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전신홍반루푸스 환자에서 발생한 자발성 두개내 저혈압 증후군
신주영 ( Ju Young Shin ),박윤정 ( Yun Jung Park ),김선영 ( Sun Young Kim ),정의성 ( Eui Sung Chung ),고선희 ( Sun Hee Ko ),박정화 ( Chung Hwa Park ),김찬준 ( Chan Joon Kim ),김정호 ( Jeong Ho Kim ),조철수 ( Chul Soo Cho ) 대한류마티스학회 2009 대한류마티스학회지 Vol.16 No.3
Headaches are not only one of the 19 different neuropsychiatric syndromes in SLE but also the most common chief complaint of patients with neuropsychiatric lupus. Approximately 50% of patients with SLE are presumed to have neuropsychiatric phenomena during their illness. There`re no specific serological, radiological or histological biomarkers to confirm the clinical diagnosis of neuropsychiatric lupus. Therefore, physicians tend to try controlling lupus activity especially when the origins of the headache in patients with lupus are difficult to define. However, neuropsychiatric lupus can only be diagnosed after excluding other causes which is the point. A 47-year-old woman with lupus presented to the emergency department with the sudden onset of postural headache with nausea and vomiting. Through CSF tapping and CT myelography, intracranial hypotension with spontaneous CSF leakage was revealed. Her symptoms promptly improved after therapy using an epidural blood patch. Intracranial hypotension with spontaneous CSF leakage is rare disease, and it has never been reported in patients with SLE before. This case emphasizes the importance of finding out the origin of a headache in patients with lupus.
정수연 ( Soo Yeon Jung ),이미정 ( Mi Jeong Lee ),김찬준 ( Chan Joon Kim ),박정화 ( Chung Hwa Park ),장수선 ( Soo Sun Chang ),문수진 ( Su Jin Moon ),김완욱 ( Wan Uk Kim ) 대한류마티스학회 2010 대한류마티스학회지 Vol.17 No.1
Spontaneous visceral hemorrhage is a rare complication of systemic lupus erythematosus (SLE). We report here on a 55-year old male with SLE and who presented with acute abdominal pain due to bleeding of the hepatic artery and the splenic artery. Angiography revealed a spontaneous hemorrhage from branches of the hepatic artery and the splenic artery. We report here on a case of spontaneous recurrent non-traumatic hemorrhage of a visceral artery in a patient with secondary antiphospholipid syndrome (APS), and such a condition has not been previously described in a Korean patient with SLE.
천식환자에서 병발된 S 단백 결핍과 연관된 폐동맥 색전증
박정화 ( Chung Hwa Park ),윤승배 ( Seung Bae Yoon ),김대범 ( Dae Bum Kim ),이한희 ( Han Hee Lee ),김찬준 ( Chan Joon Kim ),김정호 ( Jeong Ho Kim ),고훈영 ( Hoon Young Ko ),이미정 ( Mi Jeong Lee ),이화정 ( Hwa Jeong Lee ),김승수 ( 대한천식알레르기학회 2010 천식 및 알레르기 Vol.30 No.2
Asthma is a chronic multifactorial disease with frequent exacerbations in many patients. Much effort has been made to determine prevalent factors associated with difficult- to-control asthma. Here we report the case of a 57-year-old man who was treated for asthma during the last 4 years at our pulmonology clinic. Recently, the patient experienced severe dyspnea for more than 3 months despite the addition of the leukotriene modifier, theophylline and oral cortic- osteroid. Chest CT scans revealed multifocal areas of pulmonary arterial thrombosis. Doppler ultrasonograms showed multiple deep vein thrombi. The patient was diagnosed of having protein S deficiency and was treated with low molecular weight heparin, followed by oral warfarin. Now, he has no pulmonary arterial thrombosis and has no more asthmatic attack for half a year. (Korean J Asthma Allergy Clin Immunol 2010;30:135-139)