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RISS 인기검색어
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- 저자 : 김범수(Pum Soo Ki m) (검색결과 3 건)
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박효진(Hyo Jin Pack),김범수(Pum Soo Ki m),이정운(Jung Woon Lee),박인서(In Suh Park) 대한소화기학회 1995 대한소화기학회지 Vol.27 No.3
N/A Background/Aims: Esophageal acid clearance is an important mechanism protective against the development of reflux esophagitis. Acid clearance from the esophagus after gastro-esophageal reflux depends on two important mechanisms: esophageal peristalsis to return the displaced gastric content to the stomach and swallowed saliva to neutralize the residual acid that coats the esopha- gea1 mucosa. The present study aims to investigate acid clearance and determine the contributions of esophageal peristalsis, salivation, and gravity. Methods: We performed the acid clearance test, ambulatory 24 hour esophageal pH study, esophageal manometry and saliva study in 16 consecutive patients with reflux esophagitis, and then compared them with normal controls. Results: The clearance of acid instilled into the esophagus was markedly delayed in patients with reflux esophagitis as compared with controls(p0.05). There was a trend towards a lower peristaltic amplitude in patients with reflux esophagitis, but this was statistically not significant. Of the motor events analyzed, there were simultaneous contractions in 4 patients(25.0%), poor wave progression in 4 patients(25.0%), and non-transmitted contraction in 2 patients(12.5%). In patients with reflux esophagitis, the number of reflux episodes, the mean number of reflux episodes greater than 5 minutes, and the percentage of time when the pH was less than 4 were significantly increased compared with controls(p <0.05). The basal and stimulated salivary pH and concentration of bicarbonate in patients with reflux esophagitis did not show a significant difference compared with controls. Conclusions: We found a significant impairment of acid clearance in patients with reflux esophagitis, and some alterations in esophageal peristalsis but no change in salivary functions. (Korean J Gastroenterol 1995;27:275 - 282)
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장관 Behcet 병의 임상적 고찰 및 Sulfasalazine의 치료효과
유효민(Hyo Min Yoo),한광협(Kwang Hyub Han),김범수(Pum Soo Ki m),김원호(Won Ho Kim),강진경(Jin Kyung Kang),박인서(In Suh Park),방동식(Dong Sik Bang) 대한소화기학회 1997 대한소화기학회지 Vol.29 No.4
N/A Background/Aims: Intestinal Behcet disease often has a serious course, and a high frequency of perforation and hemorrhage has been reported. The standard treatment for this disease has not been settled. Methods: For the understanding of the clinical features of intestinal Behcet disease and the therapeutic effects of sulfasalazine, 31 patients with Behcet disease who were admitted to the Yonsei University Medical College Hospital from 1981 to 1993 were reviewed. Results: The mean age wos 35.5 years and the ratio of male to female was 1.8:1. The main clinical symptoms were abdorninal pain, bloody stool, and diarrhea. The intestinal lesions were most comrnonly found in the ileoceca] region(84%) and the most common lesions were discrete ulcers(94%). The localized distribution(81%) of ulcers was rnore prevalent than the diffuse form and the incidence of a single ulcer was similar to that of multiple ulcers. Operation were performed in 13 cases and the indications of operation were peritonitis(3 cases), persisted abdominal pain(2 cases), fistula t'ormation(J case), intestinal obstruction(1 case), massive bleeding(1 case), and obscure diagnosis(S cases). Steroid and colchicine were used in 22 cases and sulfasalazine in 14 cases. Symptomatic or colonoscopic improvernent was more frequent in sulfasalazine(79%) than steroid & colchicine(36%). Conclusions: Intestinal Beh<et diseases should be treated with medical therapy than surgery except the inevitable cases such as bowel perforation or massive lower gastrointestinal hemorrhage. Sulfasalazine is relatively effective and could be used as the primary drug in intestinal Behc,et disease. (Korean J Gastroenterol 1997;29:465-472)
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위암의 심달도 판정에 있어서 내시경 초음파검사의 진단에 영향을 미치는 인자
천상배(Sang Bae Chun),정재복(Jae Bock Chung),송시영(Si Young Song),김범수(Pum Soo Ki m),문영명(Young Myung Moon),강진경(Jin Kyung Kang),박인서(In Suh Park) 대한소화기학회 1994 대한소화기학회지 Vol.26 No.5
N/A Endoscopic ultrasonography(EUS) has been used in assessing the depth of cancer invasion of the stomach. To find out the factors affecting the diagnostic accuracy of EUS in determin- ing the depth of cancer invasion, we analysed 116 cases of gastric cancer performed EUS. One hundred and sixteen cases who were operated for gastric cancer were evaluated by EUS prior to operation. EUS was performed with a 7.5 MHz Olympus EUS. The results were compared with the depth of cancer invasion of the resected specimen and analysed the pathologic findings in mis-staging cases. The degree of vertieal invasion of gastric cancer was classified into 4 stages'. Mucosa, submucosa, muscularis propria, and serosa. Overall accuracy of EUS in determining the depth of cancer invasion was 67.2%(78 of 116 cases). The diagnostic accura- cy in the depth of tumor invasion showed no difference in relation to location of tumor, histo- logic type, and degree of differentiation. In contrast, the diagnostic accuracy was higher in small size(less than 4cm) of tumor than large size(more than 4cm) of tumor, and in non-ul- cerative type than ulcerative type in early gastric cancer. In advanced gastric cancer, the di- agnostic accuracy was higher in large size(more than 6cm) of turnor than small size(less than 2cm) of tumor. The main pathologic findings of overstaging were fibrosis coexisting ulcer and compression of adjacent layer by the tumor, and understaging was microinvasion of cancer. (Korean J Gastroenterol 1994; 26: 806 815)
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