http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
임신에 의해 악화된 원발성 하지불안증후군(restless leg syndrome)의 치료
김시선 ( Shi Sun Kim ),안치옥 ( Chi Ok Ann ),조은규 ( Eun Kyu Cho ),심현진 ( Hyun Jin Shim ),김윤숙 ( Yun Sook Kim ),배동한 ( Dong Han Bae ),양광익 ( Kwang Ik Yang ) 대한산부인과학회 2010 Obstetrics & Gynecology Science Vol.53 No.10
Restless leg syndrome (RLS) is characterized by intense restlessness and unpleasant creeping sensations deep inside the lower legs, occurring during periods of rest, evening and night. These symptoms can be improved by movement. There are two different phenotypes of RLS. One early-onset form starts before 36 years old. It has mostly a familial history, severe symptoms, and highly genetically determined. And it is a highly dependent to iron level of the brain. The other delayed-onset form starts after 36 years old, mostly secondary, without familial history, with a rapid evolution in two or three years. And it is associated with frequent low ferritin level of serum. Pathophysiology of RLS remains incompletely understood. However, advanced studies suggest that RLS may be generated by dopamine dysfunction locally within the central nervous system. Dopaminergic agonists are the treatment of choice, if the symptoms are severe. And iron therapy improves RLS symptoms in iron deprived patients. Early detection during pregnancy is needed because RLS gives an important impact on sleep efficiency and quality of life. Recently we have experienced a case of primary RLS patient diagnosed at 24+3 weeks, treated by dopaminergic agonist ropinirole and iron. We describe this case with a brief review of the literature.
산전 초음파로 진단된 태반 기저층의 광범위 경색에 의한 태아사망
안치옥 ( Chi Ok Ahn ),김시선 ( Shi Sun Kim ),조은규 ( Eun Kyu Cho ),심현진 ( Hyun Jin Shim ),김윤숙 ( Yun Sook Kim ),배동한 ( Dong Han Bae ),양승하 ( Seoung Ha Yang ) 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.1
Placental infarction is a localized area of ischemic villous necrosis, resulting from interruption in maternal blood supply. These have been associated with postterm pregnancies, maternal hypertension, and anticardiolipin antibodies. Most are due to thrombotic occlusion of an uteroplacental artery. But, infarction in the basal layer of the placenta is very rare and characterized histologically by massive deposition of fibrin. The etiology remains uncertain. However, it has clearly associated with significant perinatal morbidity and mortality including stillbirth, preterm birth, and intrauterine growth restriction. This condition has been diagnosed by prenatal ultrasonography with hyperechoic areas along the maternal side, but extending through much of the placental tissue. Recently we have experienced a case of extensive infarction in the basal layer of the placenta diagnosed by prenatal ultrasonography at 17 weeks, resulted in stillbirth. We describe this case with a brief review of the literature.