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금속작업자의 피부질환에 관한 연구 ( II . 알레르기성 접촉피부염 )
박종일 ( Jong Il Park ),김희옥 ( Hee Ok Kim ),박시룡 ( See Ryong Park ),오칠환 ( Chil Hwan Oh ),김순덕 ( Soon Duck Kim ),염용태 ( Yong Tae Yeum ) 대한피부과학회 1998 대한피부과학회지 Vol.36 No.2
Background: Skin contact with metalworking fluid(MWF) remains a frequent cause of occupational dermatitis. However, no precise data is available about sensitization in metalworkers exposed to MWF in Korea. Objectives : The purpose of this study was to evaluate the prevalence of contact sensitivity among metalwokers who handle MWFs and to investigate the suitability of a screening test with MWFs being actually used in metalworkers. Methods: An epidemiological study was performed using a ' questionnaire in 771 workers in 9 derpartments of a motor company. 278 out of 771 workers had actual contact with MWF. Patch tests were performed in 73 metalworkers who had suspected dermatits in relation to exposure of MWF, which was selected via interviews and dermatologic examinations. Patch tests were included with a routine series of common components of MWF(materials obtained from Chemotechnique, Sweden), a solvent series and several dilutions of various crude MWFs(8 species) Results : Contact sensitization was established in 14 metalworkers(5% of 278). Sensitising substances were biocide(6 cases), corrosion inhibitors(2 cases), emulsifiers(2 cases), biostatic substances(1 cses) and others(4 cases). Therefore 10 out of 14 metalworkers had true occupational allergic contact dermatitis. 10 out of 73 screening patch tests showed positive reactions to MWF elements, and 9 people who were positive to MWF elements showed positive reactions to crude MWF, but 1 person did not. Conclusion : The prevalence of occupational allergic contact dermatitis(3.5% of 278) was low. The screening patch test by crude MWFs actually used in metalworkers may give false negatives. Therefore for the purpose of diagnosis of allergic contact dermatitis, we need a process of patch tests with MWF elements. (Korean J Dermatol 1998;36(2) 246-251)
편평 황색종 , 건 황색종 , 결절성 황색종을 동반한 제 IIa형 과지질단백혈증
박종일,허광회,김희옥,박시룡 ( Jong Il Park,Kwang Hoi Hur,Hee Ok Kim,See Ryong Park ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.1
We report a case of a 59 year-old female with hyperlipoproteinernia who had xanthoma tuberosum, xanthoma tendinosurn and xanthoma planum. Yellowish nodules appeared on the right elbow 26 years ago and the lesions gradually increased in size and spread to the elbow, hand, knee, foot and achilles tendon. Except for the skin lesion, she was normal on physical examination. The laboratory findings showed that the serum cholesterol, beta lipoprotein and total lipid were increased. The beta band was rnarkedly elevated on electrophoresis, which suggested type IIa hyperlipoproteinemia. Histopathological findings shc wed many aggregates of foam cells and foreign body giant cells were seen in the dermis. (Kor J Dermatol 1997;35(1): 144-149)
박종일,박시룡,오진욱 대한피부과학회 2000 大韓皮膚科學會誌 Vol.38 No.11
Leukemia cutis has been said to occur in 13% of cases of AML(Acute myelogenous leukemia). Patients with AML have the highest incidence of both specific and nonspecific skin lesions, but leukemia cutis presenting with vesicobullous lesion are relatively rare. We report a case of a 50-year-old woman who showed leukemia cutis presenting with vesicobullous lesion.