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증례 : 류마티스 ; 전신홍반루푸스의 비장경색으로 처음 발현된 항인지질 증후군 1예
정혜윤 ( Hye Yun Jeong ),강산하 ( San Ha Kang ),송지현 ( Ji Hyun Song ),신선영 ( Sun Young Shin ),민다니엘 ( Daniel Min ),한규현 ( Kyu Hyun Han ),최진정 ( Jin Jung Choi ) 대한내과학회 2014 대한내과학회지 Vol.86 No.5
좌상복부 통증을 호소하는 전신홍반루푸스 환자에서 항인지질 항체 양성 소견과 함께 비장경색이 단독으로 발생된 증례로 혈전증의 다른 위험 요인을 배제한 후 항인지질 항체 증후군으로 진단한 1예를 경험하였기에 보고하는 바이다. Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. In patients with SLE, the prevalence of antiphospholipid antibodies is considerably higher, and is largely responsible for thrombosis. Splenic infarction is a rare complication of arterial thrombosis in patients with SLE. It is important to consider splenic infarction in a patient with SLE complaining of left upper quadrant (LUQ) pain because of the possibility of severe infarction-related complications, such as subcapsular hemorrhage and splenic rupture. We report a case of solitary splenic infarction in a patient with SLE. The only symptom was LUQ pain of 3-day duration. Lupus anticoagulant activity was positive and abdominal-pelvic computed tomography (CT) was consistent with splenic infarction. She did not show any other evidence of thrombotic events. The patient was diagnosed with antiphospholipid syndrome that presented as a splenic infarction in a SLE patient. (Korean J Med 2014;86:651-654)