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      • 경장영양을 공급받는 중환자의 위 잔여량 현황 조사

        박영옥 ( Young Ok Park ),강은희 ( Eun Hee Kang ),박소정 ( So Jung Park ),박민아 ( Min A Park ),윤소윤 ( So Yoon Yoon ),김승란 ( Seung Lan Kim ),박정윤 ( Jeong Yun Park ),정영선 ( Young Sun Jung ),홍석경 ( Suk Kyung Hong ),예병덕 ( 한국정맥경장영양학회 2009 한국정맥경장영양학회지 Vol.2 No.1

        Purpose: High gastric residual volumes (GRVs) are known to be one of the frequent causes of stopping enteral nutrition. This study was performed to investigate the gastric residual volume status in critically ill patients who were admitted to intensive care units. Methods: The subjects were 96 critically ill patients who were admitted to the ICU at ASAN Medical Center between October 1, 2008 and March 31, 2009. The measured volumes were categorized in 50 ml intervals from 0 to 500 ml. Results: Of the total GRVs measured, 46% were <50ml. The patients with a GRV ≥50 ml were 54% and 4% had a GRV ≥250 ml, whereas none of the patients` GRVs were ≥500 ml. When admitted to the hospital, There was a correlation between the APACHE 2 score and the gastric residual volume. This shows that the higher the APACHE2 score was the gastric residual volume. And there was a correlation between the APACHE 2 score and the loss of calories. This shows that the higher the APACHE 2 score was the loss of calories. Conclusion: The gastric residual volume of the critically ill patients under enteral nutrition in our hospital was not higher than that presented on the guidelines from the US and Canada. In addition, there was a big difference in the gastric residual volume among the critically ill patients depending on their clinical characteristics. Strict criteria for the gastric residual volume could be a factor for inhibiting proactive enteral nutrition. (KJPEN 2009;2(1):24-29)

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        Vancomycin 안약의 안정성

        윤정원,조은경,김승란,김재연,조영환,노환성 한국병원약사회 2001 병원약사회지 Vol.18 No.2

        Vancomycin eye drop is useful for the ophthalmic infection by methicillin-resistant Staphylococcus aureus(MRSA), methicillin-resistant Staphylococcus epidermidis(MRSE). At neonatal intensive care unit(NICU) in Asan medical center, when we culture the eye discharges of patients and find MRSA, we prepare vancomycin eye drop 30 ㎎/mL and treat the patents with it for two weeks. Until now, we stored vancomycin eye drop under refrigeration and used it within 10 days. But the data for the stability of vancomycin eye drop is not available. So in this study, we intended to evaluate the stability of vancomycin eye drop. We prepared six bottles of vancomycin eye drop with artificial tears to 30 ㎎/mL and evaluated the stability. Three samples were stored under refrigeration and the other three at room temperature. We analysed the contents of vancomycin by HPLC and evaluated osmolarity, pH over 4 weeks. The solutions retained a mean of at least 90% of the initial drug concentration for 21 days under refrigeration and 10 days at room temperature. No substantial change in pH was observed during the study. The osmolarity was maintained similarly. No contamination was detected during the study period. In conclusion, it can be recommended that we use vancomycin eye drop up to 3 weeks from preparation.

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