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피질골 골결손부에서 Oxidized Cellulose 피개의 영향에 관한 실험적 연구
김회종,임재석,Kim, Hoi-Jong,Rim, Jae-Suk 대한악안면성형재건외과학회 1998 Maxillofacial Plastic Reconstructive Surgery Vol.20 No.2
In dentistry, bony defects can be formed by cyst, tumor, inflammation, trauma and surgery in maxilla and mandible. If the overlying soft tissue invades and preoccupies the jaw bony defects, regenerated bony tissue same as adjacent bone can not replace whole space of the defects, thus preventing osteogenesis from occurring. Guided bone regeneration(GBR) is based on the prevention of overlying soft tissue from entering the bony defect during the initial healing periods. E-polytetrafluoroethylene(e-PTFE) is one of an effective and widely used barrier membrane for GBR, but it has the disadvantages such as surgical removal and high price. To overcome such disadvantages of e-PTFE, many investigators have proposed various absorbable barrier membranes. Inexpensive oxidized cellulose($Surgicel^{(R)}$) membrane was shown to have potential for use as an absorbable barrier membrane for regenerative procedure and it would not require surgical removal. The purpose of this study is to investigate the absorption periods of oxidized cellulose at the implant site and usefulness as a mechanical barrier, preventing the ingrowth of the overlying soft tissue into the bony defects. Two bony defects were made in each tibia of a dog using drill and one defect covered with oxidized cellulose and the other covered with periosteum directly as control. The experimental animals were sacrificed at 1st-7th, 10th, 14th, 21th, 28th day postoperatively, Inspection of the specimens was done to evaluate gross changes. Specimens were examined histopathologically by hematoxylin-eosin and Masson's trichrome staining under light microscope. The results were as follows : 1. There was no significant differences of inflammatory reaction between the experimental and the control group. 2. The resorption of oxidized cellulose was almost completed within 14th day. 3. Histologically, bone formation in the experimental group was somewhat more than that of the control group at 10th, 14th, 21th and 28th day postoperatively. The bone forming pattern of the experimental group was more regular than that of the control group. 4. There was no evidence of soft tissue invasion into the bony defect in the experimental group. In conclusion, oxidized cellulose membrane might be used as an alternative absorbable barrier membrane to prevent overlying soft tissue invasion into the bony defects.
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임재석(Jae Suk Rim),김석문(Suk Moon Kim),김회종(Hoi Jong Kim),김온(Onn Kim) 대한악안면성형재건외과학회 1989 Maxillofacial Plastic Reconstructive Surgery Vol.11 No.2
Osteopetrosis는 드물게 볼 수 있는 질환으로 일명, Albers-Schonberg disease 혹은 Marble bone disease 라고도 하며 그 주요한 특징은 전반적인 골경화증, 임파선의 증대, 간비 증대, 범혈구 감소증, 다발성 골절과 실명 등이다. 이 질환은 X-선상에서 독특한 소견을 보이며 임상적으로 악성형과 양성형으로 나눌 수 있다. Dominant form은 양성형으로써 다양하게 표현되어 단독 X-선상에서 이상을 나타내는 것부터 골절과 뇌신경을 침범하기까지 다양하게 나타나며, Recessive form은 악성형으로 자궁내에서 진단되어지고 빈혈이 심하며 골수양화생이 있으며, 감염 특히 하악의 골수염으로 대개는 첫 1 년 이내에 사망 한다고 보고되어 있다. 이에 저자들은 개인치과에서 상악 좌측 제 2대구치 발거후 골수염이 발생한 31세 남자 골석화증 환자를 치험하였기에 문헌고찰과 함께 보고하는 바이다. Osteopetrosis (Albers-Schonberg disease) is a rare disease characterized by generaized sclerosis of bones, hepatoslenomegaly, pancytopenia, multiple fracture, blindness. The disease shows characteristic radiographic feature and two rather well - defined patterns have been recognized, We experienced a case of osteopetrosis in a 31 year old man, who has had pus discharge and fetid odor after extraction of upper maxillary molar. We made a brief review of literature.
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