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카바프로스타싸이클린의 중간체로 이용가능한 히드록시싸이클로펜탄의 합성
서영거(Young Ger Suh),구본암(Bon Am Koo),정재경(Jae Kyung Jung),조윤상(Young Sang Cho),나운용(Woon Lyong Lah) 대한약학회 1993 약학회지 Vol.37 No.3
An efficient synthetic route to the trisubstituted cyclopentane as an useful synthetic intrermediate for carbaprostacyclin is described. Ireland Claisen rearrangement of a hydroxylactone has been employed as a key reaction.
Macrolide의 새로운 합성 -8-Membered Lactone의 합성-
서영거(Young Ger Suh),구본암(Bon Am Koo),조윤상(Youn Sang Cho) 대한약학회 1990 약학회지 Vol.34 No.3
An efficient synthetic route to macrolide is described. Eight-membered lactone was synthesized via palladium catalyzed intramolecular alkylation of allylic carbonate in high yield.
카바프로스타싸이클린 중간체의 합성: 1-Alkoxy-benzenesulfonyl-cyano-4-ethenyl cyclopeptane의 입체선택적 합성
서영거(Young Ger Suh),정재경(Jae Kyoung Jung),구본암(Bon Am Koo),최영기(Young Gi Choi),조윤상(Youn Sang Cho) 대한약학회 1995 약학회지 Vol.39 No.1
An efficient and stereoselective synthetic route to the trisubstituted hydroxy cyclopentane as an useful synthetic intermediate for carbaprostacyclin is described. Pd(O)-mediated intramolecular alkylation of allylic carbonate has been employed as a key reaction.