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Lee, Tae Jin,Kim, Sae Kang,Choi, Byung Sun,Park, Yong Gum,Yoo, Jae Hyung,Park. Eon Sub 중앙대학교 의과대학 의과학연구소 2002 中央醫大誌 Vol.27 No.2
Metallothionein(MT) is a metal binding protein, which plays a major role in metal detoxification and metabolism. In addtion to metal-related physiological roles,many studies have documented expression of MT in various human tumors with correlation to more biologic aggressiveness. However, little is known in gastric carcinomas. In this study, MT expression pattern was examined immunohistochemically using anti-MT monoclonal antibody in 133 cases of gastric carcinomas and compared with macrophage counts, lymphocytic infiltration,P53 protein, PCNA status as well as other clinico-pathological variables. Of the 133 cases examined, over-expression of MT were 42.8%(57/133) and loss of expression were 29.3%(39/133). MT expression pattern was not associated with age, sex, and histologic type of tumors. MT over-exoression tumors showed a tendency to have regional lymph node metastasis. CD68 positive macrophage counts and degree of CD45 positive lymphocytic infiltration was correlated with MT over-expression in gastric carcinomas. In addition, MT over-expression tumors had a significantly higher PCNA positivity compared to the loss of expression tumors. There was no association between MT expression pattern and p53 protein status. These findings suggest that the over-expression of MT protein may play a role in lymph node metastasis and proliferative activities of gastric carcinomas. Therefore, induction of MT could be a predicting marker of tumor progression in gastric cancer.
조준억,신성규,백계진,김세강 해양환경안전학회 2015 해양환경안전학회 학술발표대회 논문집 Vol.2015 No.11
2007년 허베이 스피리트호 해양오염사고 이후 선박의 기름유출 시 응급봉쇄를 위한 마그네틱을 활용한 봉쇄기술이 5년간 개발되었으나 사고현장에서의 실용성이 정체된 원인을 분석하고 현재까지 개발된 봉쇄장치의 활용방안에 관한 제안을 통하여 응급봉쇄장치의 활용도와 실용화율을 높여, 방제기술의 과학화 추진의 필요성을 제안하고자 함. After Hebei Spirit oil spill accident in 2007, Magentic stoper technical system had been developed for 5 years, in order to responds immediately to oil spill from the ship, This study analyze the reason of the impractical oil spill stopper..
임유택,권혁권,정병연,김세강,정용일 대한마취과학회 1996 Korean Journal of Anesthesiology Vol.31 No.6
Local or general anesthesia is essential for safe operation. Patients in good preoperative condition are relatively to tolerable to the operation, but the patients in poor preoperative condition have the high mortality and morbidity during and after the operation. Therefore, we should choose the anesthetic agents and methods, which cause little effect to the patients life. Among the intraventricular blocks, bundle branch is the most common type, and left bundle branch block may progress to a more serious condition of complete heart block. Optimal anesthetic management of patients with cardiovascular disease requires a thorough knowledge of normal cardiac physiology, the circulatory effects of the various anesthetic agents, and the pathophysiology and treatment of these diseases. The authors successfully performed balanced anesthesia in operation of a 63 year old female patient who showed complete left bundle branch block pattern in a preoperative electrocardiographic tracing without any subjective symptoms.