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RISS 인기검색어
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- 저자 : 문용식 ( Yong Shig Moon ) (검색결과 4 건)
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최석준 ( Suck Jun Choi ),채정룡 ( Jeong Ryong Chae ),문용식 ( Yong Shig Moon ),최태석 ( Tae Suck Choi ),심미령 ( Mi Ryeong Sim ),최석채 ( Suck Chei Choi ) 한국운동영양학회 2004 Physical Activity and Nutrition (Phys Act Nutr) Vol.8 No.2
The purpose of this study was to determine the effect of long distance running on the level of gastrointestinal hormones such as gastrin which stimulates the secretion of gastric acid, insulin and glucagon which affect glucose metabolism as well as the level of glucose. Method: Twenty four long distance runners (male 16, female 8) participated in this study. Studies were performed after an overnight fasting. The levels of gastrin, insulin, glucagon, and glucose in blood were measured at 30min before and after exercise, and then they were measured again at 24 hr after 10 km race. Result: Plasma gastrin level was increased immediately after exercise (p<0.05), while no significant changes were observed before and after 24 hours of exercise. Plasma insulin level was decreased immediately after exercise (p<0.05). Plasma glucagon level was elevated immediately after exercise (p<0.05). However, there was no significant difference in the level of plasma glucose level during the study period. Conclusion: These results indicate that the elevated level of gastrin in long distance runner may be involved in acid-related gastrointestinal disease. The changes of insulin and glucagon levels may represent the constant blood glucose level and further imply the fine regulatory mechanism of glucose homeostasis in blood during short time exercise in long distance runners.
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文溶植 中央醫學社 1962 中央醫學 Vol.2 No.3
The accelerating action of adrenalin on blood coagulation was first noticed by Vosburg & Richards and the effect was confirmed later by many others, -however, on its mechanism their postulations were diverse. Vosburg took the increase of blood sugar by adrenalin as the cause, and Cannon & Gray claimed that liberation of accelerating element from liver into blood would bring shortening of blood clotting time, and Grabfield reported the increase of prothrombin in circulating blood. On the accelerating mechanism of blood coagulation in vivo, our coworkers in our laboratory have confirmed that the acceleration induced by stimulants was due to the increase of serum lipids (phospholipids and cholesterol) which took part in thromboplastin generation, and were probably liberated from adrenal cortex. Author intended to certify whether the acting mode of adrenalin was related to the adrenals and pituitary or not. Albino rabbits weighing about 2kg were used. Adrenalin hydrochloride was infused 0.01-mg/kg of body weight into ohr vein, and blood samples were withdrawn from juglar vein every 15 minutes for 1-2 hours after adrenalin infection. Observations were performed in 3 groups (normal, adrenalectomized, and hypophysectomized rabbits). Determination of blood clotting time was done by Lee & White's method. Serum total cholesterol was calculated by Zak's method. Adrenals were studied hystochemically for lipids by Sudan I -staining and for cholesterol by Schultze's test. Following Results were obtained. 1) The accelerating effect of adrenalin on blood coagulation accompanying with increase of serum cholesterol is inhibited in the adrenalectomized or hypophysectamized rabbits. 2) Adrenalin-induces marked depletion of lipids and cholesterol in the adrenal cortex mainly in zona fasciculata from normal rabbits, but such depletion is not observed in hypophysectomized rabbits.
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文溶植 中央醫學社 1962 中央醫學 Vol.2 No.1
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文溶植 中央醫學社 1962 中央醫學 Vol.2 No.2
Copper is known to be one of the essential trace minerals in the organisms as an integral part of some enzyme system and found utmost in the liver. It has been well shown by Herkel, Mallory and other workers that the liver is a site of prominent storage of copper after continued administration. Since important parts of metabolic process of carbohydrate take place in the liver, it seems to be quite possible that administration of copper would influence the blood sugar level. Materials and methods Albino rabbits weighing about 2kgs were used and they were infused with 0.5cc or 1.0cc of 1% CuSO4-solution per kg. b. w. intravenously. The determination of blood sugar level was performed every 30 minutes after infusion of CuSO4-solution by Hagedorn-Jensen’s method. To investigate the effect of copper on the state of adrenalin-hyperglycemia, the determinations of blood sugar levels were done in the animals treated with CuSO4-solution daily for 3, 5, 7, or 10 days followed by subcutaneous injection of 0.1cc of 0.1% adrenalin solution per kg. b. w. Following results were obtained. 1. Administration of copper sulfate alone does not influence blood sugar level in rabbits. 2. Adrenalin effect on blood sugar is more prominent and transient in the rabbit$ treated with copper sulfate. 3. Such effect of copper to adrenalin-hyperglycemia appears to be kept more than 2 weeks after cessation of its administration.
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