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      • KCI등재후보

        만성 신부전증 환자에서 신장 이식술 후 심기능의 변화

        김진오(Jin O Kim),박양규(Yang Kyu Park),박옥규(Ock Kyu Park) 대한내과학회 1991 대한내과학회지 Vol.41 No.6

        N/A To investigate the changes of the left ventricular function and its mechanisms after renal transplantion in chronic renal failure, M-mode echocardiography of the left ventricle (LV) was performed in 9 patients with chronic renal failure 71±87 days (mean±sd) before and 363±270 days after renal transplantation. After renal transplantation, arterial blood pressure didn't change significantly (151±20/98±7 mmHg versus 154±47/94±17 mmHg) but heart rate (79±17 beat/min versus 63±13 beat/min, p<0.01), BUN (54.4±13.1 mg% versus 23.0±11.9 mg%, p<0.01), serum creatinine (11.6±3.9 mg% versus 1.2±0.7 mg%, p<0.01) and serum potassium (4.9±1.1 mEq/L versus 4.2±0.6mEq/L, p<0.05) decreased significantly and hemoglobin in the peripheral blood (6.8±1.7 g% versus 11.5±1.6 g%, p<0.01) increased significantly. M-mode echocardiograms of the LV showed signifi- cant reduction of end-diastolic dimension (5.55±0.45 cm versus 5.21±0.58 cm, p<0.01), end-diastolic thickness of the LV wall (1.11±0.17 cm versus 0.83±0.10 cm, p<0.01) and LV mass index (308±104 g/m² versus 181±48 g/m², p<0.01). End-systolic wall stress of the LV didn't change significantly (126±20 g/cm² versus 134±94 g/cm²) but % fractional shortening (24±7% versus 34±8%, p<0.01) and heart rate-corrected mean velocity of circumferential fiber shortening (0.69±0.21 circ/sec versus 1.03±0.30 circ/sec, p<0.01) increased significantly and the relation between end-systolic wall stress and these indices of systolic function of the LV shifted upward. These results indicate that systolic function of the LV can improve after renal transplantation and this improvement of the systolic function is produced by the improvement of the myocardial contractility.

      • KCI등재후보

        승모판막협착증의 평가방법으로서의 연속파 Doppler 심초음파도와 심도자법의 비교연구

        김승관(S . G . Kim),박옥규(O . K . Park),강정채(J . C . Kang),박종춘(J . C . Park),정명호(M . H . Jeong),양승진(S . J . Yang),신순철(S . C . Shin),박상진(S . J . Park) 대한내과학회 1987 대한내과학회지 Vol.33 No.3

        N/A In order to evaluate the feasibility of the noninvasive continuous wave Doppler (CWD) echocardiographic technique in evaluating transmitral pressure gradient and the effective mitral valve area, the 17 patients with pure or dominant mitral stenosis were examined by CWD echocardiography and by cardiac catheterization technique. By CWD technique mean and peak transmitral pressure gradient were measured as 9.5±4.0 mmHg, 13.9±4.9mrnHg respectively, and the effective mitral valve area was calculated as 0.62±0.16 cm², while by standard fluid filled catheter system the mean diastolic pressure gradient between the pulmonary capillary wedge position and the left ventricle was measured as 12.2±4.1mmHg, and effective mitral valve area by Gorlin and Gorlin formula was calculated as 0.66±0,39 cm. Each of the mean and peak diastolic pressure gradient by CWD was significantly correlated with the pressure gradient measured by cardiac catheterization technique (r=0.61, r=0,55, p<0.05, p<0.05, repectively). Effective mitral orifice areas measured by either of the technique were well correlated (r=0.73, p<0.02). We concluded that noninvasive CWD technique could be an alternative method to the cardiac catheterization in quantitating the severity of mitral stenosis.

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