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ICGR15가 10% 이상인 간세포암 환자에서 대량 간절제술에 따른 술후 간부전의 예측인자
이채윤(Chae Yoon Lee),황윤진(Yoon Jin Hwang),천재민(Jae Min Chun),권형준(Hyung Joon Kwon),손준호(Joon Ho Son),김상걸(Sang Gul Kim),윤영국(Yung Kook Yun) 한국간담췌외과학회 2011 한국간담췌외과학회지 Vol.15 No.1
Purpose: Major hepatic resection is sometimes inevitable in patients with impaired liver function. We evaluated risk factors that cause postoperative liver failure after major hepatic resection in patients with over a 10% Indocyanine Green Retention rate at 15 minutes (ICGR15). Methods: From Apr. 2002 to Aug. 2009, 32 patients who had over a 10% rate of ICGR15 underwent major hepatic resection (≥4 Couinaud segments). Among the 32, 9 patients showed postoperative liver failure (less than 50% prothrombine time and/or 5 mg/dl or higher of total bilirubin). This high-risk group was compared to the rest who constituted a low-risk group. Results: Patients with esophageal varix were more common in the high risk group (4 versus 2, p=0.043). Other clinicopathologic features showed no difference between the two groups. We had 2 in-hospital deaths in the high risk group. Conclusion: Great care is needed in patients with esophageal varix and limited liver function during major hepatic resection.