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륙미지황탕가미방추출물(六味地黃湯加味方抽出物)이 골형성관련물질(骨形成關聯物質)인 OTN과 BMP2의 유전자전사활성(遺傳子轉寫活性)에 미치는 영향(影響)
김윤갑 ( Youn Kab Kim ),이응세 ( Eung Se Lee ),차윤엽 ( Yun Yeop Cha ) 한방재활의학과학회 2002 한방재활의학과학회지 Vol.12 No.3
We studied the effects of the Yukmigihwang-tang(added) on the bone morphogenesis such as OTN and BMP2 which are engaged in bone formation.The results of RT-PCR data are as follows.1.BMP2 gene of HOS-TE85 cell lines were accelerated about 50% as cultivated in 0.5% solution.2.OTN gene of MG-63 cell lines were accelerated about 20% as cultivated in 0.01% solution.3.OTN gene and BMP2 gene of KG-1 cell are generally accelerated in various condition