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삼백초 추출물의 3T3-L1 세포에 대한 지방축적 억제효과
신옥수(Ok-Su Shin),신연호(Youn-Ho Shin),이강혁(Kang-Hyun Lee),김건용(Gun-Yong Kim),김기호(Ki-Ho Kim),박정극(Jung-Keug Park),안재일(Jae-Il Ahn),송계용(Kye-Yong Song) 한국생물공학회 2012 KSBB Journal Vol.27 No.6
Obesity increases the risk of many adult diseases, such as atherosclerosis, diabetes, hypertension, ischemic heart disease and breast cancer. Inhibition of adipogenesis is an effective way in the anti-obesity management. Because of main components of Saururus chinensis is flavonoid, it has been showed some improvement by its antioxidant effects on the atherosclerosis, heart disease and diabetic hyperlipidemia. But mechanism of anti-obesity effect of S. chinensis is not clear. We investigated the effects of ethanol extracts of S. chinensis on adipogenesis in the 3T3-L1 pre-adipocyte. The 3T3-L1 cell line is commonly used to study adipogenesis in vitro. In this study, ethanol extracts of S. chinensis significantly decrease the lipid accumulation in the 3T3-L1 cells proved by measuring triglyceride contents and Oil red O staining. The proposed mechanism of inhibition of adipogenesis in the 3T3-L1 cells with ethanol extracts of S. chinensis is down-regulation of transcriptional factors and adipocytespecific genes such CCAAT/enhancer binding protein α (C/EBPα) and Peroxisome proliferator activated receptor γ (PPARγ) in concentration dependent pattern. These results suggest that ethanol extracts of S. chinensis inhibits adipognesis in the 3T3-L1 cells and can be used as a safe and efficient natural substance to manage anti-obesity.
태양광자동차의 발전모듈 온도 특성에 따른 최적 설계 기술
조민희 ( Min Hee Cho ),윤진원 ( Jin Won Yoon ),김건용 ( Gun Yong Kim ),허재원 ( Jae Won Huh ),이지수 ( Ji Soo Lee ),황현창 ( Hyun Chang Hwang ),이계복 ( Kye Bock Lee ),이석호 ( Soek Ho Rhi ) 충북대학교 산업과학기술연구소 2014 산업과학기술연구 논문집 Vol.28 No.2
Solar cars combine technologies typically used in the alternative energy and automotive industries. The design of a solar vehicle is severely limited by the amount of supplied solar energy input into the car. Currently, most solar cars have been built for the purpose of solar car racing or prototyping of solar energy usage. But in the present study, solar car designed with given solar cells was investigated in terms of daily irradiation, cell temperature and geometrical characteristics to improve the solar power generation and the driving efficiency. Mainly driving power of solar car depends on the performance of photovoltaic cells to convert sunlight into electricity. Unlike solar thermal energy which converts solar energy to heat for either household purposes, industrial purposes or to be converted to electricity, PV cells directly convert sunlight into electricity. Present solar car system``s power output was affected by module inclination and module temperature. Intensity of solar irradiation depending on time was also severely depending on the position of sun. Decreasing cell temperature leads to increase power generation.