되어, 카드뮴에 의하여 혐기적 대사계는 억제되고 호기적 대사계인 TCA 회로는 활성화되었다. 그리고 1.0 mM 카드뮴에 의하여 공시균의 해당계 효소인 phosphofructokinase의 생성은 약 40% 감소되었으나, 당의 호기적 분해대사계 효소인 6-phosphogluconate dehydrogenase의 생성은 약 136% 증가되어, 카드뮴에 의하여 EMP 대사계는 활성화되었다. 더욱이 1.0 mM 카드뮴에 의하여 공시균의 cytochrome c oxidase와 alkaline phosphatase의 생성의 각각 260%와 155% 증가되었다. 이상의 결과를 종합하면 카드뮴에 의하여 혐기적 대사계는 억제되나, 호기적 대사계는 활성화되며, 이로 인하여 생성된 다량의 NADH와 NADPH의 산화를 위하여 cytochrome c oxidase의 활성화는 필연적으로 요구되었다. 그리고 pyrimidine nucleotide 분해대사계 효소인 cytidine deaminase의 생성은 1.0mM 카드뮴에 의하여 약 86% 감소되어, 카드뮴은 necleotide 분해를 억제한다고 추측할 수 있었다. An extremely cadmium tolerant yeast, Hansenula anomala B-7 used to determine the modification of the intracellular enzyme activities by cadmium ion. The activities of alcohol dehydrogenase, phosphofructokinase, and cytidine deaminase were decreased up to 90%, 40%, and 86% compared with the control by mM cadmium nitrate respectively, but the activites of malate dehydrogenase, 6-phosphogluconate dehydrogenase, cytochrome c oxidase, and alkaline phosphatase were increased up to 440%, 136%, 260% and 155% compared with the control by 1 mM cadmium nitrate respectively. These show that the activities of the enzymes participating in Emboden-Mayerhof pathway (e.g. anaerobic metabolism) were reduced by cadmium, but those involved in hexose monophosphate pathway and tricarboxylic acid cycle (e.g. aerobic metabolism) were stimulated in contrast. It has been suggested that the diminished activity of cytideine deaminase in pyrimidine nucleotide dissimilation occured due to the inhibited nucleotide dissimilation by cadmium ion; the enhanced activity of cytochrome c oxidase was specifically required in order to oxidize a raised amount of NADH and NADPH due to the increased aerobic metabolism.

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