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산모혈과 제대혈의 혈청 지질치에 영향을 미치는 요인에 대하여
민재희,정규혁,연제덕 한국환경보건학회 1997 한국환경보건학회지 Vol.23 No.3
To investigate the effect of several factors on serum lipids in maternal and infants umbilical cord blood, 111 cases of newborn infants and women delivered of a child who had delivered at hospital located in Chung-Ju city from Feb. 1, 1996 to Aug. 31, 1996 were studied. The gestational ages of cases were 37 to 42 weeks and the average maternal ages were 28.1$\pm$4.25 years old without any other medical or obstetric problems. No relationships between maternal consumption of coffee and maternal serum lipid levels were observed. However, serum total cholesterol and LDL-cholesterol levels in infants umbilical cord were significantly increased in proportion to increasing maternal consumption of coffee. The other factors such as alcohol drinking habits and residency affected maternal serum lipid levels and not serum lipid levels in infants umbilical cord. Delivery frequency showed very little or no effects on serum lipid levels in both maternal blood and infant s umbilical cord blood. In conclusion, maternal consumption of coffee significantly correlated with increasement of serum lipid levels in infants umbilical cord.
부산 내 미세먼지 고농도 지역 탐색 및 체내 휘발성유기화합물 바이오모니터링 조사
주현지,이승호,민재희,황용식,홍영습 한국환경보건학회 2023 한국환경보건학회지 Vol.49 No.6
Background: With its developed port and related industries, the concentration of fine dust is high in Busan compared to other cities in South Korea. Many studies have reported the health effects of fine dust, but there has been a lack of information regarding concentrations of volatile organic compounds among those who exposed to high levels of fine dust. Objectives: This study aimed to define an area with high concentrations of particulate matter and perform biomonitoring surveys among the residents of the area. Methods: Air quality data was collected and the mean level of each district in Busan was derived. We then defined the area with the highest concentrations of PM10 as a target site. Urine samples were collected from the 400 participants and analyzed for VOCs metabolites - trans,trans-Muconic Acid (t,t-MA) and N-Acetyl- S-(benzyl)-L-cysteine (BMA). Interviews were conducted by trained investigators to examine demographic information. The levels of t,t-MA and BMA were compared with representative South Korean population data (Korean National Environmental Health Survey). The association of the VOC metabolites and fine dust were analyzed by general linear regression analysis. Results: The mean of PM10 in the target site was 42.50 μg/m3 from 2018 to 2020. Among the 400 participants in the target site, 74.8% were female and the average age of the participants was 66 years. The geometric mean of t,t-MA was 71.15 μg/g creatinine and the BMA was 7.00 μg/g creatinine among the residents. The levels were higher than the geometric mean from the 4th KoNEHS. The levels of t,t-MA showed significance in BMI, smoking status, and household income. BMA showed significance in gender and age. Conclusions: Compared to the general population of South Korea, the target site’s residents had higher biomonitoring levels. Based on this study, continuous screening for high risk areas, including the target site, and biomonitoring of the residents are required.