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국진이 ( Jin Yi Kuk ),윤소연 ( So Yean Yoon ),김민지 ( Min Ji Kim ),이정원 ( Jeong Won Lee ),김병기 ( Byoung Gie Kim ),배덕수 ( Duk Soo Bae ) 대한산부인과학회 2012 Obstetrics & Gynecology Science Vol.55 No.10
Peripheral primitive neuroectodermal tumor (PNET) is a small round tumor belonging to the PNET/Ewing`s sarcoma family classified based on location in the body. There have been a small number of case reports of PNET arising in the ovary. We present extremely rare case of PNET of the ovary occurring in a 32-year-old pregnant woman, which was detected during her second Cesarean section. She had a past history of oophorectomy due to a huge mature solid teratoma in left ovary during her first Cesarean section. She got the operation of right salpingoophorectomy during the second Cesarean section at local gynecologic clinic and referred to our institute. Magnetic resonance imaging and positron emission tomography revealed the PNET was metastased to the peritoneum and the lymph nodes. We had persecuted vincristine, doxorubicin, cyclophosphamide, and etoposide/ifosfamide 8 cycles. There has been no evidence of local tumor recurrence and metastasis after the chemotherapy until now.
정상 염색체 여성에서의 성선 이형성과 난소 미분화세포종이 동반된
윤소연 ( So Yeon Yoon ),박향기 ( Hyang Gi Park ),국진이 ( Jin Yi Kuk ),옥순애 ( Soon Ae Oak ),박종훈 ( Jong Hoon Park ) 대한산부인과학회 2012 Obstetrics & Gynecology Science Vol.55 No.10
Gonadal dysgenesis occurs in rare case of ovarian tumor. Most tumors associated with gonadal dysgenesis were gonadoblastomas and dysgerminomas. In addition, premature ovarian insufficiency associated with these ovarian tumors in normal chromosomal type had not reported in many cases. A 29-year-old nulligravida woman who was concurrented with ovarian dysgerminoma and fibroma is presented. Measurements were made on serum lactate dehydrogenase, CA-125, CA 19-9 and pelvis ultrasonography and computed tomography. The clinical stage was IA and right salpingo-oophorectomy and wedge resection of the left ovary were done. On laboratory finding after operation on her serum follicular stimulating hormone was increased and E2 was decreased. The result of chromosomal analysis was 46,XX, normal. We represent here with brief review of literature one case of gonadal dysgenesis in nulligravida woman, associated with dysgerminoma, with normal karyotype.