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김도현 ( Do Hyoun Kim ),이성우 ( Sung Woo Lee ),남궁인 ( Gung In Nam ),박종학 ( Jong Hak Park ),김수진 ( Su Jin Kim ),홍윤식 ( Yun Sik Hong ) 대한임상독성학회 2011 대한임상독성학회지 Vol.9 No.1
Vinegar is a very popular ingredient used in many cuisines. It is also known for its beneficial health, beauty and possible weight-loss properties. The authors report on a patient who presented to the emergency department with unstable vital signs complaining of generalized abdominal pain after ingestion of 450 ml of apple cider vinegar. We documented a case of corrosive gastrointestinal injury with persistent metabolic acidosis occurring after ingesting apple cider vinegar with an acetic acid concentration of 12~14%. Toxic damage to the liver and kidney were also observed, peaking on post-ingestion day 3. The patient received supportive care and hemoperfusion for three days without much clinical improvement and died in the seventh day of intensive care due to disseminated intravascular coagulation and multi organ failure. Edible vinegar, when taken in large amounts, is capable of inducing corrosive injuries of the GI tract as well as severe systemic toxicities, such as metabolic acidosis. Safety precautions regarding vinegar deserve more public attention and clinicians also should be astute enough to recognize the potential damage accompanying vinegar ingestion.
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3차원 시간이력해석을 통한 하이브리드 비좌굴가새의 풍진동제어능력 평가
김상대(Kim Sang-Dae),강경환(Kang Kyoung-Hwan),고창균(Ko Chang-Kyun),김도현(Kim Do-Hyoun),주영규(Ju Young-Kyu) 대한건축학회 2010 大韓建築學會論文集 : 構造系 Vol.26 No.10
Buckling Restrained Braces(BRBs) show good seismic behavior. They do not dissipate energy, however, when they are subjected to wind. Hybrid Buckling Restrained Braces(H-BRBs), which can improve the wind performance of the BRB system, are a kind of hybrid damper system composed of a viscoelastic damper and BRBs. In this paper, the H-BRBs subjected to wind load was explored in the method of time history analysis for 3-dimensional model. The wind load for serviceability design was obtained from the wind tunnel test. Along wind and across wind load datas were used. Steel brace, buckling restrained brace, and H-BRB were compared in terms of the roof displacement, the roof acceleration, hysteresis loops. It was concluded that H-BRBs show good performance for the wind load and have improved the high-rise building performance at a serviceability level.
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박성준 ( Sung Jun Park ),박종학 ( Jong Hak Park ),엄인경 ( In Kyung Um ),박경애 ( Kyung Ae Park ),김도현 ( Do Hyoun Kim ),김수진 ( Su Jin Kim ),이성우 ( Sung Woo Lee ),홍윤식 ( Yun Sik Hong ) 대한임상독성학회 2011 대한임상독성학회지 Vol.9 No.1
Purpose: This study was designed to analyze the contributing factors, as well as the incidence and nature of the cardiac toxicity, in patients presenting with diphenhydramine overdose. Methods: We retrospectively reviewed the medical records of the intoxicated patients who presented to the ED of Korea University Anam Hospital from January 2008 to December 2010. Those patients who visited due to a diphenhydramine overdose were selected and the following features were recorded for analysis: the general characteristics, vital signs, the amount of ingested diphenhydramine, the time interval from ingestion to presentation, the coingested drugs (if any), the toxicities and the ECG findings. Cardiac toxicity, while defined mainly in terms of the temporary ECG changes such as QTc prolongation, right axis deviation, QRS widening, high degree AV block and ischemic changes, also encompassed cardiogenic shock, which is a clinical finding. Results: A total of eighteen patients were enrolled. Of the eighteen patients, eight had ingested diphenhydramine only, while ten had ingested other drugs in addition to diphenhydramine. The most commonly observed toxicity following diphenhydramine overdose included cardiac toxicity (78%). Cardiac toxicity was observed in all the patients who presented to the emergency department 2 hours after ingestion. The patients with QTc prolongation turned out to have ingested significantly larger amounts of diphenhydramine. Conclusion: QTc prolongation and right axis deviation were common findings for the patients with a diphenhydramine overdose. QTc prolongation was more likely to occur with ingesting larger amounts of diphenhydramine. Close monitoring is mandatory for patients who have ingested large amounts of diphenhydramine to prevent such potentially lethal cardiac toxicity.
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