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성상신경절 차단이 혈장 ACTH 및 Cortisol 치에 미치는 영향
채영근(Young Geun Choi),송장호(Jang Ho Song),임현경(Hyun Kyung Lim),한정욱(Jung Wook Han),이성근(Seong Keun Lee),차영덕(Young Deog Cha),신재규(Jae Kue Shin),류중하(Jung Ha Ryu) 대한통증학회 2002 The Korean Journal of Pain Vol.15 No.1
N/A Background: Stellate ganglion block (SGB) is a sympathetic nerve block method which has been used most frequently in pain clinics due to its wide range of indications. This study was conducted to determine the endocrinologic response to repeated SGBs. Methods: Thirteen healthy volunteers were studied. SGB was performed one hunderd times with 6 ml of 1% mepivacaine. Venous blood was drawn to measure plasma adrenocorticotrophic hormone (ACTH) and cortisol consentration before and after SGB for twenty, forty, sixty, eighty and one hundred times. The blood was drawn at 8:00 a.m. and 4:00 p.m. every sampling day. Results: The plasma concentration of eortisol at 8:00 a.m. was significantly higher after SGB one hundred times than prior to SGB. The plsma concentration at 4:00 p.m. was significantly higher after SGB forty times than prior to SGB. The ACTH concentration was significantly times at 4:00 p.m. Conclusions: After SGB, the plasma concentration of cortisol tended to increase while the ACTH levels tended to decrease. However, the effects of endocrinologic response to SGB were unclear since all values were within the normal limit.